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Wesley H Self, Carlos G Grijalva, Derek J Williams, Alison Woodworth, Robert A Balk, Sherene Fakhran, Yuwei Zhu, D Mark Courtney, James Chappell, Evan J Anderson, Chao Qi, Grant W Waterer, Christopher Trabue, Anna M Bramley, Seema Jain, Kathryn M Edwards, Richard G Wunderink
BACKGROUND: Predicting the need for intensive care among adults with community-acquired pneumonia (CAP) remains challenging. METHODS: Using a multicenter prospective cohort study of adults hospitalized with CAP, we evaluated the association of serum procalcitonin (PCT) concentration at hospital presentation with the need for invasive respiratory or vasopressor support (IRVS), or both, within 72 h. Logistic regression was used to model this association, with results reported as the estimated risk of IRVS for a given PCT concentration...
October 2016: Chest
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