collection
https://read.qxmd.com/read/23872175/-big-data-hadoop-and-cloud-computing-in-genomics
#1
JOURNAL ARTICLE
Aisling O'Driscoll, Jurate Daugelaite, Roy D Sleator
Since the completion of the Human Genome project at the turn of the Century, there has been an unprecedented proliferation of genomic sequence data. A consequence of this is that the medical discoveries of the future will largely depend on our ability to process and analyse large genomic data sets, which continue to expand as the cost of sequencing decreases. Herein, we provide an overview of cloud computing and big data technologies, and discuss how such expertise can be used to deal with biology's big data sets...
October 2013: Journal of Biomedical Informatics
https://read.qxmd.com/read/26843812/big-data-application-in-biomedical-research-and-health-care-a-literature-review
#2
REVIEW
Jake Luo, Min Wu, Deepika Gopukumar, Yiqing Zhao
Big data technologies are increasingly used for biomedical and health-care informatics research. Large amounts of biological and clinical data have been generated and collected at an unprecedented speed and scale. For example, the new generation of sequencing technologies enables the processing of billions of DNA sequence data per day, and the application of electronic health records (EHRs) is documenting large amounts of patient data. The cost of acquiring and analyzing biomedical data is expected to decrease dramatically with the help of technology upgrades, such as the emergence of new sequencing machines, the development of novel hardware and software for parallel computing, and the extensive expansion of EHRs...
2016: Biomedical Informatics Insights
https://read.qxmd.com/read/24905493/use-of-artificial-intelligence-as-an-innovative-donor-recipient-matching-model-for-liver-transplantation-results-from-a-multicenter-spanish-study
#3
MULTICENTER STUDY
Javier Briceño, Manuel Cruz-Ramírez, Martín Prieto, Miguel Navasa, Jorge Ortiz de Urbina, Rafael Orti, Miguel-Ángel Gómez-Bravo, Alejandra Otero, Evaristo Varo, Santiago Tomé, Gerardo Clemente, Rafael Bañares, Rafael Bárcena, Valentín Cuervas-Mons, Guillermo Solórzano, Carmen Vinaixa, Angel Rubín, Jordi Colmenero, Andrés Valdivieso, Rubén Ciria, César Hervás-Martínez, Manuel de la Mata
BACKGROUND & AIMS: There is an increasing discrepancy between the number of potential liver graft recipients and the number of organs available. Organ allocation should follow the concept of benefit of survival, avoiding human-innate subjectivity. The aim of this study is to use artificial-neural-networks (ANNs) for donor-recipient (D-R) matching in liver transplantation (LT) and to compare its accuracy with validated scores (MELD, D-MELD, DRI, P-SOFT, SOFT, and BAR) of graft survival...
November 2014: Journal of Hepatology
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