collection
MENU ▼
Read by QxMD icon Read
search

GI Cancer

shared collection
4 papers 25 to 100 followers
https://www.readbyqxmd.com/read/27156933/gastric-cancer
#1
REVIEW
Eric Van Cutsem, Xavier Sagaert, Baki Topal, Karin Haustermans, Hans Prenen
Gastric cancer is one of the leading causes of cancer-related death worldwide. Many patients have inoperable disease at diagnosis or have recurrent disease after resection with curative intent. Gastric cancer is separated anatomically into true gastric adenocarcinomas and gastro-oesophageal-junction adenocarcinomas, and histologically into diffuse and intestinal types. Gastric cancer should be treated by teams of experts from different disciplines. Surgery is the only curative treatment. For locally advanced disease, adjuvant or neoadjuvant therapy is usually implemented in combination with surgery...
November 26, 2016: Lancet
https://www.readbyqxmd.com/read/16822992/perioperative-chemotherapy-versus-surgery-alone-for-resectable-gastroesophageal-cancer
#2
RANDOMIZED CONTROLLED TRIAL
David Cunningham, William H Allum, Sally P Stenning, Jeremy N Thompson, Cornelis J H Van de Velde, Marianne Nicolson, J Howard Scarffe, Fiona J Lofts, Stephen J Falk, Timothy J Iveson, David B Smith, Ruth E Langley, Monica Verma, Simon Weeden, Yu Jo Chua, MAGIC Trial Participants
BACKGROUND: A regimen of epirubicin, cisplatin, and infused fluorouracil (ECF) improves survival among patients with incurable locally advanced or metastatic gastric adenocarcinoma. We assessed whether the addition of a perioperative regimen of ECF to surgery improves outcomes among patients with potentially curable gastric cancer. METHODS: We randomly assigned patients with resectable adenocarcinoma of the stomach, esophagogastric junction, or lower esophagus to either perioperative chemotherapy and surgery (250 patients) or surgery alone (253 patients)...
July 6, 2006: New England Journal of Medicine
https://www.readbyqxmd.com/read/26941992/cytoreductive-surgery-and-intraperitoneal-chemotherapy-an-evidence-based-review-past-present-and-future
#3
REVIEW
Ahmed Dehal, J Joshua Smith, Garrett M Nash
Peritoneal carcinomatosis (PC) has historically been considered a terminal condition with merely palliative treatment achieving a survival rate measured in months. Cytoreductive surgery (CyRS) and intraperitoneal chemotherapy (IPC) have emerged as potentially effective regional treatments with the potential for long-term survival in well-selected patients. The fundamentals of CyRS and IPC are patient selection and complete cytoreduction. Since there is now sufficient evidence for the superiority of CyRS and IPC to systemic chemotherapy alone in a highly select group of patients, surgeons and oncologists should be aware of this modality as a potential benefit for patients with PC...
February 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/21431408/cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-improves-survival-of-patients-with-peritoneal-carcinomatosis-from-gastric-cancer-final-results-of-a-phase-iii-randomized-clinical-trial
#4
RANDOMIZED CONTROLLED TRIAL
Xiao-Jun Yang, Chao-Qun Huang, Tao Suo, Lie-Jun Mei, Guo-Liang Yang, Fu-Lin Cheng, Yun-Feng Zhou, Bin Xiong, Yutaka Yonemura, Yan Li
BACKGROUND: This randomized phase III study was to evaluate the efficacy and safety of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) for the treatment of peritoneal carcinomatosis (PC) from gastric cancer. METHODS: Sixty-eight gastric PC patients were randomized into CRS alone (n = 34) or CRS + HIPEC (n = 34) receiving cisplatin 120 mg and mitomycin C 30 mg each in 6000 ml of normal saline at 43 ± 0.5°C for 60-90 min...
June 2011: Annals of Surgical Oncology
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"