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Acné

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22 papers 0 to 25 followers nathan
https://www.readbyqxmd.com/read/29194776/endosymbiosis-and-its-significance-in-dermatology
#1
REVIEW
K Kubiak, H Sielawa, W Chen, E Dzika
Proposed at the beginning of the twentieth century to explain the origin of eukaryotic organelles from prokaryotes, endosymbiosis is now medically defined by various interaction patterns between microorganisms and their residing hosts, best exemplified by the bacterial endosymbiont Wolbachia identified in arthropods and filarial nematodes, which can influence normal development, reproduction, survival and transmission of the hosts. Based on the transmission modes, vertical or horizontal, and the function of the endosymbionts, the host-symbiont dependence can be divided into primary or secondary...
March 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29226630/microneedling-combined-with-platelet-rich-plasma-or-trichloroacetic-acid-peeling-for-management-of-acne-scarring-a-split-face-clinical-and-histologic-comparison
#2
Moetaz El-Domyati, Hossam Abdel-Wahab, Aliaa Hossam
BACKGROUND: Minimally invasive procedures provide effective, safe, relatively long-lasting, and natural results without large damage to the skin. A combination treatment is considered an approach that includes at least 2 different and unrelated modalities. OBJECTIVES: This study aims to evaluate the use and effectiveness of some combined minimally invasive procedures for management of acne scarring. PATIENTS/METHODS: Twenty-four volunteers with postacne atrophic scars were randomly divided into 3 equal groups according to performed procedure on each side of the face (microneedling by dermaroller alone or combined with platelet-rich plasma [PRP] or trichloroacetic acid [TCA] 15% peeling) and received 6 bi-weekly sessions of treatment...
February 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29344322/acne-scarring-pathogenesis-evaluation-and-treatment-options
#3
REVIEW
Deirdre Connolly, Ha Linh Vu, Kavita Mariwalla, Nazanin Saedi
Acne vulgaris is a ubiquitous problem affecting 80 percent of people ages 11 to 30 years, with many patients experiencing some degree of scarring. This review focuses on atrophic scars, the most common type of acne scar. We briefly address the cellular sequelae that lead to scar formation and the initial evaluation of patients with acne scars. We then discuss an algorithmic approach to the treatment of acne scarring based on the classification of scars into erythematous and atrophic types. Lastly, we discuss the future treatment of acne scars and ongoing clinical trials...
September 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29377341/the-influence-of-exposome-on-acne
#4
Brigitte Dréno, Vincenzo Bettoli, Elena Araviiskaia, Miguel Sanchez Viera, Anne Bouloc
BACKGROUND: Acne vulgaris is one of the main reasons for dermatological consultations. Severity and response to treatment may be impacted by various external factors or exposome. AIM: to assess the impact of environmental factors on acne and to provide a comprehensive overview of the acne exposome. METHODS: two consensus meetings of five European dermatologists and a comprehensive literature search on exposome factors triggering acne served as a basis for this review...
January 29, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29440921/adult-onset-acne-prevalence-impact-and-management-challenges
#5
REVIEW
Marco A Rocha, Ediléia Bagatin
Acne is a multifactorial and inflammatory disease of pilosebaceous follicles, which affects most adolescents. Recent epidemiological data revealed a difference in adults affected by this disease. Women have a high prevalence and incidence when compared with men, especially after 25 years of age. In contrast to what was initially thought, most of these patients do not present endocrinopathy capable of leading to the development of the lesions. When present, polycystic ovarian syndrome is the main cause. However, in these cases, acne is rarely the only dermatological manifestation; hirsutism and acanthosis nigricans are often present...
2018: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28658462/isotretinoin-and-timing-of-procedural-interventions-a-systematic-review-with-consensus-recommendations
#6
REVIEW
Leah K Spring, Andrew C Krakowski, Murad Alam, Ashish Bhatia, Jeremy Brauer, Joel Cohen, James Q Del Rosso, Lucia Diaz, Jeffrey Dover, Lawrence F Eichenfield, Geoffrey C Gurtner, C William Hanke, Marla N Jahnke, Kristen M Kelly, Shilpi Khetarpal, Megan A Kinney, Moise L Levy, James Leyden, Michael T Longaker, Girish S Munavalli, David M Ozog, Heidi Prather, Peter R Shumaker, Elizabeth Tanzi, Abel Torres, Mara Weinstein Velez, Abigail B Waldman, Albert C Yan, Andrea L Zaenglein
Importance: The notion that systemic isotretinoin taken within 6 to 12 months of cutaneous surgery contributes to abnormal scarring or delayed wound healing is widely taught and practiced; however, it is based on 3 small case series from the mid-1980s. Objective: To evaluate the body of literature to provide evidence-based recommendations regarding the safety of procedural interventions performed either concurrently with, or immediately following the cessation of systemic isotretinoin therapy...
August 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28063095/the-use-of-cosmeceuticals-in-acne-help-or-hoax
#7
REVIEW
Brittany S Barros, Andrea L Zaenglein
The use of cosmeceuticals by patients with acne is common; however, their role is unclear and confusing, with many asking, "Do they really help acne?" Cosmeceuticals are intermediate products between prescription medications and cosmetics, available to consumers over the counter. These products are popular and may be used without the direct supervision of a dermatologist, creating a practice gap in educating patients. Herein, a variety of cosmeceuticals are discussed, including retinoids, niacinamide, and glycolic acid...
April 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/21491169/multimodal-management-of-atrophic-acne-scarring-in-the-aging-face
#8
REVIEW
T Gerald O'Daniel
Atrophic facial acne scarring is a widely prevalent condition that can have a negative impact on a patient's quality of life. The appearance of these scars is often worsened by the normal effects of aging. A number of options are available for the treatment of acne scarring, including chemical peeling, dermabrasion, ablative or nonablative laser resurfacing, dermal fillers, and surgical techniques such as subcision or punch excision. Depending on the type and extent of scarring, a multimodal approach is generally necessary to provide satisfactory results...
December 2011: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/27621661/hormonal-treatment-of-acne-vulgaris-an-update
#9
REVIEW
Mohamed L Elsaie
Acne vulgaris is a common skin condition associated with multiple factors. Although mostly presenting alone, it can likewise present with features of hyperandrogenism and hormonal discrepancies. Of note, hormonal therapies are indicated in severe, resistant-to-treatment cases and in those with monthly flare-ups and when standard therapeutic options are inappropriate. This article serves as an update to hormonal pathogenesis of acne, discusses the basics of endocrinal evaluation for patients with suspected hormonal acne, and provides an overview of the current hormonal treatment options in women...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/26491364/fillers-for-the-improvement-in-acne-scars
#10
REVIEW
Uwe Wollina, Alberto Goldman
Acne is a common inflammatory disease. Scarring is an unwanted end point of acne. Both atrophic and hypertrophic scar types occur. Soft-tissue augmentation aims to improve atrophic scars. In this review, we will focus on the use of dermal fillers for acne scar improvement. Therefore, various filler types are characterized, and available data on their use in acne scar improvement are analyzed.
2015: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/26203267/linking-diet-to-acne-metabolomics-inflammation-and-comedogenesis-an-update
#11
REVIEW
Bodo C Melnik
Acne vulgaris, an epidemic inflammatory skin disease of adolescence, is closely related to Western diet. Three major food classes that promote acne are: 1) hyperglycemic carbohydrates, 2) milk and dairy products, 3) saturated fats including trans-fats and deficient ω-3 polyunsaturated fatty acids (PUFAs). Diet-induced insulin/insulin-like growth factor (IGF-1)-signaling is superimposed on elevated IGF-1 levels during puberty, thereby unmasking the impact of aberrant nutrigenomics on sebaceous gland homeostasis...
2015: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/25255769/acne-in-vivo-morphologic-study-of-lesions-and-surrounding-skin-by-means-of-reflectance-confocal-microscopy
#12
M Manfredini, G Mazzaglia, S Ciardo, F Farnetani, V D Mandel, C Longo, S Zauli, V Bettoli, A Virgili, G Pellacani
BACKGROUND: Acne vulgaris is a common disease of the pilosebaceous unit, clinically showing alteration of the keratinization process leading to comedos formation and subsequent inflammatory process. OBJECTIVE: To characterize the morphology of acne lesions and pilosebaceous units by means of in vivo reflectance confocal microscopy, in order to non-invasively define the microscopic alterations occurring during the acne process. METHODS: A set of standardized clinical pictures and a set of reflectance confocal images were acquired from 25 volunteers, presenting mild-to-moderate acne, and 10 healthy volunteers, using Vivascope 3000, and 10 mosaics on apparently normal skin were acquired by 5 acne patients and 5 healthy volunteers by Vivascope 1500, and evaluated by experts...
May 2015: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/24880665/meta-analysis-comparing-efficacy-of-antibiotics-versus-oral-contraceptives-in-acne-vulgaris
#13
COMPARATIVE STUDY
Eubee Baughn Koo, Tyler Daniel Petersen, Alexandra Boer Kimball
BACKGROUND: Both antibiotics and oral contraceptive pills (OCPs) have been found to be effective in managing acne vulgaris. Despite widespread use, few direct comparisons of efficacy between the 2 modalities have been published. OBJECTIVE: We compared the efficacy of antibiotics and OCPs in managing acne. METHODS: A meta-analysis was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Cochrane collaboration guidelines...
September 2014: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/24641090/systematic-review-on-the-rapidity-of-the-onset-of-action-of-topical-treatments-in-the-therapy-of-mild-to-moderate-acne-vulgaris
#14
REVIEW
A Jacobs, G Starke, S Rosumeck, A Nast
The time until a patient achieves a relevant improvement during the treatment of a skin disease is important for selecting a therapy, but has been largely neglected in reviews and guidelines. The aim of this systematic review was to determine the time until the onset of action (TOA) of topical acne treatments. The primary outcome was the TOA defined as the time until a 25% reduction in the mean number of inflammatory lesions had been achieved. A systematic literature search in Medline and Embase was carried out...
March 2014: British Journal of Dermatology
https://www.readbyqxmd.com/read/24481999/medical-adherence-to-acne-therapy-a-systematic-review
#15
REVIEW
Stephanie Snyder, Ian Crandell, Scott A Davis, Steven R Feldman
BACKGROUND: Poor adherence of acne patients to treatment may equate to poor clinical efficacy, increased healthcare costs, and unnecessary treatments. Authors have investigated risk factors for poor medical adherence and how to improve this difficult problem in the context of acne. OBJECTIVE: This systematic review aims to describe what methods have been used to measure adherence, what is known about acne patients' adherence to treatment, and the factors affecting adherence...
April 2014: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/23657872/treatment-of-acne-vulgaris-during-pregnancy-and-lactation
#16
REVIEW
Y L Kong, H L Tey
Acne vulgaris is a common problem encountered by pregnant and lactating women. Unfortunately, in clinical practice, treatment is often not optimized as a result of the lack of safety data and unified recommendations on the use of the various anti-acne therapies. In this narrative review, current data on their safety is summarized. We recommend the use of topical medications as first-line treatment for acne vulgaris in pregnant and lactating women. These include antibiotics (erythromycin, clindamycin, metronidazole and dapsone), benzoyl peroxide, azelaic acid and salicylic acid...
June 2013: Drugs
https://www.readbyqxmd.com/read/23210645/epidemiology-of-acne-vulgaris
#17
REVIEW
K Bhate, H C Williams
Despite acne being an almost universal condition in younger people, relatively little is known about its epidemiology. We sought to review what is known about the distribution and causes of acne by conducting a systematic review of relevant epidemiological studies. We searched Medline and Embase to the end of November 2011. The role of Propionibacterium acnes in pathogenesis is unclear: antibiotics have a direct antimicrobial as well as an anti-inflammatory effect. Moderate-to-severe acne affects around 20% of young people and severity correlates with pubertal maturity...
March 2013: British Journal of Dermatology
https://www.readbyqxmd.com/read/22849351/management-of-acne-scarring-part-ii-a-comparative-review-of-non-laser-based-minimally-invasive-approaches
#18
REVIEW
Lauren L Levy, Joshua A Zeichner
Acne scarring is a commonly encountered yet extremely challenging problem to treat for the dermatologist. As acne scarring can lead to significant psychological distress and low self-esteem, it is of utmost importance to have effective and satisfying treatments in the physician's armamentarium. However, many treatments are unsatisfying, leading to patient disappointment and frustration. Although early treatment of acne lesions and inflammation with isotretinoin is beneficial in preventing acne scarring, many patients still present with troubling noticeable scars...
October 1, 2012: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/22612738/management-of-acne-scarring-part-i-a-comparative-review-of-laser-surgical-approaches
#19
REVIEW
Joseph F Sobanko, Tina S Alster
Acne scarring is the result of a deviation in the orderly pattern of healing and can have profound psychosocial implications for patients. While the most effective means of addressing acne scarring is to prevent its formation through good acne control, there are a number of therapeutic interventions that improve the appearance of acne scars. Many of these procedural modalities have flaws and are limited by operator skill and experience. Laser scar revision, on the other hand, is a precise, well tolerated procedure with clinically demonstrable efficacy and minimal adverse effects that may be used alone or in combination with other scar treatments...
October 1, 2012: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/22486762/guidance-on-the-diagnosis-and-clinical-management-of-acne
#20
REVIEW
C B Archer, S N Cohen, S E Baron
This article discusses the effects of acne (sometimes referred to as acne vulgaris), how to diagnose it confidently and how to distinguish it from rosacea, and the options available for treatment, especially in primary care. We also suggest when referral to dermatology should be considered, and try to anticipate some frequently asked questions.
May 2012: Clinical and Experimental Dermatology
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