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Alcohol addiction

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4 papers 0 to 25 followers
Bankole A Johnson, Norman Rosenthal, Julie A Capece, Frank Wiegand, Lian Mao, Karen Beyers, Amy McKay, Nassima Ait-Daoud, Giovanni Addolorato, Raymond F Anton, Domenic A Ciraulo, Henry R Kranzler, Karl Mann, Stephanie S O'Malley, Robert M Swift
BACKGROUND: Topiramate can improve drinking outcomes via a hypothesized mechanism of facilitating gamma-aminobutyric acid function and inhibiting glutaminergic pathways in the corticomesolimbic system. We sought to determine whether topiramate's antidrinking effects are bolstered by improvements in physical and psychosocial well-being. METHODS: In a 17-site, 14-week, double-blind, randomized controlled trial, we compared the effects of topiramate (up to 300 mg/d) vs placebo on physical health, obsessional thoughts and compulsions about using alcohol, and psychosocial well-being among 371 alcohol-dependent subjects who received weekly adherence enhancement therapy...
June 9, 2008: Archives of Internal Medicine
Lawrence D Snell, Vijay A Ramchandani, Laura Saba, David Herion, Markus Heilig, David T George, Lutz Pridzun, Anders Helander, Melanie L Schwandt, Monte J Phillips, Paula L Hoffman, Boris Tabakoff
BACKGROUND: Proper ascertainment of the history of alcohol consumption by an individual is an important component of medical diagnosis of disease and influences the implementation of appropriate treatment strategies that include prescription of medication, as well as intervention for the negative physical and social consequences of hazardous/harmful levels of alcohol consumption. Biological (biometric) diagnostic tests that provide information on current and past quantity and frequency of alcohol consumption by an individual, prior to onset of organ damage, continue to be sought...
February 2012: Alcoholism, Clinical and Experimental Research
(no author information available yet)
In 1995, Miller and C'de Baca created a 50-item measure, the Alcohol Education Inventory (AEI), to assess mental health professionals' basic knowledge of alcohol and alcohol problems. The purpose of this study was to update the AEI based on advances in the field since its publication. The AEI-Revised (AEI-R) consists of 13 of the original AEI items, 30 items that were revised and updated, and 7 new items. The AEI-R was administered to 90 mental health trainees with percentage correct ranging from 60% (psychology postdoctoral fellows) to 70% (psychiatry residents)...
July 2009: Journal of Substance Abuse Treatment
Sanaz Majd
No abstract text is available yet for this article.
June 1, 2012: American Family Physician
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