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Outstanding Clinical Review

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2 papers 0 to 25 followers
https://www.readbyqxmd.com/read/27107491/procalcitonin-as-an-early-marker-of-the-need-for-invasive-respiratory-or-vasopressor-support-in-adults-with-community-acquired-pneumonia
#1
Wesley H Self, Carlos G Grijalva, Derek J Williams, Alison Woodworth, Robert A Balk, Sherene Fakhran, Yuwei Zhu, D Mark Courtney, James Chappell, Evan J Anderson, Chao Qi, Grant W Waterer, Christopher Trabue, Anna M Bramley, Seema Jain, Kathryn M Edwards, Richard G Wunderink
BACKGROUND: Predicting the need for intensive care among adults with community-acquired pneumonia (CAP) remains challenging. METHODS: Using a multicenter prospective cohort study of adults hospitalized with CAP, we evaluated the association of serum procalcitonin (PCT) concentration at hospital presentation with the need for invasive respiratory or vasopressor support (IRVS), or both, within 72 h. Logistic regression was used to model this association, with results reported as the estimated risk of IRVS for a given PCT concentration...
October 2016: Chest
https://www.readbyqxmd.com/read/15156485/anemia-in-hiv-infection-clinical-impact-and-evidence-based-management-strategies
#2
Paul A Volberding, Alexandra M Levine, Douglas Dieterich, Donna Mildvan, Ronald Mitsuyasu, Michael Saag
Anemia in human immunodeficiency virus (HIV)-infected patients can have serious implications, which vary from functional and quality-of-life decrements to an association with disease progression and decreased survival. In 2002, 16 members of the Anemia in HIV Working Group, an expert panel of physicians involved in the care of HIV-infected patients that met first in 1998, reconvened to assess new data and to translate these data into evidence-based treatment guidelines. The group reached consensus on the prevalence of anemia in the highly active antiretroviral therapy era; the risk factors that are independently associated with the development of anemia; the impact of anemia on quality of life, physical functioning, and survival; the impact of the treatment of hepatitis C virus coinfection on anemia in HIV-infected patients; evidence-based guidelines for treatment of anemia in HIV-infected patients, including the therapeutic role of epoetin alfa; and directions for future research...
May 15, 2004: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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