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12 papers 0 to 25 followers
Christian Gratzke, Neil Barber, Mark J Speakman, Richard Berges, Ulrich Wetterauer, Damien Greene, Karl-Dietrich Sievert, Christopher R Chapple, Jacob M Patterson, Lasse Fahrenkrug, Martin Schoenthaler, Jens Sonksen
OBJECTIVES: To compare prostatic urethral lift (PUL) with transurethral resection of the prostate (TURP) with regard to symptoms, recovery experience, sexual function, continence, safety, quality of life, sleep and overall patient perception. PATIENTS AND METHODS: A total of 80 patients with lower urinary tract symptoms attributable to benign prostatic hyperplasia (BPH) were enrolled in a prospective, randomized, controlled, non-blinded study conducted at 10 European centres...
May 2017: BJU International
Naykky Singh Ospina, Juan P Brito, Spyridoula Maraka, Ana E Espinosa de Ycaza, Rene Rodriguez-Gutierrez, Michael R Gionfriddo, Ana Castaneda-Guarderas, Khalid Benkhadra, Alaa Al Nofal, Patricia Erwin, John C Morris, M Regina Castro, Victor M Montori
PURPOSE: To systematically appraise and summarize the available evidence about the diagnostic accuracy of ultrasound-guided fine needle aspiration biopsy (USFNA) for thyroid malignancy, and to explore the integration of these estimates with the probability of thyroid malignancy before USFNA. METHODS: A comprehensive search of multiple databases from each database's inception to August 2014 was performed. Eligible studies included those that evaluated patients with thyroid nodules who underwent USFNA and subsequent evaluation by histopathology or long-term follow-up...
September 2016: Endocrine
Louis M Capecci, Elan Jeremitsky, R Stephen Smith, Frances Philp
BACKGROUND: Nonoperative management (NOM) for blunt splenic injury (BSI) is well-established. Angiography (ANGIO) has been shown to improve success rates with NOM. Protocols for NOM are not standardized and vary widely between centers. We hypothesized that trauma centers that performed ANGIO at a greater rate would demonstrate decreased rates of splenectomy compared with trauma centers that used ANGIO less frequently. METHODS: A large, multicenter, statewide database (Pennsylvania Trauma Systems Foundation) from 2007 to 2011 was used to generate the study cohort of patients with BSI (age ≥ 13)...
October 2015: Surgery
Mackenzie R Cook, Kelly A Fair, Jennifer Burg, Lindsay Cattin, Arvin Gee, Saman Arbabi, Martin Schreiber
BACKGROUND: Cirrhosis may be a risk factor for mortality following blunt splenic injury (BSI) and it predicts the need for an operative intervention. METHODS: We performed a case-control study at 3 level 1 trauma centers. Comparisons were made with chi-square test, Wilcoxon rank-sum test, and binary logistic regression, and stratified by propensity for splenectomy. Data are presented as odds ratios (ORs) and 95% confidence intervals (95% CIs). RESULTS: Mortality was 27% (21/77) and cirrhosis was a strong risk factor for death (OR 8...
May 2015: American Journal of Surgery
Sigurdur Y Kristinsson, Gloria Gridley, Robert N Hoover, David Check, Ola Landgren
Although preservation of the spleen following abdominal trauma and spleen-preserving surgical procedures have become gold standards, about 22,000 splenectomies are still conducted annually in the USA. Infections, mostly by encapsulated organisms, are the most well-known complications following splenectomy. Recently, thrombosis and cancer have become recognized as potential adverse outcomes post-splenectomy. Among more than 4 million hospitalized USA veterans, we assessed incidence and mortality due to infections, thromboembolism, and cancer including 8,149 cancer-free veterans who underwent splenectomy with a follow-up of up to 27 years...
February 2014: Haematologica
Francesco Zaja, Wilma Barcellini, Silvia Cantoni, Monica Carpenedo, Giuseppe Caparrotti, Valentina Carrai, Nicola Di Renzo, Cristina Santoro, Massimo Di Nicola, Dino Veneri, Federico Simonetti, Anna M Liberati, Valeria Ferla, Francesca Paoloni, Enrico Crea, Stefano Volpetti, Enrica Tuniz, Renato Fanin
In patients with immune thrombocytopenia (ITP) refractory to corticosteroids and intravenous immunoglobulins (IVIG), splenectomy may result at higher risk of peri-operative complications and, for this reason, potentially contraindicated. The thrombopoietin receptor agonists (TPO-RAs) romiplostim and eltrombopag have shown high therapeutic activity in primary ITP, but data of efficacy and safety regarding their use in preparation for splenectomy are missing. Thirty-one adult patients, median age 50 years, with corticosteroids and/or IVIG refractory persistent and chronic ITP who were treated with TPO-RAs (romiplostim= 24; eltrombopag= 7) with the aim to increase platelet count and allow a safer execution of splenectomy were retrospectively evaluated...
May 2016: American Journal of Hematology
Yaron Ehrlich, Mary J Brames, Stephen D W Beck, Richard S Foster, Lawrence H Einhorn
PURPOSE: Controversy arises regarding the optimal management of patients with nonseminomatous germ cell tumor (NSGCT) who achieve a serologic and radiographic complete remission (CR) to systemic chemotherapy. Some authors recommend postchemotherapy retroperitoneal lymph node dissection (PC-RPLND), whereas others omit surgery and observe these patients. In an attempt to address this question, we report the long-term follow-up of patients treated at Indiana University who were observed without PC-RPLND...
February 1, 2010: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Lora Melman, Riad Azar, Kathleen Beddow, L Michael Brunt, Valerie J Halpin, J Christopher Eagon, Margaret M Frisella, Steven Edmundowicz, Sreenivasa Jonnalagadda, Brent D Matthews
BACKGROUND: Internal drainage of pancreatic pseudocysts can be accomplished by traditional open or minimally invasive laparoscopic or endoscopic approaches. This study aimed to evaluate the primary and overall success rates and clinical outcomes after laparoscopic, endoscopic, and open pancreatic cystgastrostomy for pancreatic pseudocysts. METHODS: Records of 83 patients undergoing laparoscopic (n = 16), endoscopic (n = 45), and open (n = 22) pancreatic cystgastrostomy were analyzed on an intention-to-treat basis...
February 2009: Surgical Endoscopy
Usama Ahmed Ali, Vincent B Nieuwenhuijs, Casper H van Eijck, Hein G Gooszen, Ronald M van Dam, Olivier R Busch, Marcel G W Dijkgraaf, Femke A Mauritz, Sjoerd Jens, Jay Mast, Harry van Goor, Marja A Boermeester
OBJECTIVE: To evaluate the effect of timing of surgery on the long-term clinical outcome of surgery in chronic pancreatitis (CP). DESIGN: Cohort study with long-term follow-up. SETTING: Five specialized academic centers. PATIENTS: Patients with CP treated surgically for pain. INTERVENTIONS: Pancreatic resection and drainage procedures for pain relief. MAIN OUTCOME MEASURES: Pain relief (pain visual analogue score ≤4), pancreatic function, and quality of life...
October 2012: Archives of Surgery
Chi-hua Fang, Deshuai Kong, Xiaojun Wang, Huaizhi Wang, Nan Xiang, Yingfang Fan, Jian Yang, Shi Zheng Zhong
OBJECTIVE: This study aimed to investigate the clinical significance of 3-dimensional (3D) reconstruction of peripancreatic vessels for patients with suspected pancreatic cancer (PC). METHODS: A total of 89 patients with PC were included; 60 patients randomly underwent computed tomographic angiography. Based on the findings of 3D reconstruction of peripancreatic vessels, the appropriate method for individualized tumor resection was determined. These patients were compared with 29 conventionally treated patients with PC...
April 2014: Pancreas
Jan-Werner Poley, Ewout W Steyerberg, Ernst J Kuipers, Jan Dees, Rober Hartmans, Hugo W Tilanus, Peter D Siersema
BACKGROUND: Ingestion of caustic substances often leads to severe morbidity and, frequently, death. This study compared complications and survival for patients who ingested an acidic substance, mainly glacial acetic acid, or an alkaline agent. METHODS: Records for 179 patients hospitalized for ingestion of a caustic agent (85 acid [75 glacial acetic acid], 94 alkali) were reviewed. Mucosal injury, systemic and GI complications, and survival were scored. RESULTS: Outcome was less favorable for patients who ingested acid compared with those who ingested alkali with respect to mucosal injury (median: grade 2 vs...
September 2004: Gastrointestinal Endoscopy
Andrew W Kirkpatrick, Derek J Roberts, Peter D Faris, Chad G Ball, Paul Kubes, Corina Tiruta, Zhengwen Xiao, Jessalyn K Holodinsky, Paul B McBeth, Christopher J Doig, Craig N Jenne
OBJECTIVE: To determine whether active negative pressure peritoneal therapy with the ABThera temporary abdominal closure device reduces systemic inflammation after abbreviated laparotomy. BACKGROUND: Excessive systemic inflammation after abdominal injury or intra-abdominal sepsis is associated with poor outcomes. METHODS: We conducted a single-center, randomized controlled trial. Forty-five adults with abdominal injury (46.7%) or intra-abdominal sepsis (52...
July 2015: Annals of Surgery
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