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negative pressure pulmonary edema

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By Jason Mann No BS pulmonary critical care fellow
https://www.readbyqxmd.com/read/27063348/negative-pressure-pulmonary-edema
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Mallar Bhattacharya, Richard H Kallet, Lorraine B Ware, Michael A Matthay
Negative-pressure pulmonary edema (NPPE) or postobstructive pulmonary edema is a well-described cause of acute respiratory failure that occurs after intense inspiratory effort against an obstructed airway, usually from upper airway infection, tumor, or laryngospasm. Patients with NPPE generate very negative airway pressures, which augment transvascular fluid filtration and precipitate interstitial and alveolar edema. Pulmonary edema fluid collected from most patients with NPPE has a low protein concentration, suggesting hydrostatic forces as the primary mechanism for the pathogenesis of NPPE...
October 2016: Chest
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