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Heart

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113 papers 100 to 500 followers
https://www.readbyqxmd.com/read/29329384/plaque-erosion-a-new-in-vivo-diagnosis-and-a-potential-major-shift-in-the-management-of-patients-with-acute-coronary-syndromes
#1
Ramon A Partida, Peter Libby, Filippo Crea, Ik-Kyung Jang
Pathology and in vivo imaging studies have identified superficial plaque erosion as a frequent and important mechanism underlying acute coronary syndromes (ACS). In contrast with plaque rupture, the pathophysiological mechanisms leading to plaque erosion remain poorly understood. The advent of intravascular imaging techniques, particularly optical coherence tomography, has aided understanding of this mode of ACS in vivo by complementing previous insights from pathology studies. Appreciation of the distinct biological and clinical mechanisms of plaque erosion points to the possibility of tailored management strategies for patients presenting with ACS...
January 9, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29311351/bay%C3%A3-s-syndrome-what-is-it
#2
Adrian Baranchuk, Pelayo Torner, Antoni Bayés de Luna
No abstract text is available yet for this article.
January 9, 2018: Circulation
https://www.readbyqxmd.com/read/29300864/the-year-in-cardiology-2017-arrhythmias-and-cardiac-devices
#3
Cecilia Linde, Jan Steffel
No abstract text is available yet for this article.
January 2, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29300950/the-year-in-cardiology-2017-heart-failure
#4
Lars H Lund, Lars Køber, Karl Swedberg, Frank Ruschitzka
No abstract text is available yet for this article.
January 2, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29277852/comparative-effectiveness-of-implementation-strategies-for-blood-pressure-control-in-hypertensive-patients-a-systematic-review-and-meta-analysis
#5
Katherine T Mills, Katherine M Obst, Wei Shen, Sandra Molina, Hui-Jie Zhang, Hua He, Lisa A Cooper, Jiang He
Background: The prevalence of hypertension is high and is increasing worldwide, whereas the proportion of controlled hypertension is low. Purpose: To assess the comparative effectiveness of 8 implementation strategies for blood pressure (BP) control in adults with hypertension. Data Sources: Systematic searches of MEDLINE and Embase from inception to September 2017 with no language restrictions, supplemented with manual reference searches...
January 16, 2018: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29277252/2017-acc-expert-consensus-decision-pathway-for-optimization-of-heart-failure-treatment-answers-to-10-pivotal-issues-about-heart-failure-with-reduced-ejection-fraction-a-report-of-the-american-college-of-cardiology-task-force-on-expert-consensus-decision-pathways
#6
Clyde W Yancy, James L Januzzi, Larry A Allen, Javed Butler, Leslie L Davis, Gregg C Fonarow, Nasrien E Ibrahim, Mariell Jessup, JoAnn Lindenfeld, Thomas M Maddox, Frederick A Masoudi, Shweta R Motiwala, J Herbert Patterson, Mary Norine Walsh, Alan Wasserman
No abstract text is available yet for this article.
January 16, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29242891/diagnosis-and-treatment-of-hypertension-in-the-2017-acc-aha-guidelines-and-in-the-real-world
#7
John P A Ioannidis
No abstract text is available yet for this article.
January 9, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29229622/regular-tachycardia-with-abnormal-qrs-axis
#8
Rajin Choudhury, Mattias Duytschaever, Sébastien Knecht, Yves Vandekerckhove, Rene Tavernier
No abstract text is available yet for this article.
December 12, 2017: Circulation
https://www.readbyqxmd.com/read/29229783/heartbeat-what-is-the-best-emergency-treatment-for-decompensated-severe-aortic-stenosis
#9
REVIEW
Catherine M Otto
No abstract text is available yet for this article.
January 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29229649/isolated-tricuspid-regurgitation-outcomes-and-therapeutic-interventions
#10
REVIEW
Erin A Fender, Chad J Zack, Rick A Nishimura
Isolated tricuspid regurgitation (TR) can be caused by primary valvular abnormalities such as flail leaflet or secondary annular dilation as is seen in atrial fibrillation, pulmonary hypertension and left heart disease. There is an increasing recognition of a subgroup of patients with isolated TR in the absence of other associated cardiac abnormalities. Left untreated isolated TR significantly worsens survival. Stand-alone surgery for isolated TR is rarely performed due to an average operative mortality of 8%-10% and a paucity of data demonstrating improved survival...
December 11, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29242350/nt-probnp-guided-therapy-in-acute-decompensated-heart-failure-the-prima-ii-randomized-controlled-trial
#11
Susan Stienen, Khibar Salah, Arno H Moons, Adrianus L Bakx, Petra van Pol, Mikael Kortz, João Pedro Ferreira, Irene Marques, Jutta M Schroeder-Tanka, Jan T Keijer, Antoni Bayés-Genis, Jan G P Tijssen, Yigal M Pinto, Wouter E Kok
Background -The concept of natriuretic peptide guidance has been extensively studied in chronic heart failure (HF) patients, with only limited success. The effect of NT-proBNP-guided therapy in acute decompensated HF (ADHF) patients using a relative NT-proBNP target has not been investigated. The aim of this study was to assess whether NT-proBNP-guided therapy of ADHF patients using a relative NT-proBNP target would lead to improved outcome compared with conventional therapy. Methods -We conducted a prospective randomized, controlled trial to study the impact of in-hospital guidance for ADHF treatment by a predefined NT-proBNP target (>30% reduction from admission to discharge) versus conventional treatment...
December 14, 2017: Circulation
https://www.readbyqxmd.com/read/29201914/acute-right-ventricular-dysfunction-in-intensive-care-unit
#12
REVIEW
Juan C Grignola, Enric Domingo
The role of the left ventricle in ICU patients with circulatory shock has long been considered. However, acute right ventricle (RV) dysfunction causes and aggravates many common critical diseases (acute respiratory distress syndrome, pulmonary embolism, acute myocardial infarction, and postoperative cardiac surgery). Several supportive therapies, including mechanical ventilation and fluid management, can make RV dysfunction worse, potentially exacerbating shock. We briefly review the epidemiology, pathophysiology, diagnosis, and recommendations to guide management of acute RV dysfunction in ICU patients...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28302287/non-vitamin-k-antagonist-oral-anticoagulants-in-patients-with-atrial-fibrillation-and-valvular-heart-disease
#13
COMPARATIVE STUDY
Giulia Renda, Fabrizio Ricci, Robert P Giugliano, Raffaele De Caterina
BACKGROUND: Valvular heart disease (VHD) and atrial fibrillation (AF) often coexist. Phase III trials comparing non-vitamin K antagonist oral anticoagulants (NOACs) with warfarin excluded patients with moderate/severe mitral stenosis or mechanical heart valves, but variably included patients with other VHD and valve surgeries. OBJECTIVES: This study aimed to determine relative safety and efficacy of NOACs in patients with VHD. METHODS: We performed a meta-analysis of the 4 phase III AF trials of the currently available NOACs versus warfarin in patients with coexisting VHD to assess pooled estimates of relative risk (RR) and 95% confidence intervals (CIs) for stroke/systemic embolic events (SSEE), major bleeding, intracranial hemorrhage (ICH), and all-cause death...
March 21, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29141174/diuretic-treatment-in-heart-failure
#14
REVIEW
David H Ellison, G Michael Felker
New England Journal of Medicine, Volume 377, Issue 20, Page 1964-1975, November 2017.
November 16, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29109197/an-asymptomatic-man-with-an-abnormal-ecg
#15
Juan Carlos Brenes, Carlos Brenes-Pereira, Alfonso Tolentino, Cornel Lupu
No abstract text is available yet for this article.
November 7, 2017: Circulation
https://www.readbyqxmd.com/read/29114008/2017-american-heart-association-focused-update-on-adult-basic-life-support-and-cardiopulmonary-resuscitation-quality-an-update-to-the-american-heart-association-guidelines-for-cardiopulmonary-resuscitation-and-emergency-cardiovascular-care
#16
REVIEW
Monica E Kleinman, Zachary D Goldberger, Thomas Rea, Robert A Swor, Bentley J Bobrow, Erin E Brennan, Mark Terry, Robin Hemphill, Raúl J Gazmuri, Mary Fran Hazinski, Andrew H Travers
Cardiopulmonary resuscitation is a lifesaving technique for victims of sudden cardiac arrest. Despite advances in resuscitation science, basic life support remains a critical factor in determining outcomes. The American Heart Association recommendations for adult basic life support incorporate the most recently published evidence and serve as the basis for education and training for laypeople and healthcare providers who perform cardiopulmonary resuscitation.
January 2, 2018: Circulation
https://www.readbyqxmd.com/read/29084780/mechanisms-consequences-and-prevention-of-coronary-graft-failure
#17
REVIEW
Mario Gaudino, Charalambos Antoniades, Umberto Benedetto, Saswata Deb, Antonino Di Franco, Gabriele Di Giammarco, Stephen Fremes, David Glineur, Juan Grau, Guo-Wei He, Daniele Marinelli, Lucas B Ohmes, Carlo Patrono, John Puskas, Robert Tranbaugh, Leonard N Girardi, David P Taggart
Graft failure occurs in a sizeable proportion of coronary artery bypass conduits. We herein review relevant current evidence to give an overview of the incidence, pathophysiology, and clinical consequences of this multifactorial phenomenon. Thrombosis, endothelial dysfunction, vasospasm, and oxidative stress are different mechanisms associated with graft failure. Intrinsic morphological and functional features of the bypass conduits play a role in determining failure. Similarly, characteristics of the target coronary vessel, such as the severity of stenosis, the diameter, the extent of atherosclerotic burden, and previous endovascular interventions, are important determinants of graft outcome and must be taken into consideration at the time of surgery...
October 31, 2017: Circulation
https://www.readbyqxmd.com/read/27347226/newer-oral-anticoagulants-stroke-prevention-and-pitfalls
#18
Anand Patel, Richard P Goddeau, Nils Henninger
Warfarin is very effective in preventing stroke in patients with atrial fibrillation. However, its use is limited due to fear of hemorrhagic complications, unpredictable anticoagulant effects related to multiple drug interactions and dietary restrictions, a narrow therapeutic window, frequent difficulty maintaining the anticoagulant effect within a narrow therapeutic window, and the need for inconvenient monitoring. Several newer oral anticoagulants have been approved for primary and secondary prevention of stroke in patients with non-valvular atrial fibrillation...
2016: Open Cardiovascular Medicine Journal
https://www.readbyqxmd.com/read/29097297/systematic-review-for-the-2017-aha-acc-hrs-guideline-for-management-of-patients-with-ventricular-arrhythmias-and-the-prevention-of-sudden-cardiac-death-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice
#19
Fred M Kusumoto, Kent R Bailey, Ahmad Sami Chaouki, Abhishek J Deshmukh, Sandeep Gautam, Robert J Kim, Daniel B Kramer, Litsa K Lambrakos, Naseer H Nasser, Dan Sorajja
BACKGROUND: Although large randomized clinical trials have found that primary prevention use of an implantable cardioverter-defibrillator (ICD) improves survival in patients with cardiomyopathy and heart failure symptoms, patients who receive ICDs in practice are often older and have more comorbidities than patients who were enrolled in the clinical trials. In addition, there is a debate among clinicians on the usefulness of electrophysiological study for risk stratification of asymptomatic patients with Brugada syndrome...
October 24, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29083953/pci-strategies-in-patients-with-acute-myocardial-infarction-and-cardiogenic-shock
#20
RANDOMIZED CONTROLLED TRIAL
Holger Thiele, Ibrahim Akin, Marcus Sandri, Georg Fuernau, Suzanne de Waha, Roza Meyer-Saraei, Peter Nordbeck, Tobias Geisler, Ulf Landmesser, Carsten Skurk, Andreas Fach, Harald Lapp, Jan J Piek, Marko Noc, Tomaž Goslar, Stephan B Felix, Lars S Maier, Janina Stepinska, Keith Oldroyd, Pranas Serpytis, Gilles Montalescot, Olivier Barthelemy, Kurt Huber, Stephan Windecker, Stefano Savonitto, Patrizia Torremante, Christiaan Vrints, Steffen Schneider, Steffen Desch, Uwe Zeymer
BACKGROUND: In patients who have acute myocardial infarction with cardiogenic shock, early revascularization of the culprit artery by means of percutaneous coronary intervention (PCI) improves outcomes. However, the majority of patients with cardiogenic shock have multivessel disease, and whether PCI should be performed immediately for stenoses in nonculprit arteries is controversial. METHODS: In this multicenter trial, we randomly assigned 706 patients who had multivessel disease, acute myocardial infarction, and cardiogenic shock to one of two initial revascularization strategies: either PCI of the culprit lesion only, with the option of staged revascularization of nonculprit lesions, or immediate multivessel PCI...
December 21, 2017: New England Journal of Medicine
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