Shefali Miller, Trisha Suppes, Jim Mintz, Gerhard Hellemann, Mark A Frye, Susan L McElroy, Willem A Nolen, Ralph Kupka, Gabriele S Leverich, Heinz Grunze, Lori L Altshuler, Paul E Keck, Robert M Post
OBJECTIVE: DSM-5 introduced the "with mixed features" specifier for major depressive episodes. The authors assessed the prevalence and phenomenology of mixed depression among bipolar disorder patients and qualitatively compared a range of diagnostic thresholds for mixed depression. METHOD: In a naturalistic study, 907 adult outpatients with bipolar disorder participating in the Stanley Foundation Bipolar Network were followed longitudinally across 14,310 visits from 1995 to 2002...
October 1, 2016: American Journal of Psychiatry