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Acné

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26 papers 0 to 25 followers nathan
https://www.readbyqxmd.com/read/24313686/randomized-trial-of-three-phototherapy-methods-for-the-treatment-of-acne-vulgaris-in-chinese-patients
#1
RANDOMIZED CONTROLLED TRIAL
Li-Hong Liu, Xin Fan, Yu-Xi An, Jin Zhang, Cong-Min Wang, Rong-Ya Yang
BACKGROUND AND AIMS: Acne vulgaris is common in Asian populations. We compared three methods of phototherapy for the treatment of moderate to severe facial acne vulgaris in Chinese patients. METHODS: Patients were randomly assigned to receive photodynamic therapy (PDT), intense pulsed light (IPL) or blue-red light-emitting diode (LED) phototherapy to the right side of the face until the inflammatory lesion count reduced by ≥ 90%. Patients were examined at 1 and 3 months after the final treatment...
October 2014: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/22419445/diet-in-acne-further-evidence-for-the-role-of-nutrient-signalling-in-acne-pathogenesis
#2
COMMENT
Bodo C Melnik
Recent evidence underlines the role of Western diet in the pathogenesis of acne. Acne is absent in populations consuming Palaeolithic diets with low glycaemic load and no consumption of milk or dairy products. Two randomized controlled studies, one of which is presented in this issue of Acta Dermato-Venereologica, have provided evidence for the beneficial therapeutic effects of low glycaemic load diets in acne. Epidemiological evidence confirms that milk consumption has an acne-promoting or acne-aggravating effect...
May 2012: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29241749/acne-vulgaris-the-metabolic-syndrome-of-the-pilosebaceous-follicle
#3
Bodo C Melnik
Acne vulgaris is an epidemic inflammatory disease of the human sebaceous follicle and represents the most common skin disease affecting about 85% of adolescents in Westernized populations. Acne vulgaris is primarily a disease of wealthy countries and exhibits higher prevalence rates in developed compared with developing countries. No acne has been found in non-Westernized populations still living under Paleolithic dietary conditions constraining hyperglycemic carbohydrates, milk, and dairy products. The high prevalence rates of adolescent acne cannot be explained by the predominance of genetic factors but by the influence of a Western diet that overstimulates the key conductor of metabolism, the nutrient- and growth factor-sensitive kinase mTORC1...
January 2018: Clinics in Dermatology
https://www.readbyqxmd.com/read/25454036/diet-in-dermatology-part-i-atopic-dermatitis-acne-and-nonmelanoma-skin-cancer
#4
REVIEW
Tara Bronsnick, Era Caterina Murzaku, Babar K Rao
Patients commonly inquire about dietary modifications as a means to prevent or manage skin disease. Answering these questions is often challenging, given the vast and conflicting evidence that exists on this topic. This 2-part continuing medical education article summarizes the evidence to date to enable physicians to answer patients' questions in an evidence-based manner. Part I includes atopic dermatitis, acne, and nonmelanoma skin cancer. The role of dietary supplementation, dietary exclusion, food allergy, maternal diet, and breastfeeding in the development and/or prevention of atopic dermatitis is summarized...
December 2014: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29194776/endosymbiosis-and-its-significance-in-dermatology
#5
REVIEW
K Kubiak, H Sielawa, W Chen, E Dzika
Proposed at the beginning of the twentieth century to explain the origin of eukaryotic organelles from prokaryotes, endosymbiosis is now medically defined by various interaction patterns between microorganisms and their residing hosts, best exemplified by the bacterial endosymbiont Wolbachia identified in arthropods and filarial nematodes, which can influence normal development, reproduction, survival and transmission of the hosts. Based on the transmission modes, vertical or horizontal, and the function of the endosymbionts, the host-symbiont dependence can be divided into primary or secondary...
March 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29226630/microneedling-combined-with-platelet-rich-plasma-or-trichloroacetic-acid-peeling-for-management-of-acne-scarring-a-split-face-clinical-and-histologic-comparison
#6
Moetaz El-Domyati, Hossam Abdel-Wahab, Aliaa Hossam
BACKGROUND: Minimally invasive procedures provide effective, safe, relatively long-lasting, and natural results without large damage to the skin. A combination treatment is considered an approach that includes at least 2 different and unrelated modalities. OBJECTIVES: This study aims to evaluate the use and effectiveness of some combined minimally invasive procedures for management of acne scarring. PATIENTS/METHODS: Twenty-four volunteers with postacne atrophic scars were randomly divided into 3 equal groups according to performed procedure on each side of the face (microneedling by dermaroller alone or combined with platelet-rich plasma [PRP] or trichloroacetic acid [TCA] 15% peeling) and received 6 bi-weekly sessions of treatment...
February 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29344322/acne-scarring-pathogenesis-evaluation-and-treatment-options
#7
REVIEW
Deirdre Connolly, Ha Linh Vu, Kavita Mariwalla, Nazanin Saedi
Acne vulgaris is a ubiquitous problem affecting 80 percent of people ages 11 to 30 years, with many patients experiencing some degree of scarring. This review focuses on atrophic scars, the most common type of acne scar. We briefly address the cellular sequelae that lead to scar formation and the initial evaluation of patients with acne scars. We then discuss an algorithmic approach to the treatment of acne scarring based on the classification of scars into erythematous and atrophic types. Lastly, we discuss the future treatment of acne scars and ongoing clinical trials...
September 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29377341/the-influence-of-exposome-on-acne
#8
B Dréno, V Bettoli, E Araviiskaia, M Sanchez Viera, A Bouloc
BACKGROUND: Acne vulgaris is one of the main reasons for dermatological consultations. Severity and response to treatment may be impacted by various external factors or exposome. AIM: To assess the impact of environmental factors on acne and to provide a comprehensive overview of the acne exposome. METHODS: Two consensus meetings of five European dermatologists and a comprehensive literature search on exposome factors triggering acne served as a basis for this review...
May 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29440921/adult-onset-acne-prevalence-impact-and-management-challenges
#9
REVIEW
Marco A Rocha, Ediléia Bagatin
Acne is a multifactorial and inflammatory disease of pilosebaceous follicles, which affects most adolescents. Recent epidemiological data revealed a difference in adults affected by this disease. Women have a high prevalence and incidence when compared with men, especially after 25 years of age. In contrast to what was initially thought, most of these patients do not present endocrinopathy capable of leading to the development of the lesions. When present, polycystic ovarian syndrome is the main cause. However, in these cases, acne is rarely the only dermatological manifestation; hirsutism and acanthosis nigricans are often present...
2018: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28658462/isotretinoin-and-timing-of-procedural-interventions-a-systematic-review-with-consensus-recommendations
#10
REVIEW
Leah K Spring, Andrew C Krakowski, Murad Alam, Ashish Bhatia, Jeremy Brauer, Joel Cohen, James Q Del Rosso, Lucia Diaz, Jeffrey Dover, Lawrence F Eichenfield, Geoffrey C Gurtner, C William Hanke, Marla N Jahnke, Kristen M Kelly, Shilpi Khetarpal, Megan A Kinney, Moise L Levy, James Leyden, Michael T Longaker, Girish S Munavalli, David M Ozog, Heidi Prather, Peter R Shumaker, Elizabeth Tanzi, Abel Torres, Mara Weinstein Velez, Abigail B Waldman, Albert C Yan, Andrea L Zaenglein
Importance: The notion that systemic isotretinoin taken within 6 to 12 months of cutaneous surgery contributes to abnormal scarring or delayed wound healing is widely taught and practiced; however, it is based on 3 small case series from the mid-1980s. Objective: To evaluate the body of literature to provide evidence-based recommendations regarding the safety of procedural interventions performed either concurrently with, or immediately following the cessation of systemic isotretinoin therapy...
August 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28063095/the-use-of-cosmeceuticals-in-acne-help-or-hoax
#11
REVIEW
Brittany S Barros, Andrea L Zaenglein
The use of cosmeceuticals by patients with acne is common; however, their role is unclear and confusing, with many asking, "Do they really help acne?" Cosmeceuticals are intermediate products between prescription medications and cosmetics, available to consumers over the counter. These products are popular and may be used without the direct supervision of a dermatologist, creating a practice gap in educating patients. Herein, a variety of cosmeceuticals are discussed, including retinoids, niacinamide, and glycolic acid...
April 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/21491169/multimodal-management-of-atrophic-acne-scarring-in-the-aging-face
#12
REVIEW
T Gerald O'Daniel
Atrophic facial acne scarring is a widely prevalent condition that can have a negative impact on a patient's quality of life. The appearance of these scars is often worsened by the normal effects of aging. A number of options are available for the treatment of acne scarring, including chemical peeling, dermabrasion, ablative or nonablative laser resurfacing, dermal fillers, and surgical techniques such as subcision or punch excision. Depending on the type and extent of scarring, a multimodal approach is generally necessary to provide satisfactory results...
December 2011: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/27621661/hormonal-treatment-of-acne-vulgaris-an-update
#13
REVIEW
Mohamed L Elsaie
Acne vulgaris is a common skin condition associated with multiple factors. Although mostly presenting alone, it can likewise present with features of hyperandrogenism and hormonal discrepancies. Of note, hormonal therapies are indicated in severe, resistant-to-treatment cases and in those with monthly flare-ups and when standard therapeutic options are inappropriate. This article serves as an update to hormonal pathogenesis of acne, discusses the basics of endocrinal evaluation for patients with suspected hormonal acne, and provides an overview of the current hormonal treatment options in women...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/26491364/fillers-for-the-improvement-in-acne-scars
#14
REVIEW
Uwe Wollina, Alberto Goldman
Acne is a common inflammatory disease. Scarring is an unwanted end point of acne. Both atrophic and hypertrophic scar types occur. Soft-tissue augmentation aims to improve atrophic scars. In this review, we will focus on the use of dermal fillers for acne scar improvement. Therefore, various filler types are characterized, and available data on their use in acne scar improvement are analyzed.
2015: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/26203267/linking-diet-to-acne-metabolomics-inflammation-and-comedogenesis-an-update
#15
REVIEW
Bodo C Melnik
Acne vulgaris, an epidemic inflammatory skin disease of adolescence, is closely related to Western diet. Three major food classes that promote acne are: 1) hyperglycemic carbohydrates, 2) milk and dairy products, 3) saturated fats including trans-fats and deficient ω-3 polyunsaturated fatty acids (PUFAs). Diet-induced insulin/insulin-like growth factor (IGF-1)-signaling is superimposed on elevated IGF-1 levels during puberty, thereby unmasking the impact of aberrant nutrigenomics on sebaceous gland homeostasis...
2015: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/25255769/acne-in-vivo-morphologic-study-of-lesions-and-surrounding-skin-by-means-of-reflectance-confocal-microscopy
#16
M Manfredini, G Mazzaglia, S Ciardo, F Farnetani, V D Mandel, C Longo, S Zauli, V Bettoli, A Virgili, G Pellacani
BACKGROUND: Acne vulgaris is a common disease of the pilosebaceous unit, clinically showing alteration of the keratinization process leading to comedos formation and subsequent inflammatory process. OBJECTIVE: To characterize the morphology of acne lesions and pilosebaceous units by means of in vivo reflectance confocal microscopy, in order to non-invasively define the microscopic alterations occurring during the acne process. METHODS: A set of standardized clinical pictures and a set of reflectance confocal images were acquired from 25 volunteers, presenting mild-to-moderate acne, and 10 healthy volunteers, using Vivascope 3000, and 10 mosaics on apparently normal skin were acquired by 5 acne patients and 5 healthy volunteers by Vivascope 1500, and evaluated by experts...
May 2015: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/24880665/meta-analysis-comparing-efficacy-of-antibiotics-versus-oral-contraceptives-in-acne-vulgaris
#17
COMPARATIVE STUDY
Eubee Baughn Koo, Tyler Daniel Petersen, Alexandra Boer Kimball
BACKGROUND: Both antibiotics and oral contraceptive pills (OCPs) have been found to be effective in managing acne vulgaris. Despite widespread use, few direct comparisons of efficacy between the 2 modalities have been published. OBJECTIVE: We compared the efficacy of antibiotics and OCPs in managing acne. METHODS: A meta-analysis was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Cochrane collaboration guidelines...
September 2014: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/24641090/systematic-review-on-the-rapidity-of-the-onset-of-action-of-topical-treatments-in-the-therapy-of-mild-to-moderate-acne-vulgaris
#18
REVIEW
A Jacobs, G Starke, S Rosumeck, A Nast
The time until a patient achieves a relevant improvement during the treatment of a skin disease is important for selecting a therapy, but has been largely neglected in reviews and guidelines. The aim of this systematic review was to determine the time until the onset of action (TOA) of topical acne treatments. The primary outcome was the TOA defined as the time until a 25% reduction in the mean number of inflammatory lesions had been achieved. A systematic literature search in Medline and Embase was carried out...
March 2014: British Journal of Dermatology
https://www.readbyqxmd.com/read/24481999/medical-adherence-to-acne-therapy-a-systematic-review
#19
REVIEW
Stephanie Snyder, Ian Crandell, Scott A Davis, Steven R Feldman
BACKGROUND: Poor adherence of acne patients to treatment may equate to poor clinical efficacy, increased healthcare costs, and unnecessary treatments. Authors have investigated risk factors for poor medical adherence and how to improve this difficult problem in the context of acne. OBJECTIVE: This systematic review aims to describe what methods have been used to measure adherence, what is known about acne patients' adherence to treatment, and the factors affecting adherence...
April 2014: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/23657872/treatment-of-acne-vulgaris-during-pregnancy-and-lactation
#20
REVIEW
Y L Kong, H L Tey
Acne vulgaris is a common problem encountered by pregnant and lactating women. Unfortunately, in clinical practice, treatment is often not optimized as a result of the lack of safety data and unified recommendations on the use of the various anti-acne therapies. In this narrative review, current data on their safety is summarized. We recommend the use of topical medications as first-line treatment for acne vulgaris in pregnant and lactating women. These include antibiotics (erythromycin, clindamycin, metronidazole and dapsone), benzoyl peroxide, azelaic acid and salicylic acid...
June 2013: Drugs
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