collection
https://read.qxmd.com/read/28151434/detection-of-atrial-fibrillation-episodes-using-a-wristband-device
#21
JOURNAL ARTICLE
Valentina D A Corino, Rita Laureanti, Lorenzo Ferranti, Giorgio Scarpini, Federico Lombardi, Luca T Mainardi
OBJECTIVE: Undiagnosed atrial fibrillation (AF) patients are at high risk of cardioembolic stroke or other complications. The aim of this study was to analyze the blood volume pulse (BVP) signals obtained from a wristband device and develop an algorithm for discriminating AF from normal sinus rhythm (NSR) or from other arrhythmias (ARR). APPROACH: Thirty patients with AF, 9 with ARR and 31 in NSR were included in the study. The recordings were obtained at rest from Empatica E4 wristband device and lasted 10 min...
May 2017: Physiological Measurement
https://read.qxmd.com/read/28110303/stroke-prevention-in-atrial-fibrillation
#22
JOURNAL ARTICLE
Gregory Y H Lip
No abstract text is available yet for this article.
January 1, 2017: European Heart Journal
https://read.qxmd.com/read/28110309/close-connections-between-contraction-and-rhythm-a-new-genetic-cause-of-atrial-fibrillation-cardiomyopathy-and-what-it-can-teach-us
#23
EDITORIAL
Stanley Nattel
No abstract text is available yet for this article.
January 1, 2017: European Heart Journal
https://read.qxmd.com/read/28129965/genetic-risk-scores-for-atrial-fibrillation-do-they-improve-risk-estimation
#24
EDITORIAL
Henry D Huang, Dawood Darbar
No abstract text is available yet for this article.
April 2017: Canadian Journal of Cardiology
https://read.qxmd.com/read/28104790/contemporary-management-of-patients-undergoing-atrial-fibrillation-ablation-in-hospital-and-1-year-follow-up-findings-from-the-esc-ehra-atrial-fibrillation-ablation-long-term-registry
#25
MULTICENTER STUDY
Elena Arbelo, Josep Brugada, Carina Blomström-Lundqvist, Cécile Laroche, Josef Kautzner, Evgeny Pokushalov, Pekka Raatikainen, Michael Efremidis, Gerhard Hindricks, Alberto Barrera, Aldo Maggioni, Luigi Tavazzi, Nikolaos Dagres
AIMS: The ESC-EHRA Atrial Fibrillation Ablation Long-Term registry is a prospective, multinational study that aims at providing an accurate picture of contemporary real-world ablation for atrial fibrillation (AFib) and its outcome. METHODS AND RESULTS: A total of 104 centres in 27 European countries participated and were asked to enrol 20-50 consecutive patients scheduled for first and re-do AFib ablation. Pre-procedural, procedural and 1-year follow-up data were captured on a web-based electronic case record form...
May 1, 2017: European Heart Journal
https://read.qxmd.com/read/28028066/head-to-head-comparison-of-the-alivecor-heart-monitor-and-microlife-watchbp-office-afib-for-atrial-fibrillation-screening-in-a-primary-care-setting
#26
COMPARATIVE STUDY
Pak-Hei Chan, Chun-Ka Wong, Louise Pun, Yu-Fai Wong, Michelle Man-Ying Wong, Daniel Wai-Sing Chu, Chung-Wah Siu
No abstract text is available yet for this article.
January 3, 2017: Circulation
https://read.qxmd.com/read/27933666/risk-of-stroke-and-recurrence-after-af-ablation-in-patients-with-an-initial-event-free-period-of-12-months
#27
JOURNAL ARTICLE
Simon Kochhäuser, Pouria Alipour, Tanjah Haig-Carter, Kathleen Trought, Philip Hache, Yaariv Khaykin, Zaev Wulffhart, Alfredo Pantano, Bernice Tsang, David Birnie, Atul Verma
INTRODUCTION: Because of the unclear prognostic effects of ablation of atrial fibrillation (AF), oral anticoagulation (OAC) is often continued after ablation even in asymptomatic patients. We sought to determine the frequency of stroke and AF recurrence in patients on and off therapeutic OAC 1 year after a successful AF ablation. METHODS AND RESULTS: Patients that underwent AF ablation and were free of AF 12 months after ablation were selected from our AF database...
March 2017: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/27705839/30-year-nationwide-trends-in-incidence-of-atrial-fibrillation-in-denmark-and-associated-5-year-risk-of-heart-failure-stroke-and-death
#28
JOURNAL ARTICLE
Morten Schmidt, Sinna Pilgaard Ulrichsen, Lars Pedersen, Hans Erik Bøtker, Jens Cosedis Nielsen, Henrik Toft Sørensen
BACKGROUND: Long-term nationwide trends in atrial fibrillation (AF) incidence and 5-year outcomes are rare. METHODS: We conducted a population-based cohort study using the Danish National Patient Registry covering all Danish hospitals. We computed standardized incidence rates during 1983-2012. We used Cox regression to estimate hazard ratios (HRs) of heart failure, stroke, and death within 5years, comparing 5-year calendar periods with the earliest period (1983-1987) as reference...
December 15, 2016: International Journal of Cardiology
https://read.qxmd.com/read/27825974/complexity-of-af-genetic-susceptibility-begets-complexity-of-interpretation
#29
EDITORIAL
Lee L Eckhardt, Jonathan C Makielski
No abstract text is available yet for this article.
February 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/27725286/stabilizing-ryanodine-receptor-gating-quiets-arrhythmogenic-events-in-human-heart-failure-and-atrial-fibrillation
#30
EDITORIAL
Donald M Bers
No abstract text is available yet for this article.
March 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/27746384/role-of-ranolazine-in-the-prevention-and-treatment-of-atrial-fibrillation-a-meta-analysis-of-randomized-clinical-trials
#31
REVIEW
Mengqi Gong, Zhiwei Zhang, Nikolaos Fragakis, Panagiotis Korantzopoulos, Konstantinos P Letsas, Guangping Li, Gan-Xin Yan, Tong Liu
BACKGROUND: Randomized controlled trials (RCTs) on the use of ranolazine (RN) for prevention and cardioversion of atrial fibrillation (AF) have yielded conflicting results. OBJECTIVE: The purpose of this study was to conduct a meta-analysis of RCTs to examine the potential role of RN in the prevention and cardioversion of AF. METHODS: PubMed and EMBASE were searched until June 2016. Of 484 initially identified studies, 8 RCTs were finally analyzed...
January 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/27756707/unique-cardiomyocyte-ultrastructure-in-atria-role-of-t-tubules-in-subcellular-ca-2-signaling-and-atrial-arrhythmogenesis
#32
EDITORIAL
Dobromir Dobrev
No abstract text is available yet for this article.
February 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/27756709/gain-of-function-mutations-in-gata6-lead-to-atrial-fibrillation
#33
JOURNAL ARTICLE
Nathan R Tucker, Saagar Mahida, Jiangchuan Ye, Elizabeth J Abraham, Julie A Mina, Victoria A Parsons, Michael A McLellan, Marisa A Shea, Alan Hanley, Emelia J Benjamin, David J Milan, Honghuang Lin, Patrick T Ellinor
BACKGROUND: The genetic basis of atrial fibrillation (AF) and congenital heart disease remains incompletely understood. OBJECTIVE: We sought to determine the causative mutation in a family with AF, atrial septal defects, and ventricular septal defects. METHODS: We evaluated a pedigree with 16 family members, 1 with an atrial septal defect, 1 with a ventricular septal defect, and 3 with AF; we performed whole exome sequencing in 3 affected family members...
February 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/27742809/a-frameshift-deletion-in-the-sarcomere-gene-myl4-causes-early-onset-familial-atrial-fibrillation
#34
MULTICENTER STUDY
Daniel F Gudbjartsson, Hilma Holm, Patrick Sulem, Gisli Masson, Asmundur Oddsson, Olafur Th Magnusson, Jona Saemundsdottir, Hafdis Th Helgadottir, Hannes Helgason, Hrefna Johannsdottir, Solveig Gretarsdottir, Sigurjon A Gudjonsson, Inger Njølstad, Maja-Lisa Løchen, Larry Baum, Ronald C W Ma, Gunnlaugur Sigfusson, Augustine Kong, Guðmundur Thorgeirsson, Jon Th Sverrisson, Unnur Thorsteinsdottir, Kari Stefansson, David O Arnar
AIMS: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in man, causing substantial morbidity and mortality with a major worldwide public health impact. It is increasingly recognized as a highly heritable condition. This study aimed to determine genetic risk factors for early-onset AF. METHODS AND RESULTS: We sequenced the whole genomes of 8453 Icelanders and imputed genotypes of the 25.5 million sequence variants we discovered into 1799 Icelanders with early-onset AF (diagnosed before 60 years of age) and 337 453 controls...
January 1, 2017: European Heart Journal
https://read.qxmd.com/read/27650424/antiarrhythmic-effects-of-dantrolene-in-human-diseased-cardiomyocytes
#35
JOURNAL ARTICLE
Nico Hartmann, Steffen Pabel, Jonas Herting, Felix Schatter, André Renner, Jan Gummert, Hanna Schotola, Bernhard C Danner, Lars S Maier, Norbert Frey, Gerd Hasenfuss, Thomas H Fischer, Samuel Sossalla
BACKGROUND: Cardiac type 2 ryanodine receptors (RyR2 s) play a pivotal role in cellular electrophysiology and contractility. Increased RyR2 -mediated diastolic sarcoplasmic reticulum (SR) Ca2+ release is linked to heart failure (HF) and arrhythmias. Dantrolene, a drug used for the treatment of malignant hyperthermia, is known to stabilize RyRs in skeletal muscle. OBJECTIVE: The purpose of this study was to investigate the effects of dantrolene on arrhythmogenic triggers and contractile function in human atrial fibrillation (AF) and HF cardiomyocytes (CM)...
March 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/27651389/the-search-for-the-tipping-point-on-when-to-anticoagulate-patients-with-atrial-fibrillation
#36
EDITORIAL
Hein Heidbuchel
No abstract text is available yet for this article.
February 2017: Heart
https://read.qxmd.com/read/27609430/2016-focused-update-of-the-canadian-cardiovascular-society-guidelines-for-the-management-of-atrial-fibrillation
#37
REVIEW
Laurent Macle, John Cairns, Kori Leblanc, Teresa Tsang, Allan Skanes, Jafna L Cox, Jeff S Healey, Alan Bell, Louise Pilote, Jason G Andrade, L Brent Mitchell, Clare Atzema, David Gladstone, Mike Sharma, Subodh Verma, Stuart Connolly, Paul Dorian, Ratika Parkash, Mario Talajic, Stanley Nattel, Atul Verma
The Canadian Cardiovascular Society (CCS) Atrial Fibrillation (AF) Guidelines Committee provides periodic reviews of new data to produce focused updates that address clinically important advances in AF management. This 2016 Focused Update deals with: (1) the management of antithrombotic therapy for AF patients in the context of the various clinical presentations of coronary artery disease; (2) real-life data with non-vitamin K antagonist oral anticoagulants; (3) the use of antidotes for the reversal of non-vitamin K antagonist oral anticoagulants; (4) digoxin as a rate control agent; (5) perioperative anticoagulation management; and (6) AF surgical therapy including the prevention and treatment of AF after cardiac surgery...
October 2016: Canadian Journal of Cardiology
https://read.qxmd.com/read/27601603/pathophysiology-of-atrial-fibrillation-in-endurance-athletes-an-overview-of-recent-findings
#38
REVIEW
Fabian Sanchis-Gomar, Alejandro Lucia
No abstract text is available yet for this article.
December 6, 2016: Canadian Medical Association Journal: CMAJ
https://read.qxmd.com/read/27567408/2016-esc-guidelines-for-the-management-of-atrial-fibrillation-developed-in-collaboration-with-eacts
#39
JOURNAL ARTICLE
Paulus Kirchhof, Stefano Benussi, Dipak Kotecha, Anders Ahlsson, Dan Atar, Barbara Casadei, Manuel Castella, Hans-Christoph Diener, Hein Heidbuchel, Jeroen Hendriks, Gerhard Hindricks, Antonis S Manolis, Jonas Oldgren, Bogdan Alexandru Popescu, Ulrich Schotten, Bart Van Putte, Panagiotis Vardas
No abstract text is available yet for this article.
October 7, 2016: European Heart Journal
https://read.qxmd.com/read/27569443/balance-between-sodium-and-calcium-currents-underlying-chronic-atrial-fibrillation-termination-an-in-silico-intersubject-variability-study
#40
JOURNAL ARTICLE
Alejandro Liberos, Alfonso Bueno-Orovio, Miguel Rodrigo, Ursula Ravens, Ismael Hernandez-Romero, Francisco Fernandez-Aviles, Maria S Guillem, Blanca Rodriguez, Andreu M Climent
BACKGROUND: Atrial remodeling as a result of long-standing persistent atrial fibrillation (AF) induces substrate modifications that lead to different perpetuation mechanisms than in paroxysmal AF and a reduction in the efficacy of antiarrhythmic treatments. OBJECTIVE: The purpose of this study was to identify the ionic current modifications that could destabilize reentries during chronic AF and serve to personalize antiarrhythmic strategies. METHODS: A population of 173 mathematical models of remodeled human atrial tissue with realistic intersubject variability was developed based on action potential recordings of 149 patients diagnosed with AF...
December 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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