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ROP

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7 papers 0 to 25 followers
https://www.readbyqxmd.com/read/28501874/screening-tool-for-early-postnatal-prediction-of-retinopathy-of-prematurity-in-preterm-newborns-step-rop
#1
Caroline A Ricard, Christiane E L Dammann, Olaf Dammann
BACKGROUND: Retinopathy of prematurity (ROP) is a disorder of the preterm newborn characterized by neurovascular disruption in the immature retina that may cause visual impairment and blindness. OBJECTIVE: To develop a clinical screening tool for early postnatal prediction of ROP in preterm newborns based on risk information available within the first 48 h of postnatal life. METHODS: Using data submitted to the Vermont Oxford Network (VON) between 1995 and 2015, we created logistic regression models based on infants born <28 completed weeks gestational age...
2017: Neonatology
https://www.readbyqxmd.com/read/27992937/parenteral-fish-oil-lipid-emulsions-in-the-prevention-of-severe-retinopathy-of-prematurity-a-systematic-review-and-meta-analysis
#2
Sakeer Vayalthrikkovil, Rani A Bashir, Yacov Rabi, Harish Amin, Jill-Marie Spence, Helen Lee Robertson, Abhay Lodha
Objective Omega-3 fatty acids are vital for brain and retinal maturation. It is not clear if early use of ω-3 fatty acids in the form of fish-oil lipid emulsions (FLEs) prevents retinopathy of prematurity (ROP) in preterm infants. The aim of this meta-analysis is to evaluate whether early administration of parenteral FLEs reduces ROP requiring laser therapy or severe ROP ≥stage 3 in preterm infants. Methods A literature search was performed to identify studies comparing parenteral FLEs with soybean-based lipid emulsions (SLEs) in preventing ROP...
June 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28087723/prophylactic-propranolol-for-prevention-of-rop-and-visual-outcome-at-1%C3%A2-year-prerop-trial
#3
RANDOMIZED CONTROLLED TRIAL
Kishore Pratap Sanghvi, Nandkishor S Kabra, Phalguni Padhi, Umesh Singh, Swarup Kumar Dash, Bhupendra S Avasthi
OBJECTIVE: To evaluate the role of prophylactic propranolol in the prevention of retinopathy of prematurity (ROP) in infants ≤32 weeks of gestational age and their visual outcome at 1 year of corrected gestational age. DESIGN: Randomised double blind placebo controlled trial, parallel group nrolment with allocation ratio of 1:1. SETTINGS: Two level III neonatal intensive care units. PARTICIPANTS: 109 preterm neonates of ≤32 weeks of gestation with postnatal age ≤8 days old...
September 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/27974588/trends-in-the-screening-and-treatment-of-retinopathy-of-prematurity
#4
Rebecca J Vartanian, Cagri G Besirli, John D Barks, Chris A Andrews, David C Musch
OBJECTIVES: To determine the current practice patterns of retinopathy of prematurity (ROP) screening and treatment and the attitudes toward new screening and treatment modalities in level III and level IV NICUs, as reported by medical directors. METHODS: Surveys were mailed to the medical directors of 847 level III NICUs identified in the 2011 American Academy of Pediatrics directory in April 2015. In September 2015, responses were compared with American Academy of Pediatrics guidelines and previous reports...
January 2017: Pediatrics
https://www.readbyqxmd.com/read/27081928/graded-oxygen-saturation-targets-and-retinopathy-of-prematurity-in-extremely-preterm-infants
#5
Rowena Cayabyab, Vasudha Arora, Fiona Wertheimer, Manuel Durand, Rangasamy Ramanathan
BACKGROUND: We compared the incidence of severe retinopathy of prematurity (ROP) and need for laser treatment before and after implementing graded pulse oximeter oxygen saturation (SpO2) targets in extremely preterm infants. Mortality and other secondary outcomes were compared. METHODS: Before 2002, we used 90-94% as the SpO2 target in infants 24(0/7)-27(6/7)wk gestation and birth weight <1,000 g until 35(6/7) wk postmenstrual age (PMA). We implemented graded SpO2 targets based on vaso-obliterative and vaso-proliferative phases of ROP in 2002...
September 2016: Pediatric Research
https://www.readbyqxmd.com/read/27073259/retinopathy-of-prematurity-screening-criteria-in-iran-new-screening-guidelines
#6
Ramak Roohipoor, Reza Karkhaneh, Afsar Farahani, Nazanin Ebrahimiadib, Bobeck Modjtahedi, Akbar Fotouhi, Mehdi Yaseri, Alireza Khodabande, Mohammad Zarei, Marjan Imani Fuladi, Arash Taheri, Mohammad Riazi Esfahani, John Loewenstein
OBJECTIVE: To test the applicability of existing retinopathy of prematurity (ROP) guidelines on Iranian patients and to develop novel ROP screening criteria in Iran. METHODS: Both eyes of 1932 infants born ≤37 weeks of gestation and/or weighting ≤3000 g were included in this prospective cohort study that was conducted across nine neonatal intensive care units and a tertiary eye hospital ROP clinic. The patients were examined for ROP and the need for treatment (type 1 ROP or worse)...
July 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/26932750/anti-vascular-endothelial-growth-factor-vegf-drugs-for-treatment-of-retinopathy-of-prematurity
#7
REVIEW
Mari Jeeva Sankar, Jhuma Sankar, Manisha Mehta, Vishnu Bhat, Renuka Srinivasan
BACKGROUND: Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis in fetal life. Recently, researchers have attempted to use anti-VEGF agents for the treatment of retinopathy of prematurity (ROP), a vasoproliferative disorder. There is currently uncertainty regarding the safety and efficacy of these agents in preterm infants with ROP. OBJECTIVES: To evaluate the efficacy and safety of anti-VEGF drugs when used either as monotherapy, i.e. without concomitant cryotherapy or laser therapy or in combination with planned cryo/laser therapy in preterm infants with type 1 ROP (defined as zone I any stage with plus disease, zone I stage 3 with or without plus disease or zone II stage 2 or 3 with plus disease)...
2016: Cochrane Database of Systematic Reviews
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