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Ciorsti MacIntyre, Neal K Lakdawala
No abstract text is available yet for this article.
May 10, 2016: Circulation
Maarten van den Berge, René Aalbers
It is increasingly recognized that both asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous diseases with a large inter-individual variability with respect to their clinical expression, disease progression, and responsiveness to the available treatments. The introduction of asthma-COPD overlap syndrome (ACOS) may lead to a better clinical characterization and improved treatment of patients with obstructive airways disease. However, it is still in its early phase and several improvements will have to be made...
2016: Journal of Asthma and Allergy
James J Chamberlain, Andrew S Rhinehart, Charles F Shaefer, Annie Neuman
DESCRIPTION: The American Diabetes Association (ADA) published the 2016 Standards of Medical Care in Diabetes (Standards) to provide clinicians, patients, researchers, payers, and other interested parties with the components of diabetes care, general treatment goals, and tools to evaluate the quality of care. METHODS: The ADA Professional Practice Committee performed a systematic search on MEDLINE to revise or clarify recommendations based on new evidence. The committee assigns the recommendations a rating of A, B, or C, depending on the quality of evidence...
April 19, 2016: Annals of Internal Medicine
M Ruparel, S L Quaife, N Navani, J Wardle, S M Janes, D R Baldwin
Lung cancer screening has come a long way since the early studies with chest X-ray. Advancing technology and progress in the processing of images have enabled low dose CT to be tried and tested, and evidence suggests its use can result in a significant mortality benefit. There are several issues that need refining in order to successfully implement screening in the UK and elsewhere. Some countries have started patchy implementation of screening and there is increased recognition that the appropriate management of pulmonary nodules is crucial to optimise benefits of early detection, while reducing harm caused by inappropriate medical intervention...
April 2016: Thorax
Marina Basarab, Conor Bowman, Emma J Aarons, Ian Cropley
No abstract text is available yet for this article.
February 26, 2016: BMJ: British Medical Journal
S Quirce, O Vandenplas, P Campo, M J Cruz, F de Blay, D Koschel, G Moscato, G Pala, M Raulf, J Sastre, A Siracusa, S M Tarlo, J Walusiak-Skorupa, Y Cormier
The aim of this document was to provide a critical review of the current knowledge on hypersensitivity pneumonitis caused by the occupational environment and to propose practical guidance for the diagnosis and management of this condition. Occupational hypersensitivity pneumonitis (OHP) is an immunologic lung disease resulting from lymphocytic and frequently granulomatous inflammation of the peripheral airways, alveoli, and surrounding interstitial tissue which develops as the result of a non-IgE-mediated allergic reaction to a variety of organic materials or low molecular weight agents that are present in the workplace...
June 2016: Allergy
Brandon Galm, Sean M Bagshaw
No abstract text is available yet for this article.
July 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Judy Ozkan
No abstract text is available yet for this article.
February 14, 2016: European Heart Journal
Septimiu Dan Murgu, Katarine Egressy, Balaji Laxmanan, Guillermo Doblare, Rosamaria Ortiz-Comino, D Kyle Hogarth
The purpose of this article is to provide an update on methods for palliating symptoms in patients with histologically benign and malignant central airway obstruction. We review the published literature within the past decade on postintubation, posttracheostomy, and TB- and transplant-related airway strictures; tracheobronchomalacia; and malignant airway obstruction. We review terminology, classification systems, and parameters that impact treatment decisions. The focus is on how airway stent insertion fits into the best algorithm of care...
August 2016: Chest
Andrew W Hitchings, Emma H Baker
No abstract text is available yet for this article.
March 2016: Thorax
Roger Collier
No abstract text is available yet for this article.
March 1, 2016: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
Mona Bafadhel, Neil J Greening, Theresa C Harvey-Dunstan, Johanna E A Williams, Michael D Morgan, Christopher E Brightling, Syed F Hussain, Ian D Pavord, Sally J Singh, Michael C Steiner
BACKGROUND: Patients with moderate exacerbations of COPD and the eosinophilic phenotype have better outcomes with prednisolone. Whether this outcome is similar in patients hospitalized with a severe exacerbation of COPD is unclear. We investigated the rate of recovery of eosinophilic and noneosinophilic exacerbations in patients participating in a multicenter randomized controlled trial assessing health outcomes in hospitalized exacerbations. METHODS: Patients were recruited at presentation to the hospital with an exacerbation of COPD...
August 2016: Chest
Philippe Bordier, Aurelia Lataste, Pauline Hofmann, Frederic Robert, Ghalia Bourenane
Chronic heart failure (CHF) is a public health problem which affects >2% of the adult population, with high morbidity, mortality, and financial cost. Sleep apnea, prevalent in >50% of patients with CHF, can aggravate vital prognosis due to worsening of heart failure. It is considered that a decrease in the apnea-hypopnea load may improve outcomes for those patients. Nocturnal non invasive ventilation can be proposed to treat sleep apnea in this situation, there being few alternatives. The present review concerns the use of nocturnal oxygen therapy (NOT) in patients suffering from both CHF and sleep apnea...
January 2016: Sleep Medicine
Pauline Pradere, Clément Gauvain, Claire Danel, Marie Pierre Debray, Raphael Borie, Laurent Plantier, Hervé Mal, Michel Aubier, Bruno Crestani, Camille Taillé
OBJECTIVE: To describe a new entity characterized by airway-centered fibroelastosis. METHODS: We identified cases with prominent airway-centered elastosis in lung samples, and little or no pleural involvement identified through a pathologic database at a single institution over an 8-year period. RESULTS: Airway-centered fibroelastosis was characterized by (1) extensive airway-centered fibroelastosis of the upper lobes on histopathology and (2) marked bronchial abnormalities with bronchial wall thickening, bronchial wall deformation, and bronchiectasis, along with progressive parenchymal retraction and predominantly subpleural upper-lobe consolidations on high-resolution CT...
March 2016: Chest
J Wernerman, G H Sigurdsson
No abstract text is available yet for this article.
February 2016: Acta Anaesthesiologica Scandinavica
Marc Miravitlles, Claus Vogelmeier, Nicolas Roche, David Halpin, João Cardoso, Alexander G Chuchalin, Hannu Kankaanranta, Thomas Sandström, Paweł Śliwiński, Jaromir Zatloukal, Francesco Blasi
The quality of care can be improved by the development and implementation of evidence-based treatment guidelines. Different national guidelines for chronic obstructive pulmonary disease (COPD) exist in Europe and relevant differences may exist among them.This was an evaluation of COPD treatment guidelines published in Europe and Russia in the past 7 years. Each guideline was reviewed in detail and information about the most important aspects of patient diagnosis, risk stratification and pharmacotherapy was extracted following a standardised process...
February 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Thomas F Lüscher
No abstract text is available yet for this article.
January 14, 2016: European Heart Journal
S Vincent Rajkumar, Shaji Kumar
The diagnosis and treatment of multiple myeloma has changed dramatically in the past decade. The disease definition has been updated to include highly specific biomarkers in addition to established markers of end-organ damage. The staging system has been revised to combine both measures of tumor burden and disease biology. Advances in therapy have resulted in a marked improvement in overall survival. New drugs introduced in the past few years include carfilzomib, pomalidomide, panobinostat, ixazomib, elotuzumab, and daratumumab...
January 2016: Mayo Clinic Proceedings
Anthony S Fauci, David M Morens
The explosive pandemic of Zika virus infection occurring throughout South America, Central America, and the Caribbean (see map) and potentially threatening the United States is the most recent of four unexpected arrivals of important arthropod-borne viral diseases in the Western Hemisphere over the..
February 18, 2016: New England Journal of Medicine
Barbara Jones, Nathan Dean, Richard Wunderink, Marianna Sockrider
No abstract text is available yet for this article.
January 1, 2016: American Journal of Respiratory and Critical Care Medicine
2016-06-21 02:55:11
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