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Outstanding Clinical Review

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631 papers 100 to 500 followers
By Mohammed Liaquatullah Imtiaz Endocrinologist
https://www.readbyqxmd.com/read/29776516/tactical-emergency-medicine-support
#1
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
June 2018: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29769136/vitamin-d-and-juvenile-idiopathic-arthritis
#2
REVIEW
Sarah L Finch, Alan M Rosenberg, Hassan Vatanparast
BACKGROUND: Vitamin D has been implicated in the pathogenesis of autoimmune diseases. While the roles of vitamin D in other autoimmune diseases have been investigated, less is known about the role of vitamin D in chronic childhood arthritis. MAIN BODY: This review summarizes and evaluates evidence relating to 25-hydroxyvitamin D (25(OH)D) and chronic childhood arthritis. A scoping literature review was conducted using Ovid Medline, Ovid Embase, Cumulative Index to Nursing and Allied Health Literature, Web of Science and Scopus...
May 16, 2018: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/25569020/the-role-of-tonsillectomy-in-the-treatment-of-pediatric-autoimmune-neuropsychiatric-disorders-associated-with-streptococcal-infections-pandas
#3
Daniel Demesh, Jordan M Virbalas, John P Bent
IMPORTANCE: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) in children describes neuropsychiatric symptom exacerbations that relate temporally to streptococcal infections. Recent case reports suggest tonsillectomy may effectively reduce these symptoms; however, no consensus treatment guidelines exist. This study examines whether tonsillectomy improves neuropsychiatric symptoms in children with PANDAS who have incomplete response to antibiotic therapy...
March 2015: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29735778/clinical-reasoning-accumulating-endocrinopathies-in-a-car-salesman
#4
Luuk Wieske, Ulrich Beuers, Matthijs C Brouwer
No abstract text is available yet for this article.
May 8, 2018: Neurology
https://www.readbyqxmd.com/read/29730088/aspiration-pneumonia-and-related-syndromes
#5
REVIEW
Augustine S Lee, Jay H Ryu
Aspiration is a syndrome with variable respiratory manifestations that span acute, life-threatening illnesses, such as acute respiratory distress syndrome, to chronic, sometimes insidious, respiratory disorders such as aspiration bronchiolitis. Diagnostic testing is limited by the insensitivity of histologic testing, and although gastric biomarkers for aspiration are increasingly available, none have been clinically validated. The leading mechanism for microaspiration is thought to be gastroesophageal reflux disease, largely driven by the increased prevalence of gastroesophageal reflux across a variety of respiratory disorders, including chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis, and chronic cough...
May 2, 2018: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29477208/rivaroxaban-in-peripheral-artery-disease-the-new-kid-on-the-block
#6
EDITORIAL
Mohamad A Hussain, Subodh Verma, Mohammed Al-Omran
No abstract text is available yet for this article.
March 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29720964/preoperative-molecular-markers-in-thyroid-nodules
#7
REVIEW
Zeyad T Sahli, Philip W Smith, Christopher B Umbricht, Martha A Zeiger
The need for distinguishing benign from malignant thyroid nodules has led to the pursuit of differentiating molecular markers. The most common molecular tests in clinical use are Afirma® Gene Expression Classifier (GEC) and Thyroseq® V2. Despite the rapidly developing field of molecular markers, several limitations exist. These challenges include the recent introduction of the histopathological diagnosis "Non-Invasive Follicular Thyroid neoplasm with Papillary-like nuclear features", the correlation of genetic mutations within both benign and malignant pathologic diagnoses, the lack of follow-up of molecular marker negative nodules, and the cost-effectiveness of molecular markers...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29726951/walnut-consumption-alters-the-gastrointestinal-microbiota-microbially-derived-secondary-bile-acids-and-health-markers-in-healthy-adults-a-randomized-controlled-trial
#8
Hannah D Holscher, Heather M Guetterman, Kelly S Swanson, Ruopeng An, Nirupa R Matthan, Alice H Lichtenstein, Janet A Novotny, David J Baer
Background: Epidemiologic data suggest that diets rich in nuts have beneficial health effects, including reducing total and cause-specific mortality from cancer and heart disease. Although there is accumulating preclinical evidence that walnuts beneficially affect the gastrointestinal microbiota and gut and metabolic health, these relations have not been investigated in humans. Objective: We aimed to assess the impact of walnut consumption on the human gastrointestinal microbiota and metabolic markers of health...
May 3, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29724357/arrhythmias-in-patients-%C3%A2-80-years-of-age-pathophysiology-management-and-outcomes
#9
REVIEW
Anne B Curtis, Roshan Karki, Alexander Hattoum, Umesh C Sharma
Advances in medical care have led to an increase in the number of octogenarians and even older patients, forming an important and unique patient subgroup. It is clear that advancing age is an independent risk factor for the development of most arrhythmias, causing substantial morbidity and mortality. Patients ≥80 years of age have significant structural and electrical remodeling of cardiac tissue; accrue competing comorbidities; react differently to drug therapy; and may experience falls, frailty, and cognitive impairment, presenting significant therapeutic challenges...
May 8, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29751980/preserve-the-end-or-the-beginning-of-a-new-era-in-prevention-of-contrast-associated-acute-kidney-injury
#10
EDITORIAL
Richard Solomon
No abstract text is available yet for this article.
May 8, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29540496/exacerbations-of-copd
#11
Christian Viniol, Claus F Vogelmeier
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer from exacerbations. Severe exacerbations are related to a significantly worse survival outcome. This review summarises the current knowledge on the different aspects of COPD exacerbations. The impact of risk factors and triggers such as smoking, severe airflow limitation, bronchiectasis, bacterial and viral infections and comorbidities is discussed...
March 31, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/29502716/recent-advances-in-the-acute-management-of-intracerebral-hemorrhage
#12
REVIEW
Joseph D Burns, Jennifer L Fisher, Anna M Cervantes-Arslanian
Primary intracerebral hemorrhage (ICH) is a common, devastating disease that lacks an effective specific treatment. Mortality is high, functional outcomes are poor, and these have not substantially changed for decades. There is, therefore, considerable opportunity for advancement in the management of ICH. In recent years, a significant amount of research has begun to address this gap. This article is aimed at updating neurologists on the most clinically relevant contemporary research.
April 2018: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/29707074/hepatobiliary-manifestations-and-complications-in-inflammatory-bowel-disease-a-review
#13
REVIEW
Fotios S Fousekis, Vasileios I Theopistos, Konstantinos H Katsanos, Epameinondas V Tsianos, Dimitrios K Christodoulou
Liver and biliary track diseases are common extraintestinal manifestations of inflammatory bowel disease (IBD), reported both in Crohn's disease and ulcerative colitis, and may occur at any time during the natural course of the disease. Their etiology is mainly related to pathophysiological changes induced by IBD, and secondary, due to drugs used in IBD. Fatty liver is considered as the most frequent hepatobiliary manifestation in IBD, while primary sclerosing cholangitis (PSC) is the most correlated hepatobiliary disorder and is more prevalent in patients with ulcerative colitis...
April 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29500312/etiology-and-pharmacology-of-neuropathic-pain
#14
REVIEW
Sascha R A Alles, Peter A Smith
Injury to or disease of the nervous system can invoke chronic and sometimes intractable neuropathic pain. Many parallel, interdependent, and time-dependent processes, including neuroimmune interactions at the peripheral, supraspinal, and spinal levels, contribute to the etiology of this "disease of pain." Recent work emphasizes the roles of colony-stimulating factor 1, ATP, and brain-derived neurotrophic factor. Excitatory processes are enhanced, and inhibitory processes are attenuated in the spinal dorsal horn and throughout the somatosensory system...
April 2018: Pharmacological Reviews
https://www.readbyqxmd.com/read/29746673/frank-s-sign-in-ischemic-stroke
#15
Liliana R Santos, Patrícia Martins, Teresa Melo, Ana P Vilas
No abstract text is available yet for this article.
May 8, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29746657/imaging-features-of-sarcoidosis
#16
Joanna G Escalon, David A Lynch
No abstract text is available yet for this article.
May 8, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29616422/ajcc-8th-edition-colorectal-cancer
#17
EDITORIAL
Martin R Weiser
No abstract text is available yet for this article.
June 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29683196/hypogonadism-and-male-obesity-focus-on-unresolved-questions
#18
Mathis Grossmann
Obesity, increasing in prevalence globally, is the clinical condition most strongly associated with lowered testosterone concentrations in men, and presents as one of the strongest predictors of receiving testosterone treatment. While low circulating total testosterone concentrations in modest obesity primarily reflect reduced concentrations of sex hormone binding globulin, more marked obesity can lead to genuine hypothalamic-pituitary-testicular axis (HPT) suppression. HPT axis suppression is likely mediated via pro-inflammatory cytokine and dysregulated leptin signalling and aggravated by associated comorbidities...
April 23, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29770124/does-family-history-of-obesity-cardiovascular-and-metabolic-diseases-influence-onset-and-severity-of-childhood-obesity
#19
Domenico Corica, Tommaso Aversa, Mariella Valenzise, Maria Francesca Messina, Angela Alibrandi, Filippo De Luca, Malgorzata Wasniewska
Objectives: The objectives were to evaluate (1) the metabolic profile and cardiometabolic risk in overweight/obese children at first assessment, stratifying patients according to severity of overweight and age; and (2) to investigate the relationship between family history (FH) for obesity and cardiometabolic diseases and severity of childhood obesity. Methods: In this cross-sectional, retrospective, observational study, 260 children (139 female), aged between 2...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29525034/common-procedures-common-problems-it-s-complicated
#20
EDITORIAL
Mark D Miller
No abstract text is available yet for this article.
April 2018: Clinics in Sports Medicine
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