collection
MENU ▼
Read by QxMD icon Read
search

Rheumatology

shared collection
5 papers 0 to 25 followers
https://www.readbyqxmd.com/read/26194633/plasmapheresis-therapy-in-anca-associated-vasculitides-a-single-center-retrospective-analysis-of-renal-outcome-and-mortality
#1
David Solar-Cafaggi, Yemil Atisha-Fregoso, Andrea Hinojosa-Azaola
BACKGROUND: The evidence of the benefit of plasmapheresis in renal and survival outcomes in patients with severe manifestations of ANCA-associated vasculitides is inconsistent. PURPOSE: To address whether plasmapheresis is associated with improvement in renal function and survival at 12 months in patients with severe manifestations of ANCA-associated vasculitides. PATIENTS AND METHODS: Single-center retrospective comparative cohort of 24 patients with granulomatosis with polyangiitis or microscopic polyangiitis that received plasmapheresis adjunctive to conventional therapy (steroids and immunosuppressants), matched 1:1 according to age, estimated glomerular filtration rate (eGFR) and disease activity with 24 patients treated with standard treatment only...
October 2016: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/27408429/successful-management-of-refractory-dialysis-independent-wegener-s-granulomatosis-with-combination-of-therapeutic-plasma-exchange-and-rituximab
#2
Sheetal Malhotra, Hari Krishan Dhawan, Ratti Ram Sharma, Neelam Marwaha, Aman Sharma
Wegeners granulomatosis (WG) is an autoimmune, antineutrophil cytoplasmic antibody mediated necrotizing vasculitis involving renal, and upper and lower respiratory systems. Treatment relies on a combination of immunosuppressive drugs and tapering regimen of glucocorticoids. Therapeutic plasma exchange (TPE) has been recognized as a second line treatment. We report the successful use of TPE in combination with rituximab in achieving remission in a patient with WG (dialysis independent) not responding to conventional therapy...
June 2016: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/28602810/apheresis-to-treat-systemic-vasculitis
#3
Julie Moussi-Frances, Marion Sallée, Noémie Jourde-Chiche
Apheresis has been used in the treatment of severe systemic vasculitides, in conjunction with immunosuppressive therapies, for over 40 years. The aim is to rapidly remove autoantibodies or circulating immune complexes from the plasma. The two main indications at present are vasculitis associated with Antineutrophil Cytoplasmic Antibodies (ANCAs) manifesting as severe renal involvement and/or intraalveolar hemorrhage and antiglomerular basement membrane disease (Goodpasture syndrome). The ongoing PEXIVAS randomized controlled trial is assessing plasmapheresis to treat ANCA-associated vasculitis with or without severe renal involvement or intraalveolar hemorrhage...
March 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/29503131/the-treatment-of-anca-associated-rapidly-progressive-glomerulonephritis-and-goodpasture-syndrome-with-therapeutic-apheresis
#4
REVIEW
Suheyla Apaydin
Therapeutic plasma aphresis (plasmapheresis) is one form of treatment that is frequently used in practice of Nephrology. Plasmapheresis is the most important part of the therapies for Goodpasture's syndrome and anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis which are causes of rapidly progressive glomerulonephritis. The reason why the effectiveness of plasmapheresis therapy cannot be clearly demonstrated in renal involvement in these diseases is that it does not appear to be possible to recruit an adequate number of patients and plasmapheresis is not effective in advanced disease if early treatment is not initiated...
February 20, 2018: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/26903390/oral-prednisolone-in-the-treatment-of-acute-gout-a-pragmatic-multicenter-double-blind-randomized-trial
#5
MULTICENTER STUDY
Timothy Hudson Rainer, Chi Hung Cheng, Hein J E M Janssens, Chi Yin Man, Lai Shan Tam, Yu Fai Choi, Wah Hon Yau, Ka Hing Lee, Colin Alexander Graham
BACKGROUND: Two recent double-blind, randomized, controlled trials (RCTs) showed that oral steroids and nonsteroidal anti-inflammatory drugs have similar analgesic effectiveness for management of gout, but the trials had small sample sizes and other methodological limitations. OBJECTIVE: To compare the effectiveness and safety of oral prednisolone versus oral indomethacin in patients presenting to emergency departments (EDs) with acute gout. DESIGN: Multicenter, double-blind, randomized equivalence trial...
April 5, 2016: Annals of Internal Medicine
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"