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Whole brain plus srs vs surgery

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2 papers 25 to 100 followers
Matthew P Deek, Sinae Kim, Inaya Ahmed, Bruno S Fang, Wei Zou, Jyoti Malhotra, Joseph Aisner, Salma K Jabbour
OBJECTIVE: The aim of this study is to investigate the impact of missed chemotherapy administrations (MCA) on the prognosis of non-small cell lung cancer (NSCLC) patients treated with definitive chemoradiation therapy (CRT). MATERIALS AND METHODS: In total, 97 patients with NSCLC treated with definitive CRT were assessed for MCA due to toxicities. Logistic regression was used to determine factors associated with MCA. Kaplan-Meier curves, log-rank tests, and Cox Proportional Hazards models were conducted...
April 2018: American Journal of Clinical Oncology
Minesh P Mehta, Manmeet S Ahluwalia
The overall local treatment paradigm of brain metastases, which includes whole-brain radiotherapy (WBRT) and stereotactic radiosurgery (SRS), continues to evolve. Local therapies play an important role in the management of brain metastases. The choice of local therapy depends on factors that involve the patient (performance status, expected survival, and age), the prior treatment history, and the tumor (type and subtype, number, size, location of metastases, and extracranial disease status). Multidisciplinary collaboration is required to facilitate an individualized plan to improve the outcome of disease in patients with this life-limiting complication...
2015: American Society of Clinical Oncology Educational Book
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