Epifanio Mondello, Domenico Quattrone, Luigi Cardia, Giuseppe Bova, Raffaella Mallamace, Alessia A Barbagallo, Cristina Mondello, Carmen Mannucci, Martina Di Pietro, Vincenzo Arcoraci, Gioacchino Calapai
Objective: This study aimed to evaluate pain and its symptoms in patients with failed back surgery syndrome (FBSS) refractory to other therapies, treated with a combination of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), in association with spinal cord stimulation (SCS). Settings: Outpatients referred at Pain Unit of San Vincenzo Hospital in Taormina (Italy), between September 2014 and January 2016. Subjects: Eleven FBSS patients diagnosed with neuropathic pain using the Douleur Neuropathique 4 questionnaire and suffering from moderate to severe chronic refractory pain, and undergoing treatment with SCS and a combination of THC/CBD for 12 consecutive months...
2018: Journal of Pain Research