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aki advancement

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Mohammad Alsady, Ruben Baumgarten, Peter M T Deen, Theun de Groot
Trace amounts of lithium are essential for our physical and mental health, and administration of lithium has improved the quality of life of millions of patients with bipolar disorder for >60 years. However, in a substantial number of patients with bipolar disorder, long-term lithium therapy comes at the cost of severe renal side effects, including nephrogenic diabetes insipidus and rarely, ESRD. Although the mechanisms underlying the lithium-induced renal pathologies are becoming clearer, several recent animal studies revealed that short-term administration of lower amounts of lithium prevents different forms of experimental AKI...
June 2016: Journal of the American Society of Nephrology: JASN
Claudio Ronco
No abstract text is available yet for this article.
January 2016: Nephrology, Dialysis, Transplantation
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