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Multimodal anesthesia

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2 papers 0 to 25 followers
Yun Li, Bin Wang, Li-Li Zhang, Shu-Fang He, Xian-Wen Hu, Gordon T C Wong, Ye Zhang
BACKGROUND: Epidural anesthesia may attenuate the sympathetic hyperactivity and stress response from surgery. In this study, we compared the stress response, hemodynamic variables, and recovery profiles of patients undergoing total IV anesthesia (TIVA) and intraoperative dexmedetomidine with those receiving epidural anesthesia and TIVA. METHODS: Ninety patients undergoing elective open gastrectomy under TIVA were recruited. The dexmedetomidine group (group D, n = 30) received IV dexmedetomidine 0...
April 2016: Anesthesia and Analgesia
Michael C Grant, HeeWon Lee, Andrew J Page, Deborah Hobson, Elizabeth Wick, Christopher L Wu
BACKGROUND: Preoperative gabapentin has been shown to improve postoperative pain and limit reliance on opioid analgesia. On the basis of an alternative mechanism, our group investigated the ability of preoperative gabapentin to prevent postoperative nausea and vomiting (PONV). METHODS: We performed a meta-analysis of trials that reported outcomes on the effect of preoperative gabapentin on PONV end points in patients undergoing general anesthesia. In our primary analysis, we calculated the pooled antiemetic effects of preoperative gabapentin in studies with PONV as the primary end point...
April 2016: Anesthesia and Analgesia
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