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CHRONIC PAIN SUFFERERS (New More Effective Pain Relieving Medicines or Therapies)

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2 papers 0 to 25 followers
https://www.readbyqxmd.com/read/26283638/understanding-and-predicting-suicidality-using-a-combined-genomic-and-clinical-risk-assessment-approach
#1
A B Niculescu, D F Levey, P L Phalen, H Le-Niculescu, H D Dainton, N Jain, E Belanger, A James, S George, H Weber, D L Graham, R Schweitzer, T B Ladd, R Learman, E M Niculescu, N P Vanipenta, F N Khan, J Mullen, G Shankar, S Cook, C Humbert, A Ballew, M Yard, T Gelbart, A Shekhar, N J Schork, S M Kurian, G E Sandusky, D R Salomon
Worldwide, one person dies every 40 seconds by suicide, a potentially preventable tragedy. A limiting step in our ability to intervene is the lack of objective, reliable predictors. We have previously provided proof of principle for the use of blood gene expression biomarkers to predict future hospitalizations due to suicidality, in male bipolar disorder participants. We now generalize the discovery, prioritization, validation, and testing of such markers across major psychiatric disorders (bipolar disorder, major depressive disorder, schizoaffective disorder, and schizophrenia) in male participants, to understand commonalities and differences...
November 2015: Molecular Psychiatry
https://www.readbyqxmd.com/read/26107922/association-between-obstetric-mode-of-delivery-and-autism-spectrum-disorder-a-population-based-sibling-design-study
#2
Eileen A Curran, Christina Dalman, Patricia M Kearney, Louise C Kenny, John F Cryan, Timothy G Dinan, Ali S Khashan
IMPORTANCE: Because the rates of cesarean section (CS) are increasing worldwide, it is becoming increasingly important to understand the long-term effects that mode of delivery may have on child development. OBJECTIVE: To investigate the association between obstetric mode of delivery and autism spectrum disorder (ASD). DESIGN, SETTING, AND PARTICIPANTS: Perinatal factors and ASD diagnoses based on the International Classification of Diseases, Ninth Revision (ICD-9),and the International Statistical Classification of Diseases, 10th Revision (ICD-10),were identified from the Swedish Medical Birth Register and the Swedish National Patient Register...
September 2015: JAMA Psychiatry
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