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Cardiología

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67 papers 25 to 100 followers EKG
https://www.readbyqxmd.com/read/28432473/vasopressin-and-vasopressin-antagonists-in-heart-failure
#1
Julie K Vishram-Nielsen, Finn Gustafsson
Despite the introduction of multiple new pharmacological agents over the past three decades in the field of heart failure (HF), overall prognosis remains poor. Hyponatremia is prevalent in HF patients and has been suggested as a contributor to poor response to standard therapy. Elevated levels of arginine vasopressin (AVP), a peptide hormone produced in the hypothalamus, play a role in development of hyponatremia, and AVP and its surrogate, copeptin, are related to changes in osmolality, hemodynamics, neuro-hormones as well as in overall outcome in HF patients...
April 22, 2017: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/28416525/treatment-of-patients-with-atrial-fibrillation-and-heart-failure-with-reduced-ejection-fraction
#2
REVIEW
Atul Verma, Jonathan M Kalman, David J Callans
Atrial fibrillation (AF) and heart failure with reduced ejection fraction (HFrEF) frequently coexist, and each complicates the course and treatment of the other. Recent population-based studies have demonstrated that the 2 conditions together increase the risk of stroke, heart failure hospitalization, and all-cause mortality, especially soon after the clinical onset of AF. Guideline-directed pharmacological therapy for HFrEF is important; however, although there are various treatment modalities for AF, there is no clear consensus on how best to treat AF with concomitant HFrEF...
April 18, 2017: Circulation
https://www.readbyqxmd.com/read/28357786/the-real-role-of-%C3%AE-blockers-in-daily-cardiovascular-therapy
#3
REVIEW
Csaba András Dézsi, Veronika Szentes
The role of β-adrenoceptor antagonists (β-blockers) in cardiovascular therapy has been subject to diverse trends and changes over the decades. With the advent of a wide variety of excellent drugs for the treatment of antihypertension, β-blockers have been relegated from the first-line treatment of essential hypertension. However, they remain the drugs of first choice in recommendations from the respective medical societies for heart failure, coronary artery disease, and atrial fibrillation as well as in hypertension complicated with heart failure, angina pectoris, or prior myocardial infarction...
March 29, 2017: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/22958960/third-universal-definition-of-myocardial-infarction
#4
Kristian Thygesen, Joseph S Alpert, Allan S Jaffe, Maarten L Simoons, Bernard R Chaitman, Harvey D White, Kristian Thygesen, Joseph S Alpert, Harvey D White, Allan S Jaffe, Hugo A Katus, Fred S Apple, Bertil Lindahl, David A Morrow, Bernard R Chaitman, Peter M Clemmensen, Per Johanson, Hanoch Hod, Richard Underwood, Jeroen J Bax, Jeroen J Bonow, Fausto Pinto, Raymond J Gibbons, Keith A Fox, Dan Atar, L Kristin Newby, Marcello Galvani, Christian W Hamm, Barry F Uretsky, Ph Gabriel Steg, William Wijns, Jean-Pierre Bassand, Phillippe Menasche, Jan Ravkilde, E Magnus Ohman, Elliott M Antman, Lars C Wallentin, Paul W Armstrong, Maarten L Simoons, James L Januzzi, Markku S Nieminen, Mihai Gheorghiade, Gerasimos Filippatos, Russell V Luepker, Stephen P Fortmann, Wayne D Rosamond, Dan Levy, David Wood, Sidney C Smith, Dayi Hu, Jose-Luis Lopez-Sendon, Rose Marie Robertson, Douglas Weaver, Michal Tendera, Alfred A Bove, Alexander N Parkhomenko, Elena J Vasilieva, Shanti Mendis, Jeroen J Bax, Helmut Baumgartner, Claudio Ceconi, Veronica Dean, Christi Deaton, Robert Fagard, Christian Funck-Brentano, David Hasdai, Arno Hoes, Paulus Kirchhof, Juhani Knuuti, Philippe Kolh, Theresa McDonagh, Cyril Moulin, Bogdan A Popescu, Zeljko Reiner, Udo Sechtem, Per Anton Sirnes, Michal Tendera, Adam Torbicki, Alec Vahanian, Stephan Windecker, Joao Morais, Carlos Aguiar, Wael Almahmeed, David O Arnar, Fabio Barili, Kenneth D Bloch, Ann F Bolger, Hans Erik Botker, Biykem Bozkurt, Raffaele Bugiardini, Christopher Cannon, James de Lemos, Franz R Eberli, Edgardo Escobar, Mark Hlatky, Stefan James, Karl B Kern, David J Moliterno, Christian Mueller, Aleksandar N Neskovic, Burkert Mathias Pieske, Steven P Schulman, Robert F Storey, Kathryn A Taubert, Pascal Vranckx, Daniel R Wagner
No abstract text is available yet for this article.
October 16, 2012: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28359519/pulmonary-hypertension-in-heart-failure-pathophysiology-pathobiology-and-emerging%C3%A2-clinical%C3%A2-perspectives
#5
REVIEW
Marco Guazzi, Robert Naeije
Pulmonary hypertension is a common hemodynamic complication of heart failure. Interest in left-sided pulmonary hypertension has increased remarkably in recent years because its development and consequences for the right heart are now seen as mainstay abnormalities that begin in the early stages of the disease and bear unfavorable prognostic insights. However, some knowledge gaps limit our ability to influence this complex condition. Accordingly, attention is now focused on: 1) establishing a definitive consensus for a hemodynamic definition, perhaps incorporating exercise and fluid challenge; 2) implementing the limited data available on the pathobiology of lung capillaries and small arteries; 3) developing standard methods for assessing right ventricular function and, hopefully, its coupling to pulmonary circulation; and 4) searching for effective therapies that may benefit lung vessels and the remodeled right ventricle...
April 4, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28346238/management-of-hypertension-in-2017-targets-and-therapies
#6
Monica Ahluwalia, Sripal Bangalore
PURPOSE OF REVIEW: Approximately one-fourth of the adult population is diagnosed with hypertension, which has been associated with increased cardiovascular morbidity and mortality including cardiovascular death, myocardial infarction, heart failure and stroke. Early detection and treatment is a key and can lead to a significant reduction in cardiovascular morbidity and mortality. RECENT FINDINGS: In this review, we discuss the management and treatment strategies in patients with hypertension in the current era...
March 24, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/28249994/duration-of-dual-antiplatelet-therapy-in-acute-coronary-syndrome
#7
REVIEW
Simon John Wilson, David E Newby, Dana Dawson, John Irving, Colin Berry
Despite a large volume of evidence supporting the use of dual antiplatelet therapy in patients with acute coronary syndrome, there remains major uncertainty regarding the optimal duration of therapy. Clinical trials have varied markedly in the duration of therapy, both across and within trials. Recent systematic reviews and meta-analyses suggest that shorter durations of dual antiplatelet therapy are superior because the avoidance of atherothrombotic events is counterbalanced by the greater risks of excess major bleeding with apparent increases in all-cause mortality with longer durations...
April 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28315732/2017-aha-acc-focused-update-of-the-2014-aha-acc-guideline-for-the-management-of-patients-with-valvular-heart-disease-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice-guidelines
#8
Rick A Nishimura, Catherine M Otto, Robert O Bonow, Blase A Carabello, John P Erwin, Lee A Fleisher, Hani Jneid, Michael J Mack, Christopher J McLeod, Patrick T O'Gara, Vera H Rigolin, Thoralf M Sundt, Annemarie Thompson
No abstract text is available yet for this article.
March 10, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28338937/association-of-blood-pressure-trajectory-with-mortality-incident-cardiovascular-disease-and-heart-failure-in-the-cardiovascular-health-study
#9
Christopher C Smitson, Rebecca Scherzer, Michael G Shlipak, Bruce M Psaty, Anne B Newman, Mark J Sarnak, Michelle C Odden, Carmen A Peralta
BACKGROUND: Common blood pressure (BP) trajectories are not well established in elderly persons, and their association with clinical outcomes is uncertain. METHODS: We used hierarchical cluster analysis to identify discrete BP trajectories among 4,067 participants in the Cardiovascular Health Study using repeated BP measures from years 0 to 7. We then evaluated associations of each BP trajectory cluster with all-cause mortality, incident cardiovascular disease (CVD, defined as stroke or myocardial infarction) (N = 2,837), and incident congestive heart failure (HF) (N = 3,633) using Cox proportional hazard models...
March 10, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/27126534/constrictive-pericarditis-versus-restrictive%C3%A2-cardiomyopathy
#10
REVIEW
Mario J Garcia
About one-half of the patients with congestive heart failure have preserved left ventricular ejection fraction (HFpEF). Although the etiology of HFpEF is most commonly related to long-standing hypertension and atherosclerosis, a significant number of suspected HFpEF patients have a restrictive cardiomyopathy or chronic pericardial disease. Recognizing these syndromes is important because early diagnosis may lead to instituting specific therapy that may prolong survival, improve quality of life, and/or recognize and treat an underlying systemic disorder...
May 3, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27103858/update-on-diagnosis-of-acute-rheumatic-fever-2015-jones-criteria
#11
REVIEW
Ayşe Güler Eroğlu
In the final Jones criteria, different diagnostic criteria were established for the diagnosis of acute rheumatic fever for low risk and moderate-high risk populations. Turkey was found to be compatible with moderate-high risk populations as a result of regional screenings performed in terms of acute rheumatic fever and rheumatic heart disease. The changes in the diagnostic criteria for low-risk populations include subclinical carditis found on echocardiogram as a major criterion in addition to carditis found clinically and a body temperature of 38...
March 2016: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/28359510/myocarditis-an-intersection-between-genetic-and-acquired-causes-of-human-cardiomyopathy
#12
EDITORIAL
Kirk U Knowlton
No abstract text is available yet for this article.
April 4, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28190577/dilated-cardiomyopathy
#13
REVIEW
Robert G Weintraub, Christopher Semsarian, Peter Macdonald
Dilated cardiomyopathy is defined by the presence of left ventricular dilatation and contractile dysfunction. Genetic mutations involving genes that encode cytoskeletal, sarcomere, and nuclear envelope proteins, among others, account for up to 35% of cases. Acquired causes include myocarditis and exposure to alcohol, drugs and toxins, and metabolic and endocrine disturbances. The most common presenting symptoms relate to congestive heart failure, but can also include circulatory collapse, arrhythmias, and thromboembolic events...
February 9, 2017: Lancet
https://www.readbyqxmd.com/read/25173338/2014-esc-guidelines-on-diagnosis-and-management-of-hypertrophic-cardiomyopathy-the-task-force-for-the-diagnosis-and-management-of-hypertrophic-cardiomyopathy-of-the-european-society-of-cardiology-esc
#14
Perry M Elliott, Aris Anastasakis, Michael A Borger, Martin Borggrefe, Franco Cecchi, Philippe Charron, Albert Alain Hagege, Antoine Lafont, Giuseppe Limongelli, Heiko Mahrholdt, William J McKenna, Jens Mogensen, Petros Nihoyannopoulos, Stefano Nistri, Petronella G Pieper, Burkert Pieske, Claudio Rapezzi, Frans H Rutten, Christoph Tillmanns, Hugh Watkins
No abstract text is available yet for this article.
October 14, 2014: European Heart Journal
https://www.readbyqxmd.com/read/23609551/treatment-of-acute-and-recurrent-idiopathic-pericarditis
#15
REVIEW
Leonard S Lilly
No abstract text is available yet for this article.
April 23, 2013: Circulation
https://www.readbyqxmd.com/read/24896250/role-of-magnesium-in-cardiovascular-diseases
#16
REVIEW
Dhaval Kolte, Krishnaswami Vijayaraghavan, Sahil Khera, Domenic A Sica, William H Frishman
Magnesium, the fourth most abundant cation in the human body, is involved in several essential physiological, biochemical, and cellular processes regulating cardiovascular function. It plays a critical role in modulating vascular smooth muscle tone, endothelial cell function, and myocardial excitability and is thus central to the pathogenesis of several cardiovascular disorders such as hypertension, atherosclerosis, coronary artery disease, congestive heart failure, and cardiac arrhythmias. This review discusses the vasodilatory, anti-inflammatory, anti-ischemic, and antiarrhythmic properties of magnesium and its current role in the prevention and treatment of cardiovascular disorders...
July 2014: Cardiology in Review
https://www.readbyqxmd.com/read/25888006/clinical-diabetic-cardiomyopathy-a-two-faced-disease-with-restrictive-and-dilated-phenotypes
#17
REVIEW
Petar M Seferović, Walter J Paulus
Diabetes mellitus-related cardiomyopathy (DMCMP) was originally described as a dilated phenotype with eccentric left ventricular (LV) remodelling and systolic LV dysfunction. Recently however, clinical studies on DMCMP mainly describe a restrictive phenotype with concentric LV remodelling and diastolic LV dysfunction. Both phenotypes are not successive stages of DMCMP but evolve independently to respectively heart failure with preserved left ventricular ejection fraction (HFPEF) or reduced left ventricular ejection fraction (HFREF)...
July 14, 2015: European Heart Journal
https://www.readbyqxmd.com/read/25808033/myocardial-metabolism-in-diabetic-cardiomyopathy-potential-therapeutic-targets
#18
REVIEW
Miranda M Sung, Shereen M Hamza, Jason R B Dyck
SIGNIFICANCE: Cardiovascular complications in diabetes are particularly serious and represent the primary cause of morbidity and mortality in diabetic patients. Despite early observations of cardiac dysfunction in diabetic humans, cardiomyopathy unique to diabetes has only recently been recognized. RECENT ADVANCES: Research has focused on understanding the pathogenic mechanisms underlying the initiation and development of diabetic cardiomyopathy. Emerging data highlight the importance of altered mitochondrial function as a major contributor to cardiac dysfunction in diabetes...
June 10, 2015: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/25034069/the-moge-s-classification-of-cardiomyopathy-for-clinicians
#19
REVIEW
Eloisa Arbustini, Navneet Narula, Luigi Tavazzi, Alessandra Serio, Maurizia Grasso, Valentina Favalli, Riccardo Bellazzi, Jamil A Tajik, Robert O Bonow, Robert D Bonow, Valentin Fuster, Jagat Narula
Most cardiomyopathies are familial diseases. Cascade family screening identifies asymptomatic patients and family members with early traits of disease. The inheritance is autosomal dominant in a majority of cases, and recessive, X-linked, or matrilinear in the remaining. For the last 50 years, cardiomyopathy classifications have been based on the morphofunctional phenotypes, allowing cardiologists to conveniently group them in broad descriptive categories. However, the phenotype may not always conform to the genetic characteristics, may not allow risk stratification, and may not provide pre-clinical diagnoses in the family members...
July 22, 2014: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/25565459/stress-induced-cardiomyopathy
#20
REVIEW
Torrey A Boland, Vivien H Lee, Thomas P Bleck
OBJECTIVES: Reversible stress-induced cardiac dysfunction is frequently seen as a complication of a multitude of acute stress states, in particular neurologic injuries. This dysfunction may be difficult to distinguish between that caused by myocardial ischemia and may impact both the treatment strategies and prognosis of the underlying condition. Critical care practitioners should have an understanding of the epidemiology, pathophysiology, clinical characteristics, precipitating conditions, differential diagnosis, and proposed treatments for stress-induced cardiomyopathy...
March 2015: Critical Care Medicine
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