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Surgery

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93 papers 500 to 1000 followers
https://www.readbyqxmd.com/read/29374617/efficacy-of-medical-therapies-for-fistulizing-crohn-s-disease-systematic-review-and-meta-analysis
#1
REVIEW
Matthew J Lee, Claire E Parker, Sarah R Taylor, Leonardo Guizzetti, Brian G Feagan, Alan J Lobo, Vipul Jairath
BACKGROUND & AIMS: Fistulas are debilitating complications of Crohn's disease (CD) that affect up to 50% of patients. We conducted a systematic review and meta-analysis of randomized controlled trials to assess the efficacy of treatments for fistulizing CD. METHODS: We searched publication databases from inception through December 13, 2016 for trials comparing the efficacy of a therapeutic agent (single or combination) with placebo or another active therapy in adult patients with any form of fistulizing CD...
January 25, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29306520/guidelines-for-sedation-and-anesthesia-in-gi-endoscopy
#2
Dayna S Early, Jenifer R Lightdale, John J Vargo, Ruben D Acosta, Vinay Chandrasekhara, Krishnavel V Chathadi, John A Evans, Deborah A Fisher, Lisa Fonkalsrud, Joo Ha Hwang, Mouen A Khashab, V Raman Muthusamy, Shabana F Pasha, John R Saltzman, Amandeep K Shergill, Brooks D Cash, John M DeWitt
No abstract text is available yet for this article.
February 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/26211827/aromatase-inhibitors-versus-tamoxifen-in-early-breast-cancer-patient-level-meta-analysis-of-the-randomised-trials
#3
COMPARATIVE STUDY
(no author information available yet)
BACKGROUND: The optimal ways of using aromatase inhibitors or tamoxifen as endocrine treatment for early breast cancer remains uncertain. METHODS: We undertook meta-analyses of individual data on 31,920 postmenopausal women with oestrogen-receptor-positive early breast cancer in the randomised trials of 5 years of aromatase inhibitor versus 5 years of tamoxifen; of 5 years of aromatase inhibitor versus 2-3 years of tamoxifen then aromatase inhibitor to year 5; and of 2-3 years of tamoxifen then aromatase inhibitor to year 5 versus 5 years of tamoxifen...
October 3, 2015: Lancet
https://www.readbyqxmd.com/read/29366842/histologic-factors-associated-with-need-for-surgery-in-patients-with-pedunculated-t1-colorectal-carcinomas
#4
Yara Backes, Sjoerd G Elias, John N Groen, Matthijs P Schwartz, Frank H J Wolfhagen, Joost M J Geesing, Frank Ter Borg, Jeroen van Bergeijk, Bernhard W M Spanier, Wouter H de Vos Tot Nederveen Cappel, Koen Kessels, Cornelis A Seldenrijk, Mihaela G Raicu, Paul Drillenburg, Anya N Milne, Marjon Kerkhof, Tom C J Seerden, Peter D Siersema, Frank P Vleggaar, G Johan A Offerhaus, Miangela M Lacle, Leon M G Moons
BACKGROUND & AIMS: Most patients with pedunculated T1 colorectal tumors referred for surgery are not found to have lymph node metastases, and were therefore unnecessarily placed at risk for surgery-associated complications. We aimed to identify factors associated with need for surgery in patients with pedunculated T1 colorectal tumors. METHODS: We performed a cohort-nested matched case-control study of 708 patients diagnosed with pedunculated T1 colorectal tumors at 13 hospitals in The Netherlands, from January 1, 2000 through December 31, 2014, followed for a median 44 months (interquartile range, 20-80 months)...
January 20, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29305934/efficacy-of-laparoscopic-nissen-fundoplication-vs-transoral-incisionless-fundoplication-or-proton-pump-inhibitors-in-patients-with-gastroesophageal-reflux-disease-a-systematic-review-and-network-meta-analysis
#5
Joel Richter, Ambuj Kumar, Seth Lipka, Branko Miladinovic, Vic Velanovich
BACKGROUND & AIMS: The effects of transoral incisionless fundoplication (TIF) and laparoscopic Nissen fundoplication (LNF) have been compared with those of proton pump inhibitors (PPIs) or a sham procedure in patients with gastroesophageal reflux disease (GERD), but there has been no direct comparison of TIF vs LNF. We performed a systematic review and network meta-analysis of randomized controlled trials to compare the relative efficacies of TIF vs LNF in patients with GERD. METHODS: We searched publication databases and conference abstracts through May 10, 2017 for randomized controlled trials that compared the efficacy of TIF or LNF with that of a sham procedure or PPIs in patients with GERD...
January 3, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29206812/when-and-how-to-stop-surveillance-colonoscopy-in-older-adults-five-rules-of-thumb-for-practitioners
#6
Jennifer K Maratt, Audrey H Calderwood, Sameer D Saini
No abstract text is available yet for this article.
January 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29178033/a-review-of-neuropathic-pain-from-guidelines-to-clinical-practice
#7
REVIEW
Giorgio Cruccu, Andrea Truini
Neuropathic pain is a chronic condition representing a significant burden for patients, society, and healthcare systems. The prevalence of neuropathic pain in the general population has been estimated at 7-8% and is expected to increase in the future. Neuropathic pain differs from nociceptive pain and requires a different therapeutic approach; and the management of neuropathic pain is complicated and challenging. This chapter discusses clinical practice guidelines for neuropathic pain and their usefulness in clinical practice...
December 2017: Pain and Therapy
https://www.readbyqxmd.com/read/29331946/management-of-patients-on-antithrombotic-agents-undergoing-emergency-and-elective-endoscopy-joint-asian-pacific-association-of-gastroenterology-apage-and-asian-pacific-society-for-digestive-endoscopy-apsde-practice-guidelines
#8
Francis K L Chan, Khean-Lee Goh, Nageshwar Reddy, Kazuma Fujimoto, Khek Yu Ho, Seiji Hokimoto, Young-Hoon Jeong, Takanari Kitazono, Hong Sik Lee, Varocha Mahachai, Kelvin K F Tsoi, Ming-Shiang Wu, Bryan P Yan, Kentaro Sugano
This Guideline is a joint official statement of the Asian Pacific Association of Gastroenterology (APAGE) and the Asian Pacific Society for Digestive Endoscopy (APSDE). It was developed in response to the increasing use of antithrombotic agents (antiplatelet agents and anticoagulants) in patients undergoing gastrointestinal (GI) endoscopy in Asia. After reviewing current practice guidelines in Europe and the USA, the joint committee identified unmet needs, noticed inconsistencies, raised doubts about certain recommendations and recognised significant discrepancies in clinical practice between different regions...
March 2018: Gut
https://www.readbyqxmd.com/read/28766210/positive-ultrasound-guided-lymph-node-needle-biopsy-in-breast-cancer-may-not-mandate-axillary-lymph-node-dissection
#9
Christine K Harris, Hanh Tam Tran, Katherine Lee, Charles Mylander, Daina Pack, Martin Rosman, Lorraine Tafra, Christopher B Umbricht, Reema Andrade, Wen Liang, Rubie Sue Jackson
BACKGROUND: The ACOSOG Z0011 (Z11) trial demonstrated that in patients with nonpalpable axillary lymph nodes (LN) and one to two positive sentinel LN (SLN), axillary LN dissection (ALND) is unnecessary.JAMA 305:569-575, [2011], Ann Surg 264:413-42, [2016] The Z11 trial did not require preoperative axillary ultrasound (axUS). In many centers, preoperative axUS is part of the standard workup of a newly diagnosed breast cancer patient, but in light of the Z11 results, its role is now questioned...
October 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29322212/meta-analysis-on-materials-and-techniques-for-laparotomy-closure-the-match-review
#10
REVIEW
N A Henriksen, E B Deerenberg, L Venclauskas, R H Fortelny, M Miserez, F E Muysoms
BACKGROUND: The aim of this systematic review and meta-analysis was to evaluate closure materials and suture techniques for emergency and elective laparotomies. The primary outcome was incisional hernia after 12 months, and the secondary outcomes were burst abdomen and surgical site infection. METHODS: A systematic literature search was conducted until September 2017. The quality of the RCTs was evaluated by at least 3 assessors using critical appraisal checklists...
January 10, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29045062/tokyo-guidelines-2018-flowchart-for-the-management-of-acute-cholecystitis
#11
LETTER
Kohji Okamoto, Kenji Suzuki, Tadahiro Takada, Steven M Strasberg, Horacio J Asbun, Itaru Endo, Yukio Iwashita, Taizo Hibi, Henry A Pitt, Akiko Umezawa, Koji Asai, Ho-Seong Han, Tsann-Long Hwang, Yasuhisa Mori, Yoo-Seok Yoon, Wayne Shih-Wei Huang, Giulio Belli, Christos Dervenis, Masamichi Yokoe, Seiki Kiriyama, Takao Itoi, Palepu Jagannath, O James Garden, Fumihiko Miura, Masafumi Nakamura, Akihiko Horiguchi, Go Wakabayashi, Daniel Cherqui, Eduardo de Santibañes, Satoru Shikata, Yoshinori Noguchi, Tomohiko Ukai, Ryota Higuchi, Keita Wada, Goro Honda, Avinash Nivritti Supe, Masahiro Yoshida, Toshihiko Mayumi, Dirk J Gouma, Daniel J Deziel, Kui-Hin Liau, Miin-Fu Chen, Kazunori Shibao, Keng-Hao Liu, Cheng-Hsi Su, Angus C W Chan, Dong-Sup Yoon, In-Seok Choi, Eduard Jonas, Xiao-Ping Chen, Sheung Tat Fan, Chen-Guo Ker, Mariano Eduardo Giménez, Seigo Kitano, Masafumi Inomata, Koichi Hirata, Kazuo Inui, Yoshinobu Sumiyama, Masakazu Yamamoto
We propose a new flowchart for the treatment of acute cholecystitis (AC) in the Tokyo Guidelines 2018 (TG18). Grade III AC was not indicated for straightforward laparoscopic cholecystectomy (Lap-C). Following analysis of subsequent clinical investigations and drawing on Big Data in particular, TG18 proposes that some Grade III AC can be treated by Lap-C when performed at advanced centers with specialized surgeons experienced in this procedure and for patients that satisfy certain strict criteria. For Grade I, TG18 recommends early Lap-C if the patients meet the criteria of Charlson comorbidity index (CCI) ≤5 and American Society of Anesthesiologists physical status classification (ASA-PS) ≤2...
October 16, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28844205/ultrasound-guided-central-venous-catheter-placement-a-structured-review-and-recommendations-for-clinical-practice
#12
REVIEW
Bernd Saugel, Thomas W L Scheeren, Jean-Louis Teboul
The use of ultrasound (US) has been proposed to reduce the number of complications and to increase the safety and quality of central venous catheter (CVC) placement. In this review, we describe the rationale for the use of US during CVC placement, the basic principles of this technique, and the current evidence and existing guidelines for its use. In addition, we recommend a structured approach for US-guided central venous access for clinical practice. Static and real-time US can be used to visualize the anatomy and patency of the target vein in a short-axis and a long-axis view...
August 28, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28953552/lichtenstein-versus-total-extraperitoneal-patch-plasty-versus-transabdominal-patch-plasty-technique-for-primary-unilateral-inguinal-hernia-repair-a-registry-based-propensity-score-matched-comparison-of-57-906-patients
#13
Ferdinand Köckerling, Reinhard Bittner, Michael Kofler, Franz Mayer, Daniela Adolf, Andreas Kuthe, Dirk Weyhe
OBJECTIVE: Outcome comparison of the Lichtenstein, total extraperitoneal patch plasty (TEP), and transabdominal patch plasty (TAPP) techniques for primary unilateral inguinal hernia repair. BACKGROUND: For comparison of these techniques the number of cases included in meta-analyses of randomized controlled trials is limited. There is therefore an urgent need for more comparative data. METHODS: In total, 57,906 patients with a primary unilateral inguinal hernia and 1-year follow up from the Herniamed Registry were selected between September 1, 2009 and February 1, 2015...
September 26, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28943323/hartmann-s-procedure-or-primary-anastomosis-for-generalized-peritonitis-due-to-perforated-diverticulitis-a-prospective-multicenter-randomized-trial-diverti
#14
Valerie Bridoux, Jean Marc Regimbeau, Mehdi Ouaissi, Muriel Mathonnet, Francois Mauvais, Estelle Houivet, Lilian Schwarz, Diane Mege, Igor Sielezneff, Charles Sabbagh, Jean-Jacques Tuech
BACKGROUND: About 25% of patients with acute diverticulitis require emergency intervention. Currently, most patients with diverticular peritonitis undergo a Hartmann's procedure. Our objective was to assess whether primary anastomosis (PA) with a diverting stoma results in lower mortality rates than Hartmann's procedure (HP) in patients with diverticular peritonitis. STUDY DESIGN: We conducted a multicenter randomized controlled trial conducted between June 2008 and May 2012: the DIVERTI (Primary vs Secondary Anastomosis for Hinchey Stage III-IV Diverticulitis) trial...
September 22, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28916971/emergency-room-visits-and-readmissions-following-implementation-of-an-enhanced-recovery-after-surgery-ieras-program
#15
Trevor Wood, Mary-Anne Aarts, Allan Okrainec, Emily Pearsall, J Charles Victor, Marg McKenzie, Ori Rotstein, Robin S McLeod
BACKGROUND: Enhanced Recovery After Surgery (ERAS) guidelines have been widely promoted and supported largely due to several studies showing decreased post-operative complications and length of stay. The objective of this study was to review the emergency room (ER) visits and readmission rates and reasons for both in patients who were part of the Implementation of an Enhanced Recovery After Surgery (iERAS) program for colorectal surgery. METHODS: All patients having elective colorectal surgery at 15 academic hospitals were enrolled in the iERAS program...
February 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28898379/effect-of-axillary-dissection-vs-no-axillary-dissection-on-10-year-overall-survival-among-women-with-invasive-breast-cancer-and-sentinel-node-metastasis-the-acosog-z0011-alliance-randomized-clinical-trial
#16
RANDOMIZED CONTROLLED TRIAL
Armando E Giuliano, Karla V Ballman, Linda McCall, Peter D Beitsch, Meghan B Brennan, Pond R Kelemen, David W Ollila, Nora M Hansen, Pat W Whitworth, Peter W Blumencranz, A Marilyn Leitch, Sukamal Saha, Kelly K Hunt, Monica Morrow
Importance: The results of the American College of Surgeons Oncology Group Z0011 (ACOSOG Z0011) trial were first reported in 2005 with a median follow-up of 6.3 years. Longer follow-up was necessary because the majority of the patients had estrogen receptor-positive tumors that may recur later in the disease course (the ACOSOG is now part of the Alliance for Clinical Trials in Oncology). Objective: To determine whether the 10-year overall survival of patients with sentinel lymph node metastases treated with breast-conserving therapy and sentinel lymph node dissection (SLND) alone without axillary lymph node dissection (ALND) is noninferior to that of women treated with axillary dissection...
September 12, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28624127/surgical-personalities-surgical-burnout-and-surgical-happiness
#17
EDITORIAL
Samuel R Money
No abstract text is available yet for this article.
September 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28780717/proton-pump-inhibitors-in-gastroesophageal-reflux-disease-friend-or-foe
#18
REVIEW
C Prakash Gyawali
PURPOSE OF REVIEW: Proton pump inhibitor (PPI) use in gastroesophageal reflux disease (GERD) has been redefined, in light of recent advances highlighting GERD phenotypes that respond to PPIs, and fresh revelations of potential risks of long-term PPI therapy. RECENT FINDINGS: Erosive esophagitis predicts excellent response to PPI therapy, but non-erosive reflux disease (NERD) with abnormal reflux parameters on ambulatory reflux monitoring also demonstrates a similar response...
September 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28761572/a-case-of-severe-iron-deficiency-anemia-associated-with-long-term-proton-pump-inhibitor-use
#19
REVIEW
David N Dado, Erin B Loesch, Sudha P Jaganathan
The use of proton pump inhibitors (PPIs) in the treatment of gastrointestinal diseases has evolved over recent years. Initially intended for short-term use, PPIs are increasingly being used, often inappropriately, as long-term maintenance medications. The mechanism of action of PPIs is suppression of gastric basal and stimulated acid secretion by inhibiting the parietal cell H+/K+ ATP pump with a resultant increase in gastric pH and hypo- or achlorhydria. Although short-term use is related to few adverse effects, long-term use is associated with numerous complications...
2017: Current Therapeutic Research, Clinical and Experimental
https://www.readbyqxmd.com/read/20054046/chlorhexidine-alcohol-versus-povidone-iodine-for-surgical-site-antisepsis
#20
RANDOMIZED CONTROLLED TRIAL
Rabih O Darouiche, Matthew J Wall, Kamal M F Itani, Mary F Otterson, Alexandra L Webb, Matthew M Carrick, Harold J Miller, Samir S Awad, Cynthia T Crosby, Michael C Mosier, Atef Alsharif, David H Berger
BACKGROUND: Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis may decrease postoperative infections. We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine. METHODS: We randomly assigned adults undergoing clean-contaminated surgery in six hospitals to preoperative skin preparation with either chlorhexidine-alcohol scrub or povidone-iodine scrub and paint...
January 7, 2010: New England Journal of Medicine
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