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Jonathan A Janiczek, Daniel G Winger, Patrick Coppler, Alexa R Sabedra, Holt Murray, Michael R Pinsky, Jon C Rittenberger, Joshua C Reynolds, Cameron Dezfulian
PURPOSE: To determine which strategy of early post-cardiac arrest hemodynamic resuscitation was associated with best clinical outcomes. We hypothesized that higher mean arterial pressure (MAP) achieved using IV fluids over vasopressors would yield better outcomes. METHODS: Retrospective cohort study of post-cardiac arrest patients between March 2011 and June 2012. Patients successfully resuscitated from cardiac arrest, admitted to an intensive care unit and surviving at least 24 h, were included...
June 2016: Shock
Janice A Tijssen, David K Prince, Laurie J Morrison, Dianne L Atkins, Michael A Austin, Robert Berg, Siobhan P Brown, Jim Christenson, Debra Egan, Preston J Fedor, Ericka L Fink, Garth D Meckler, Martin H Osmond, Kathryn A Sims, James S Hutchison
BACKGROUND: Survival is less than 10% for pediatric patients following out-of-hospital cardiac arrest. It is not known if more time on the scene of the cardiac arrest and advanced life support interventions by emergency services personnel are associated with improved survival. AIM: This study was performed to determine which times on the scene and which prehospital interventions were associated with improved survival. METHODS: We studied patients aged 3 days to 19 years old with out-of-hospital cardiac arrest, using the Resuscitation Outcomes Consortium cardiac arrest database from 11 North American regions, from 2005 to 2012...
September 2015: Resuscitation
Rudolph W Koster
No abstract text is available yet for this article.
December 3, 2015: New England Journal of Medicine
Graham Nichol, Brian Leroux, Henry Wang, Clifton W Callaway, George Sopko, Myron Weisfeldt, Ian Stiell, Laurie J Morrison, Tom P Aufderheide, Sheldon Cheskes, Jim Christenson, Peter Kudenchuk, Christian Vaillancourt, Thomas D Rea, Ahamed H Idris, Riccardo Colella, Marshal Isaacs, Ron Straight, Shannon Stephens, Joe Richardson, Joe Condle, Robert H Schmicker, Debra Egan, Susanne May, Joseph P Ornato
BACKGROUND: During cardiopulmonary resuscitation (CPR) in patients with out-of-hospital cardiac arrest, the interruption of manual chest compressions for rescue breathing reduces blood flow and possibly survival. We assessed whether outcomes after continuous compressions with positive-pressure ventilation differed from those after compressions that were interrupted for ventilations at a ratio of 30 compressions to two ventilations. METHODS: This cluster-randomized trial with crossover included 114 emergency medical service (EMS) agencies...
December 3, 2015: New England Journal of Medicine
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