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Less Common, but evidence based treatments: ParuchMD

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13 papers 25 to 100 followers
By John Paruch Combined training in Internal Medicine-Psychiatry with holistic, evidence-based, preventive approach to implementation and promotion of wellness.
https://www.readbyqxmd.com/read/26930527/baseline-blood-levels-of-omega-3-and-depression-remission-a-secondary-analysis-of-data-from-a-placebo-controlled-trial-of-omega-3-supplements
#1
Robert M Carney, Brian C Steinmeyer, Kenneth E Freedland, Eugene H Rubin, Michael W Rich, William S Harris
OBJECTIVE: Depression is associated with low red blood cell (RBC) levels of 2 omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), suggesting that omega-3 supplements might improve depression. However, clinical trials have produced mixed results. The purpose of this secondary analysis of data from a randomized controlled trial was to determine whether baseline blood levels of omega-3, which are known to vary widely among individuals, predict depression outcomes...
February 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/26981142/assessment-of-cardiovascular-parameters-during-meditation-with-mental-targeting-in-varsity-swimmers
#2
Tyvin A Rich, Robert Pfister, John Alton, David Gerdt, Martin Baruch
Introduction. Athletes who develop an immunosuppressed state because of intensive training get upper respiratory infections (URIs) and may respond to meditation. Reflective exercise (RE), a westernized form of Qigong, combines meditation, breathing, and targeted mental attention to an internal pulsatile sensation, previously shown to protect varsity swimmers from URIs during the height of training. We report here the evaluation of cardiovascular parameters measured during meditation combined with targeted imagery (interoception) in a cohort of varsity swimmers taught RE...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/26957941/effects-of-short-term-docosahexaenoic-acid-supplementation-on-markers-of-inflammation-after-eccentric-strength-exercise-in-women
#3
Katherine E Corder, Katherine R Newsham, Jennifer L McDaniel, Uthayashanker R Ezekiel, Edward P Weiss
The omega-3 fatty acid docosahexaenoic acid (DHA) has anti-inflammatory and anti-nociceptive (pain inhibiting) effects. Because strenuous exercise often results in local inflammation and pain, we hypothesized that DHA supplementation attenuates the rise in markers of local muscle inflammation and delayed onset muscle soreness (DOMS) that occur after eccentric strength exercise. Twenty-seven, healthy women (33 ± 2 y, BMI 23.1±1.0 kg·m(-2)) were randomized to receive 9d of 3000 mg/d DHA or placebo in a double-blind fashion...
March 2016: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/26892121/chelation-therapy-in-the-treatment-of-cardiovascular-diseases
#4
REVIEW
Awais Ibad, Rabia Khalid, Paul D Thompson
OBJECTIVE: We examined the effect of chelation therapy on cardiovascular diseases (CVDs). BACKGROUND: EDTA is a chelating agent that binds to metals including calcium and facilitates their excretion. Chelation with EDTA is recommended by some practitioners to treat CVD with the hypothesis that reducing calcium reduces atherosclerotic calcification of arteries. However, chelation therapy has not been approved by the Food and Drug Administration, and its effectiveness is unclear...
January 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/26445680/successful-treatment-of-binge-eating-disorder-with-combination-phentermine-topiramate-extended-release
#5
Anna I Guerdjikova, Angela Fitch, Susan L McElroy
No abstract text is available yet for this article.
2015: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/26362282/predicting-a-response-to-antibiotics-in-patients-with-the-irritable-bowel-syndrome
#6
Rafid Kasir, Salam Zakko, Philip Zakko, Michael Adler, Aaron Lee, Sachin Dhingra, Cecile Guttermuth
BACKGROUND: Antibiotics for presumed small intestinal bacterial overgrowth have been shown to improve irritable bowel syndrome symptoms in at least 40% of subjects. A lactulose breath test for small intestinal bacterial overgrowth has been used to select patients who will respond. However, its predictive value, using the classic definition of a positive lactulose breath test, has been disappointing. AIMS: We conducted a retrospective evaluation to study characteristics of the lactulose breath test that may be predictive of a response to antibiotics in patients with the irritable bowel syndrome...
March 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/26278025/breath-hydrogen-and-methane-are-associated-with-intestinal-symptoms-in-patients-with-chronic-pancreatitis
#7
Dae Bum Kim, Chang-Nyol Paik, Hea Jung Sung, Woo Chul Chung, Kang-Moon Lee, Jin-Mo Yang, Myung-Gyu Choi
BACKGROUNDS: The bacterial overgrowth might be associated with chronic pancreatitis. This study was to evaluate the prevalence and characteristics of small intestinal bacterial overgrowth (SIBO) in patients with chronic pancreatitis. METHODS: 36 patients with chronic pancreatitis and 49 healthy controls undergoing the hydrogen (H2)-methane (CH4) lactulose breath test (LBT) were reviewed. The LBT positivity (+) indicating the presence of SIBO, gas types, bowel symptom questionnaire, laboratory and radiologic results were surveyed...
September 2015: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/26208967/taurine-the-appeal-of-a-safe-amino-acid-for-skeletal-muscle-disorders
#8
REVIEW
Annamaria De Luca, Sabata Pierno, Diana Conte Camerino
Taurine is a natural amino acid present as free form in many mammalian tissues and in particular in skeletal muscle. Taurine exerts many physiological functions, including membrane stabilization, osmoregulation and cytoprotective effects, antioxidant and anti-inflammatory actions as well as modulation of intracellular calcium concentration and ion channel function. In addition taurine may control muscle metabolism and gene expression, through yet unclear mechanisms. This review summarizes the effects of taurine on specific muscle targets and pathways as well as its therapeutic potential to restore skeletal muscle function and performance in various pathological conditions...
2015: Journal of Translational Medicine
https://www.readbyqxmd.com/read/22668858/association-of-mthfr-c677t-polymorphism-with-loneliness-but-not-depression-in-cognitively-normal-elderly-males
#9
Wen-Hsuan Lan, Albert C Yang, Jen-Ping Hwang, Chen-Jee Hong, Ying-Jay Liou, Heng-Liang Yeh, Mu-En Liu, Shih-Jen Tsai
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is involved in folate and homocysteine metabolism, and has been associated with geriatric disorders, including dementia and late-life depression. The present work aimed to investigate the effect of MTHFR C677T polymorphism on the presence of depression and loneliness in cognitively normal male subjects. A total of 323 cognitively normal male subjects were included in this study (mean age=80.6; SD=5.3). Depression was assessed by the Geriatric Depression Scale-Short Form (GDS-SF) and loneliness by UCLA loneliness scales...
July 11, 2012: Neuroscience Letters
https://www.readbyqxmd.com/read/22502624/application-of-the-essential-oil-from-copaiba-copaifera-langsdori-desf-for-acne-vulgaris-a-double-blind-placebo-controlled-clinical-trial
#10
RANDOMIZED CONTROLLED TRIAL
Ary Gomes da Silva, Paula de Freitas Puziol, Roane Nunes Leitao, Tatiana Rafaela Gomes, Rodrigo Scherer, Monica Lacerda Lopes Martins, Aurea Scardua Saade Cavalcanti, Luiz Carlos Cavalcanti
Copaiba oil-resin is widely used in traditional medicine due to its anti-inflammatory, healing, and antiseptic activities. This research aims to extract and evaluate the qualitative and quantitative composition of copaiba essential oil from the oil-resin, and test its effects, after incorporation in a gel applied in volunteers with acne, in a double-blind placebo controlled clinical trial. The essential oil was extracted by steam distillation, and purified by freezing to remove the residual remnant water. The density of the essential oil was gravimetrically determined by weighing 1 mL of liquid at 20 degree C...
March 2012: Alternative Medicine Review: a Journal of Clinical Therapeutic
https://www.readbyqxmd.com/read/22233189/the-combination-very-low-dose-naltrexone-clonidine-in-the-management-of-opioid-withdrawal
#11
RANDOMIZED CONTROLLED TRIAL
Paolo Mannelli, Kathleen Peindl, Li-Tzy Wu, Ashwin A Patkar, David A Gorelick
BACKGROUND: The management of withdrawal absorbs substantial clinical efforts in opioid dependence (OD). The real challenge lies in improving current pharmacotherapies. Although widely used, clonidine causes problematic adverse effects and does not alleviate important symptoms of opioid withdrawal, alone or in combination with the opioid antagonist naltrexone. Very low-dose naltrexone (VLNTX) has been shown to attenuate withdrawal intensity and noradrenaline release following opioid agonist taper, suggesting a combination with clonidine may result in improved safety and efficacy...
May 2012: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/22214254/the-effects-of-l-theanine-suntheanine%C3%A2-on-objective-sleep-quality-in-boys-with-attention-deficit-hyperactivity-disorder-adhd-a-randomized-double-blind-placebo-controlled-clinical-trial
#12
RANDOMIZED CONTROLLED TRIAL
Michael R Lyon, Mahendra P Kapoor, Lekh R Juneja
INTRODUCTION: The purpose of this study was to investigate the efficacy and safety of L-theanine as an aid to the improvement of objectively measured sleep quality in a population of 98 male children formally diagnosed with attention-deficit/hyperactivity disorder (ADHD). METHODS: A randomized, double-blind, placebo-controlled trial was conducted involving boys, ages 8-12 years, who had been previously diagnosed with ADHD. An experienced physician confirmed the diagnosis of ADHD in each subject...
December 2011: Alternative Medicine Review: a Journal of Clinical Therapeutic
https://www.readbyqxmd.com/read/21851312/application-of-liposome-encapsulation-technique-to-improve-anti-carcinoma-effect-of-resveratrol
#13
Xin-Yi Lu, Song Hu, Yi Jin, Li-Yan Qiu
AIM: The promising anti-tumor effect of resveratrol (RES) has aroused much interest in recent years, but its clinical application was seriously hindered due to its poor solubility in water. The aim of this study was to improve the water solubility of RES by liposome encapsulation technique for effective tumor treatment. METHODS: This study develops two liposomal formulations to solubilize RES by reverse-phase evaporation method with or without poly(ethylene glycol-2000)-grafted distearolyl phosphatidylethanolamine (DSPE-PEG(2000))...
March 2012: Drug Development and Industrial Pharmacy
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