Salvatore De Rosa, Alberto Polimeni, Giovanni De Velli, Micaela Conte, Sabato Sorrentino, Carmen Spaccarotella, Annalisa Mongiardo, Jolanda Sabatino, Marco Contarini, Ciro Indolfi
The assessment of the left main coronary artery (LMCA) by coronary angiography has several limitations. The fractional flow reserve (FFR) is useful for the functional evaluation of LMCA stenoses. The instantaneous wave-free ratio (iFR), a resting index, was developed to simplify functional coronary assessment. However, its performance for LMCA stenoses has yet to be explored. The iFR was measured at rest, and the FFR was measured under maximal hyperemia. We calculated that a sample size of 90 lesions would have provided 90% power at a 5% significance level to detect an Area Under the Curve (AUC) < 0...
July 31, 2019: Journal of Clinical Medicine