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RPHICUTeaching2016.1-Liver Failure

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11 papers 0 to 25 followers Research Papers used in aid of the in-house ICU registrar teaching programme at Royal Perth Hospital in the first half of 2016.
Hendrik Vilstrup, Piero Amodio, Jasmohan Bajaj, Juan Cordoba, Peter Ferenci, Kevin D Mullen, Karin Weissenborn, Philip Wong
No abstract text is available yet for this article.
August 2014: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
Michael D Leise, John J Poterucha, Patrick S Kamath, W Ray Kim
Hepatic encephalopathy (HE) develops in up to 50% of patients with cirrhosis and is a feature of decompensated cirrhosis. With the goal of reviewing the evidence for treatment and prevention of overt hepatic encephalopathy, pubmed was searched using search terms hepatic encephalopathy AND treatment, limited to human studies from January 1, 2003, through December 1, 2013, and supplemented by key references. The inpatient incidence of HE is approximately 23,000 annually, and management of these patients is common for internists and subspecialists...
February 2014: Mayo Clinic Proceedings
William Bernal, Julia Wendon
No abstract text is available yet for this article.
December 26, 2013: New England Journal of Medicine
Faouzi Saliba, Philippe Ichai, Eric Levesque, Didier Samuel
PURPOSE OF REVIEW: Give an update on the importance of prognostic scores at admission to the ICU for defining short-term outcome in critically ill cirrhotic patients. Highlight the correlation between the development of sepsis and/or organ failure and outcome. RECENT FINDINGS: ICU mortality rate of cirrhotic patients admitted to the ICU ranges from 34 to 69%. Few improvements in the management of these patients occurred during the last decade. Definitive treatment relies mainly on the availability of transplant organs...
April 2013: Current Opinion in Critical Care
Lindsey Koliscak, Lena Maynor
PURPOSE: Published evidence on the incidence and predictors of venous thromboembolism (VTE) in patients with cirrhosis of the liver is reviewed. SUMMARY: The frequently observed phenomenon of elevated International Normalized Ratio (INR) values in patients with cirrhosis has led to a theory of "autoanticoagulation" and the assertion that such patients may not benefit from the VTE risk-reduction therapies routinely used in other groups of hospitalized patients. A literature search identified six reports specifically addressing the issue of VTE risk in patients with cirrhosis...
April 15, 2012: American Journal of Health-system Pharmacy: AJHP
Fin Stolze Larsen, Peter Nissen Bjerring
PURPOSE OF REVIEW: Acute liver failure (ALF) results in a multitude of serious complications that often lead to multi-organ failure. This brief review focuses on the pathophysiological processes in ALF and how to manage these. RECENT FINDINGS: The clinical presentation in ALF ranges from slightly altered conscious level with profound coagulopathy to coma with a catastrophic failure of multiple organs, including uncontrollable cerebral edema and brain death, which is rarely seen in decompensated cirrhosis...
April 2011: Current Opinion in Critical Care
Ali Al-Khafaji, David T Huang
OBJECTIVES: To review the management of complications related to end-stage liver disease in the intensive care unit. The goal of this review is to address topics important to the practicing physician. DATA SOURCES: We performed an organ system-based PubMed literature review focusing on the diagnosis and treatment of critical complications of end-stage liver disease. DATA SYNTHESIS AND FINDINGS: When available, preferential consideration was given to randomized controlled trials...
May 2011: Critical Care Medicine
Guadalupe Garcia-Tsao, Jaime Bosch
No abstract text is available yet for this article.
March 4, 2010: New England Journal of Medicine
James F Trotter
PURPOSE OF REVIEW: Acute liver failure is an uncommon condition affecting about 2500 patients each year in the United States. Optimal medical management in the ICU is one of the more important factors impacting survival with or without liver transplantation. This review focuses on the practical aspects of the management of patients with acute liver failure in the ICU. RECENT FINDINGS: The important topics of fluid disturbances, role of the liver biopsy, administration of N-acetylcysteine, role of hypothermic therapy and management of intracranial hypertension, coagulopathy and infection are discussed...
April 2009: Current Opinion in Critical Care
Roberto Rodríguez-Roisin, Michael J Krowka
No abstract text is available yet for this article.
May 29, 2008: New England Journal of Medicine
Guadalupe Garcia-Tsao, Arun J Sanyal, Norman D Grace, William Carey
No abstract text is available yet for this article.
September 2007: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
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