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Ketamine

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2 papers 0 to 25 followers
https://www.readbyqxmd.com/read/25817884/intravenous-subdissociative-dose-ketamine-versus-morphine-for-analgesia-in-the-emergency-department-a-randomized-controlled-trial
#1
RANDOMIZED CONTROLLED TRIAL
Sergey Motov, Bradley Rockoff, Victor Cohen, Illya Pushkar, Antonios Likourezos, Courtney McKay, Emil Soleyman-Zomalan, Peter Homel, Victoria Terentiev, Christian Fromm
STUDY OBJECTIVE: We assess and compare the analgesic efficacy and safety of subdissociative intravenous-dose ketamine with morphine in emergency department (ED) patients. METHODS: This was a prospective, randomized, double-blind trial evaluating ED patients aged 18 to 55 years and experiencing moderate to severe acute abdominal, flank, or musculoskeletal pain, defined as a numeric rating scale score greater than or equal to 5. Patients were randomized to receive ketamine at 0...
September 2015: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/25716117/the-use-of-subdissociative-dose-ketamine-for-acute-pain-in-the-emergency-department
#2
REVIEW
Billy Sin, Theologia Ternas, Sergey M Motov
OBJECTIVES: Ketamine is a well-known anesthetic with its use trailing back to the 1960s. It has antagonistic effects at the N-methyl-d-aspartate receptor. There is emerging literature to suggest the use of subdissociative-dose ketamine (SDDK) for pain reduction. This evidence-based review evaluates the evidence regarding the use of SDDK for acute pain control in the emergency department (ED). METHODS: The MEDLINE and EMBASE databases were searched. Randomized controlled trials (RCTs) that described or evaluated the use of SDDK for acute pain in the ED were included...
March 2015: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
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