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Pediatric

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7 papers 0 to 25 followers
By Roberto Garay-Cabada Pediatrics , Fellow in pediatric Pulmonology
https://www.readbyqxmd.com/read/27788026/trial-of-amitriptyline-topiramate-and-placebo-for-pediatric-migraine
#1
Scott W Powers, Christopher S Coffey, Leigh A Chamberlin, Dixie J Ecklund, Elizabeth A Klingner, Jon W Yankey, Leslie L Korbee, Linda L Porter, Andrew D Hershey
Background Which, medication, if any, to use to prevent the headache of pediatric migraine has not been established. Methods We conducted a randomized, double-blind, placebo-controlled trial of amitriptyline (1 mg per kilogram of body weight per day), topiramate (2 mg per kilogram per day), and placebo in children and adolescents 8 to 17 years of age with migraine. Patients were randomly assigned in a 2:2:1 ratio to receive one of the medications or placebo. The primary outcome was a relative reduction of 50% or more in the number of headache days in the comparison of the 28-day baseline period with the last 28 days of a 24-week trial...
October 27, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27430884/blood-pressure-percentile-charts-to-identify-high-or-low-blood-pressure-in-children
#2
Ashish Banker, Cynthia Bell, Monesha Gupta-Malhotra, Joshua Samuels
BACKGROUND: The goal was to develop familiar blood pressure (BP) charts representing BP percentile curves similar to CDC growth charts to improve screening of both high and low BP in children. METHODS: Since height accounts for substantially more BP variability than age and is a more direct measure of body size and maturation in children, height-specific BP percentile curves were drawn separately for males and females. We used the 2004 Fourth Report data source and equations to calculate the BP threshold value for each gender and 5 cm height group...
2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27380464/duration-of-infant-protection-against-influenza-illness-conferred-by-maternal-immunization-secondary-analysis-of-a-randomized-clinical-trial
#3
Marta C Nunes, Clare L Cutland, Stephanie Jones, Andrea Hugo, Richard Madimabe, Eric A F Simões, Adriana Weinberg, Shabir A Madhi
IMPORTANCE: Influenza immunization of women during pregnancy protects the young infants against influenza illness. The duration of this protection remains unclear. OBJECTIVE: To evaluate the duration of infant protection conferred by maternal immunization and its association with transplacental antibody transfer. DESIGN, SETTING, AND PARTICIPANTS: Infants born to women who participated in a randomized, double-blind, placebo-controlled clinical trial in 2011 and 2012 on the safety, immunogenicity, and efficacy of trivalent inactivated influenza vaccine (IIV3) during pregnancy were followed up during the first 6 months of life for polymerase chain reaction (PCR)-confirmed influenza illness...
September 1, 2016: JAMA Pediatrics
https://www.readbyqxmd.com/read/27020793/acute-otitis-media-and-other-complications-of-viral-respiratory-infection
#4
Tasnee Chonmaitree, Rocio Trujillo, Kristofer Jennings, Pedro Alvarez-Fernandez, Janak A Patel, Michael J Loeffelholz, Johanna Nokso-Koivisto, Reuben Matalon, Richard B Pyles, Aaron L Miller, David P McCormick
BACKGROUND: Viral upper and lower respiratory tract infections (URI, LRI) are common in infants. We determined the prevalence of viral URI and its complications, including acute otitis media (AOM) and LRI, and assessed the effect of bacterial-viral interactions, and genetic and environmental risks on AOM development. METHODS: Healthy infants were enrolled from near birth and followed to the first episode of AOM up to 12 months of age. Nasopharyngeal specimens were collected at monthly intervals (months 1-6, 9) and during viral URI episodes for bacterial culture and viral polymerase chain reaction studies...
April 2016: Pediatrics
https://www.readbyqxmd.com/read/26991604/serious-complications-in-male-infant-circumcisions-in-scandinavia-indicate-that-this-always-be-performed-as-a-hospital-based-procedure
#5
Gertrud Edler, Inge Axelsson, Gillian M Barker, Susanne Lie, Estelle Naumburg
AIM: More than 7000 male circumcisions are performed in Scandinavia every year. Circumcision is regulated in different ways in Sweden and Denmark and Norway. This study reviewed and described factors associated with complications of circumcision in infant boys in Scandinavia over the last two decades and discussed how these complications could be avoided. METHODS: Data on significant complications following circumcision on boys under the age of one in Scandinavia over the last 20 years were collected...
July 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/26948435/guillain-barr%C3%A3-syndrome
#6
REVIEW
Hugh J Willison, Bart C Jacobs, Pieter A van Doorn
Guillain-Barré syndrome is the most common and most severe acute paralytic neuropathy, with about 100,000 people developing the disorder every year worldwide. Under the umbrella term of Guillain-Barré syndrome are several recognisable variants with distinct clinical and pathological features. The severe, generalised manifestation of Guillain-Barré syndrome with respiratory failure affects 20-30% of cases. Treatment with intravenous immunoglobulin or plasma exchange is the optimal management approach, alongside supportive care...
August 13, 2016: Lancet
https://www.readbyqxmd.com/read/26471383/part-13-neonatal-resuscitation-2015-american-heart-association-guidelines-update-for-cardiopulmonary-resuscitation-and-emergency-cardiovascular-care-reprint
#7
Myra H Wyckoff, Khalid Aziz, Marilyn B Escobedo, Vishal S Kapadia, John Kattwinkel, Jeffrey M Perlman, Wendy M Simon, Gary M Weiner, Jeanette G Zaichkin
No abstract text is available yet for this article.
November 2015: Pediatrics
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