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PSORIASIS 2016

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2 papers 0 to 25 followers
By EFRAIN PAEZ Internal Medicine since 1988. Interested in all aspects of Medicine.
https://www.readbyqxmd.com/read/27461230/from-the-medical-board-of-the-national-psoriasis-foundation-perioperative-management-of-systemic-immunomodulatory-agents-in-patients-with-psoriasis-and-psoriatic-arthritis
#1
REVIEW
Young M Choi, Maya Debbaneh, Jeffrey M Weinberg, Paul S Yamauchi, Abby S Van Voorhees, April W Armstrong, Michael Siegel, Jashin J Wu
Treatment with systemic immunomodulatory agents is indicated for patients with moderate to severe plaque psoriasis and psoriatic arthritis. In these patients, surgery may confer an increased risk of infectious or surgical complications. We conducted a literature review to examine studies addressing the use of methotrexate, cyclosporine, and targeted immunomodulatory agents (tumor necrosis factor-alfa inhibitors, interleukin [IL]-12/23 inhibitors, IL-17 inhibitors) in patients undergoing surgery. We examined 46 total studies; the majority were retrospective studies in patients with rheumatoid arthritis and inflammatory bowel disease...
October 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27324314/serious-infections-in-hospitalized-patients-with-psoriasis-in-the-united-states
#2
Derek Y Hsu, Kenneth Gordon, Jonathan I Silverberg
BACKGROUND: Patients with psoriasis have multiple risk factors for serious infections, including immune dysregulation, systemic immunosuppressive medications, and comorbid health conditions. OBJECTIVE: We sought to determine rates and predictors of serious infections in hospitalized psoriasis patients and quantify costs of care, length of stay, and mortality. METHODS: We conducted a cross-sectional study of the Nationwide Inpatient Sample from 2002 to 2012, containing a representative 20% sample of all hospitalizations in the United States...
August 2016: Journal of the American Academy of Dermatology
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