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Chronic Obstructive Pulmonary Disease: ParuchMD

https://read.qxmd.com/read/18836213/a-4-year-trial-of-tiotropium-in-chronic-obstructive-pulmonary-disease
#1
RANDOMIZED CONTROLLED TRIAL
Donald P Tashkin, Bartolome Celli, Stephen Senn, Deborah Burkhart, Steven Kesten, Shailendra Menjoge, Marc Decramer
BACKGROUND: Previous studies showing that tiotropium improves multiple end points in patients with chronic obstructive pulmonary disease (COPD) led us to examine the long-term effects of tiotropium therapy. METHODS: In this randomized, double-blind trial, we compared 4 years of therapy with either tiotropium or placebo in patients with COPD who were permitted to use all respiratory medications except inhaled anticholinergic drugs. The patients were at least 40 years of age, with a forced expiratory volume in 1 second (FEV(1)) of 70% or less after bronchodilation and a ratio of FEV(1) to forced vital capacity (FVC) of 70% or less...
October 9, 2008: New England Journal of Medicine
https://read.qxmd.com/read/25381699/correlation-between-heart-rate-variability-indexes-and-aerobic-physiological-variables-in-patients-with-copd
#2
JOURNAL ARTICLE
Marceli R Leite, Ercy Mara C Ramos, Carlos A Kalva-Filho, Fernanda Maria M Rodrigues, Ana Paula C F Freire, Guilherme Y Tacao, Alessandra C de Toledo, Michel J CecĂ­lio, Luiz Carlos M Vanderlei, Dionei Ramos
BACKGROUND AND OBJECTIVE: Previous studies have shown a relationship between the level of physical fitness and autonomic variables. However, these relationships have not been investigated in patients with chronic obstructive pulmonary disease (COPD). The objective of this study was to correlate the resting heart rate variability (HRV) indexes with aerobic physiological variables obtained at a maximal exercise test in patients with COPD. METHODS: Thirty-seven patients with COPD (63 (59-70) years; 46 (35...
February 2015: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/24594853/potential-effect-of-6-versus-12-weeks-of-physical-training-on-cardiac-autonomic-function-and-exercise-capacity-in-chronic-obstructive-pulmonary-disease
#3
RANDOMIZED CONTROLLED TRIAL
A Borghi-Silva, R G Mendes, R Trimer, C R Oliveira, G A Fregonezi, V R Resqueti, R Arena, L M Sampaio-Jorge, D Costa
BACKGROUND: Exercise is an important part of chronic obstructive pulmonary disease (COPD) treatment. However, it is not know about the minimum effective time of physical training that could beneficially modify the cardiac autonomic modulation (CAM) and exercise capacity in these patients. AIM: To contrast the potential effects of a physical training program (PTP), for 6 versus 12 weeks, on CAM by linear and nonlinear heart rate variability (HRV) indices and exercise capacity in COPD patients...
April 2015: European Journal of Physical and Rehabilitation Medicine
https://read.qxmd.com/read/24787632/the-effect-of-4-week-rehabilitation-on-heart-rate-variability-and-qtc-interval-in-patients-with-chronic-obstructive-pulmonary-disease
#4
RANDOMIZED CONTROLLED TRIAL
Eva Zupanic, Ina Zivanovic, Jurij Matija Kalisnik, Viktor Avbelj, Mitja Lainscak
Chronic obstructive pulmonary disease negatively affects the autonomic nervous system and increases risks of arrhythmias and sudden cardiac death. Electrocardiogram (ECG) recordings were used to compare parameters of heart rate variability and QTc interval in patients with COPD and healthy individuals. The effects of a 4-week program of rehabilitation in patients with COPD were also evaluated by comparing pre- and post-rehabilitation ECGs with age- and sex-matched control COPD patients not participating in the program...
December 2014: COPD
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