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Chronic antibody mediated rejection

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Kunio Morozumi, Asami Takeda, Yasuhiro Otsuka, Keiji Horike, Norihiko Gotoh, Shunji Narumi, Yoshihiko Watarai, Takaaki Kobayashi
The clinicopathological context of rejection after kidney transplantation was well recognized. Banff conferences greatly contributed to elucidate the pathogenesis and to establish the pathologic criteria of rejection after kidney transplantation. The most important current problem of renal transplantation is de novo donor-specific antibody (DSA) production leading chronic rejection and graft loss. Microvascular inflammation is considered as a reliable pathological marker for antibody-mediated rejection (AMR) in the presence of DSA...
July 2016: Nephrology
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