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Psychiatric Biomarkers & Genes: ParuchMD

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By John Paruch Combined training in Internal Medicine-Psychiatry with holistic, evidence-based, preventive approach to implementation and promotion of wellness.
Milutin Kostic, Elisa Canu, Federica Agosta, Ana Munjiza, Ivana Novakovic, Valerija Dobricic, Pilar Maria Ferraro, Vera Miler Jerkovic, Tatjana Pekmezovic, Dusica Lecic Tosevski, Massimo Filippi
In major depressive disorder (MDD), the need to study multiple-gene effect on brain structure is emerging. Our aim was to assess the effect of accumulation of specific SERT, BDNF and COMT gene functional polymorphisms on brain structure in MDD patients. Seventy-seven MDD patients and 66 controls underwent a clinical assessment, genetic testing and MRI scan. Compared with controls, patients were more BDNF-Val homozygotes, COMT-Met carriers and SERT-L' carriers. Thus, subjects were split into three groups: 1...
June 2016: Human Brain Mapping
Natalie Mota, Jennifer A Sumner, Sarah R Lowe, Alexander Neumeister, Monica Uddin, Allison E Aiello, Derek E Wildman, Sandro Galea, Karestan C Koenen, Robert H Pietrzak
No abstract text is available yet for this article.
December 2015: Journal of Clinical Psychiatry
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