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Hematología

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4 papers 0 to 25 followers
https://www.readbyqxmd.com/read/28153383/non-hodgkin-lymphoma
#1
REVIEW
James O Armitage, Randy D Gascoyne, Matthew A Lunning, Franco Cavalli
Lymphomas can affect any organ in the body, present with a wide range of symptoms, and be seen by primary care physicians and physicians from most specialties. They are traditionally divided into Hodgkin's lymphoma (which accounts for about 10% of all lymphomas) and non-Hodgkin lymphoma, which is the topic of this Seminar. Non-Hodgkin lymphoma represents a wide spectrum of illnesses that vary from the most indolent to the most aggressive malignancies. They arise from lymphocytes that are at various stages of development, and the characteristics of the specific lymphoma subtype reflect those of the cell from which they originated...
January 30, 2017: Lancet
https://www.readbyqxmd.com/read/28159390/sickle-cell-disease
#2
REVIEW
Russell E Ware, Mariane de Montalembert, Léon Tshilolo, Miguel R Abboud
Sickle cell disease is a common and life-threatening haematological disorder that affects millions of people worldwide. Abnormal sickle-shaped erythrocytes disrupt blood flow in small vessels, and this vaso-occlusion leads to distal tissue ischaemia and inflammation, with symptoms defining the acute painful sickle-cell crisis. Repeated sickling and ongoing haemolytic anaemia, even when subclinical, lead to parenchymal injury and chronic organ damage, causing substantial morbidity and early mortality. Currently available treatments are limited to transfusions and hydroxycarbamide, although stem cell transplantation might be a potentially curative therapy...
January 31, 2017: Lancet
https://www.readbyqxmd.com/read/27280793/current-approach-for-the-diagnosis-of-aplastic-anemia
#3
Alicia Rovo, Andre Tichelli
The current approach for the diagnosis of aplastic anemia is based on morphology and cytogenetics of hematopoietic cells. The morphological characteristics and similarities with other bone marrow failures disorders represent a real challenge in the differential diagnosis. The evolving better understanding of the subjacent mechanisms involved in bone marrow failures has made a major contribution in the field, however clear delimitation between the different entities need still improvement. New advances in diagnostic technology provide permanently additional information, which might become the basis to solve unmet diagnostic problems...
June 6, 2016: Current Drug Targets
https://www.readbyqxmd.com/read/27083327/transfusion-reactions-prevention-diagnosis-and-treatment
#4
REVIEW
Meghan Delaney, Silvano Wendel, Rachel S Bercovitz, Joan Cid, Claudia Cohn, Nancy M Dunbar, Torunn O Apelseth, Mark Popovsky, Simon J Stanworth, Alan Tinmouth, Leo Van De Watering, Jonathan H Waters, Mark Yazer, Alyssa Ziman
Blood transfusion is one of the most common procedures in patients in hospital so it is imperative that clinicians are knowledgeable about appropriate blood product administration, as well as the signs, symptoms, and management of transfusion reactions. In this Review, we, an international panel, provide a synopsis of the pathophysiology, treatment, and management of each diagnostic category of transfusion reaction using evidence-based recommendations whenever available.
December 3, 2016: Lancet
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