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RPHICUTeaching2016.1-Neurology

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6 papers 0 to 25 followers Research Papers used in aid of the in-house ICU registrar teaching programme at Royal Perth Hospital in the first half of 2016.
https://www.readbyqxmd.com/read/23713578/rapid-blood-pressure-lowering-in-patients-with-acute-intracerebral-hemorrhage
#1
RANDOMIZED CONTROLLED TRIAL
Craig S Anderson, Emma Heeley, Yining Huang, Jiguang Wang, Christian Stapf, Candice Delcourt, Richard Lindley, Thompson Robinson, Pablo Lavados, Bruce Neal, Jun Hata, Hisatomi Arima, Mark Parsons, Yuechun Li, Jinchao Wang, Stephane Heritier, Qiang Li, Mark Woodward, R John Simes, Stephen M Davis, John Chalmers
BACKGROUND: Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known. METHODS: We randomly assigned 2839 patients who had had a spontaneous intracerebral hemorrhage within the previous 6 hours and who had elevated systolic blood pressure to receive intensive treatment to lower their blood pressure (with a target systolic level of <140 mm Hg within 1 hour) or guideline-recommended treatment (with a target systolic level of <180 mm Hg) with the use of agents of the physician's choosing...
June 20, 2013: New England Journal of Medicine
https://www.readbyqxmd.com/read/22694000/guillain-barr%C3%A3-syndrome
#2
REVIEW
Nobuhiro Yuki, Hans-Peter Hartung
No abstract text is available yet for this article.
June 14, 2012: New England Journal of Medicine
https://www.readbyqxmd.com/read/21169826/the-acute-management-of-intracerebral-hemorrhage
#3
REVIEW
Oliver Flower, Martin Smith
PURPOSE OF REVIEW: Spontaneous intracerebral hemorrhage (ICH) is associated with high morbidity and mortality, providing substantial scope for improvements in outcome. This review will discuss recent developments and present consensus evidence for the management of ICH. RECENT FINDINGS: Intracranial management strategies focus on preventing further bleeding and minimizing the risk of hematoma expansion and cerebral ischemia. Known coagulopathies should be corrected and oral anticoagulation reversed, but there is no evidence for the routine transfusion of platelets in patients taking aspirin or clopidogrel...
April 2011: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/20048676/intensive-care-unit-acquired-weakness
#4
REVIEW
Richard D Griffiths, Jesse B Hall
OBJECTIVE: Severe weakness is being recognized as a complication that impacts significantly on the pace and degree of recovery and return to former functional status of patients who survive the organ failures that mandate life-support therapies such as mechanical ventilation. Despite the apparent importance of this problem, much remains to be understood about its incidence, causes, prevention, and treatment. DESIGN: Review from literature and an expert round-table...
March 2010: Critical Care Medicine
https://www.readbyqxmd.com/read/18468545/stroke
#5
REVIEW
Geoffrey A Donnan, Marc Fisher, Malcolm Macleod, Stephen M Davis
Stroke is the second most common cause of death and major cause of disability worldwide. Because of the ageing population, the burden will increase greatly during the next 20 years, especially in developing countries. Advances have occurred in the prevention and treatment of stroke during the past decade. For patients with acute stroke, management in a stroke care unit, intravenous tissue plasminogen activator within 3 h or aspirin within 48 h of stroke onset, and decompressive surgery for supratentorial malignant hemispheric cerebral infarction are interventions of proven benefit; several other interventions are being assessed...
May 10, 2008: Lancet
https://www.readbyqxmd.com/read/16286877/weakness-in-the-icu-guillain-barr%C3%A3-syndrome-myasthenia-gravis-and-critical-illness-polyneuropathy-myopathy
#6
REVIEW
Deborah M Green
BACKGROUND: Weakness in the ICU may be caused by a number of disorders. Guillain-Barré syndrome (GBS) and myasthenia gravis (MG) are examples of conditions that might lead to an ICU admission. The most likely cause of weakness after ICU admission is critical illness polyneuropathy/myopathy (CIP/M). REVIEW SUMMARY: Studies have attempted to determine both clinical and pulmonary function criteria for the proper timing of intubation in severe GBS and MG. Optimizing medical management of patients with GBS, MG, and CIP/M is essential in reducing the high morbidity and mortality associated with these conditions...
November 2005: Neurologist
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