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Neonatal Nutrition

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208 papers 25 to 100 followers
https://www.readbyqxmd.com/read/29731360/hyperglycemia-in-extremely-preterm-infants-insulin-treatment-mortality-and-nutrient-intakes
#1
Itay Zamir, Andreas Tornevi, Thomas Abrahamsson, Fredrik Ahlsson, Eva Engström, Boubou Hallberg, Ingrid Hansen-Pupp, Elisabeth Stoltz Sjöström, Magnus Domellöf
OBJECTIVE: To explore the prevalence of hyperglycemia and the associations between nutritional intakes, hyperglycemia, insulin treatment, and mortality in extremely preterm infants. STUDY DESIGN: Prospectively collected data from the Extremely Preterm Infants in Sweden Study (EXPRESS) was used in this study and included 580 infants born <27 gestational weeks during 2004-2007. Available glucose measurements (n = 9850) as well as insulin treatment and nutritional data were obtained retrospectively from hospital records for the first 28 postnatal days as well as 28- and 70-day mortality data...
May 3, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29710251/growth-and-growth-charts-in-children
#2
Lindsay A Thompson, Megan A Moreno
No abstract text is available yet for this article.
April 30, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29691880/early-postnatal-growth-and-neurodevelopment-in-children-born-moderately-preterm-or-small-for-gestational-age-at-term-a-systematic-review
#3
REVIEW
Marion Taine, Marie-Aline Charles, Jacques Beltrand, Jean Christophe Rozé, Juliane Léger, Jérémie Botton, Barbara Heude
BACKGROUND: Clinicians' interest in the long-term effects of early postnatal growth (EPG) is growing. There is compelling evidence linking rapid EPG with later cardiovascular risk, but its neurodevelopmental benefits still remain hypothetical in individuals born moderately preterm (MP) or small for gestational at term (SGAT). METHODS: The objective was to perform a systematic review of the relationship between EPG before age 3 years and neurodevelopmental outcome for individuals born MP (32-36 weeks' gestational age) or SGAT...
April 25, 2018: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/29679047/a-quality-improvement-initiative-to-reduce-necrotizing-enterocolitis-across-hospital-systems
#4
Amy T Nathan, Laura Ward, Kurt Schibler, Laurel Moyer, Andrew South, Heather C Kaplan
OBJECTIVE: Necrotizing enterocolitis (NEC) is a devastating intestinal disease in premature infants. Local rates of NEC were unacceptably high. We hypothesized that utilizing quality improvement methodology to standardize care and apply evidence-based practices would reduce our rate of NEC. STUDY DESIGN: A multidisciplinary team used the model for improvement to prioritize interventions. Three neonatal intensive care units (NICUs) developed a standardized feeding protocol for very low birth weight (VLBW) infants, and employed strategies to increase the use of human milk, maximize intestinal perfusion, and promote a healthy microbiome...
April 20, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29688458/preterm-infants-have-distinct-microbiomes-not-explained-by-mode-of-delivery-breastfeeding-duration-or-antibiotic-exposure
#5
Cecilie Dahl, Hein Stigum, Jørgen Valeur, Nina Iszatt, Virissa Lenters, Shyamal Peddada, Jørgen V Bjørnholt, Tore Midtvedt, Siddhartha Mandal, Merete Eggesbø
Background: Preterm infants have low gut microbial diversity and few anaerobes. It is unclear whether the low diversity pertains to prematurity itself or is due to differences in delivery mode, feeding mode or exposure to antibiotics. Methods: The Norwegian Microbiota Study (NoMIC) was established to examine the colonization of the infant gut and health outcomes. 16S rRNA gene Illumina amplicon-sequenced samples from 519 children (160 preterms), collected at 10 days, 4 months and 1 year postnatally, were used to calculate alpha diversity...
April 20, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29572221/are-we-giving-too-much-iv-fluid
#6
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29571821/care-of-the-growth-restricted-newborn
#7
REVIEW
Bianca Carducci, Zulfiqar A Bhutta
With the first 1,000 days of life proving to be a critical window of opportunity for physical and cognitive growth and development, an optimal intrauterine environment is vital. If fetus needs are compromised prenatally, there is an increased risk of intrauterine growth restriction (IUGR), and infants being born premature, low birth weight (LBW), or small-for-gestational age (SGA). Specialized care of these high-risk infants is necessary in terms of preconception interventions, resuscitation, thermoregulation, nutritional support and kangaroo mother care...
February 26, 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29603403/comparison-of-calorie-and-protein-intake-of-very-low-birth-weight-infants-receiving-mother-s-own-milk-or-donor-milk-when-the-nutrient-composition-of-human-milk-is-measured-with-a-breast-milk-analyzer
#8
Melanie Newkirk, Fauzia Shakeel, Prabhu Parimi, Pamela Rothpletz-Puglia, Rachael Patusco, Andrea Fleisch Marcus, Rebecca Brody
BACKGROUND: In premature infants, donor breast milk (DBM) is assumed to provide reduced nutrients vs. mother's own milk (MOM). This study examined calorie and protein delivery when very low birth weight infants were fed fortified MOM or DBM, with a known nutrient composition, relative to established nutrition recommendations and to determine if there were differences between the groups. METHODS: A retrospective medical record review was conducted in 29 very low birth weight infants receiving MOM or DBM...
March 30, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29618272/does-fortification-of-pasteurized-donor-human-milk-increase-the-incidence-of-necrotizing-enterocolitis-among-preterm-neonates-a-randomized-controlled-trial
#9
Bethou Adhisivam, Dilesh Kohat, Vasanthan Tanigasalam, Vishnu Bhat, Nishad Plakkal, C Palanivel
OBJECTIVE: To compare the effect of fortified pasteurized donor human milk (PDHM) versus unfortified PDHM on the incidence of necrotizing enterocolitis (NEC) and immediate outcome among preterm neonates. METHODS: This randomized controlled trial (RCT) conducted in a tertiary care teaching hospital, south India included 80 healthy preterm neonates randomized to two groups (Group A and B). Neonates in Group A and B were fed with fortified PDHM and unfortified PDHM respectively...
April 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29603412/improving-nutrition-outcomes-for-infants-1500-grams-with-a-progressive-evidenced-based-enteral-feeding-protocol
#10
Melissa K Thoene, Elizabeth Lyden, Ann Anderson-Berry
BACKGROUND: Growth is essential for very low birth weight infants. The purpose of this retrospective chart review was to evaluate the impact of a new standardized, evidenced-based feeding protocol for infants born < 1500 g in correlation with growth and clinical outcomes. METHODS: Growth and nutrition data was reviewed from 2 groups of infants born < 1500 g within a level III newborn intensive care unit (NICU). Epoch 1 infants (N = 32) received care following initial implementation of a standardized enteral feeding protocol...
March 30, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29470322/pediatric-gastroesophageal-reflux-clinical-practice-guidelines-joint-recommendations-of-the-north-american-society-for-pediatric-gastroenterology-hepatology-and-nutrition-and-the-european-society-for-pediatric-gastroenterology-hepatology-and-nutrition
#11
Rachel Rosen, Yvan Vandenplas, Maartje Singendonk, Michael Cabana, Carlo DiLorenzo, Frederic Gottrand, Sandeep Gupta, Miranda Langendam, Annamaria Staiano, Nikhil Thapar, Neelesh Tipnis, Merit Tabbers
This document serves as an update of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) 2009 clinical guidelines for the diagnosis and management of gastroesophageal reflux disease (GERD) in infants and children and is intended to be applied in daily practice and as a basis for clinical trials. Eight clinical questions addressing diagnostic, therapeutic and prognostic topics were formulated...
March 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29402455/routine-supplementation-of-lactobacillus-rhamnosus-gg-and-risk-of-necrotizing-enterocolitis-in-very-low-birth-weight-infants
#12
Andrea F Kane, Anisha D Bhatia, Patricia W Denning, Andi L Shane, Ravi Mangal Patel
OBJECTIVE: To evaluate if routine supplementation of Lactobacillus rhamnosus GG ATCC 53103 (LGG) is associated with a decreased risk of necrotizing enterocolitis in very low birth weight (VLBW) infants. STUDY DESIGN: Retrospective observational cohort study of VLBW (<1500 g) infants at a single center from 2008 to 2016. LGG supplementation with Culturelle at a dose of 2.5 to 5 × 109 CFU/day began in 2014. We used multivariable logistic regression to evaluate the association between LGG supplementation and necrotizing enterocolitis (modified Bell stage IIA or greater), after adjusting for potential confounders...
April 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29407004/breast-milk-is-conditionally-perfect
#13
Miriam Erick
Breast milk is the universal preferred nutrition for the newborn human infant. New mother have been encouraged to exclusively breastfeed by health care professionals and consumer-advocacy forums for years, citing "breast milk is the perfect food". The benefits are numerous and include psychological, convenience, economical, ecological and nutritionally superior. Human milk is a composite of nutritional choices of the mother, commencing in the pre-conceptual era. Events influencing the eventual nutritional profile of breast milk for the neonate start with pre-conceptual dietary habits through pregnancy and finally to postpartum...
February 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29543698/dose-response-relationship-between-donor-human-milk-mother-s-own-milk-preterm-formula-and-neonatal-growth-outcomes
#14
Elizabeth A Brownell, Adam P Matson, Kelsey C Smith, James E Moore, Patricia A Esposito, Mary M Lussier, Trudy J Lerer, James I Hagadorn
BACKGROUND: A dose-response relationship between proportions of donor human milk (DHM) intake and in-neonatal intensive care unit (in-NICU) growth rates, if any, remains poorly defined. Objective was to evaluate interrelationships between percentages of DHM, mother's own milk (MOM), and preterm formula (PF) intake and neonatal growth parameters at 36 weeks postmenstrual age or NICU discharge. METHODS: Infants eligible for this single-center retrospective study were inborn at ≤32 weeks gestation or ≤1800 g, stayed in the NICU for ≥7 days, and received enteral nutrition consisting of human milk fortified with Enfamil human milk fortifier acidified liquid...
March 14, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29462356/nutrient-fortification-of-human-donor-milk-affects-intestinal-function-and-protein-metabolism-in-preterm-pigs
#15
Jing Sun, Yanqi Li, Duc Ninh Nguyen, Martin S Mortensen, Chris H P van den Akker, Tom Skeath, Susanne E Pors, Stanislava Pankratova, Silvia Rudloff, Søren J Sørensen, Douglas G Burrin, Thomas Thymann, Per T Sangild
Background: Nutrient fortification of human milk is often required to secure adequate growth and organ development for very preterm infants. There is concern that formula-based fortifiers (FFs) induce intestinal dysfunction, feeding intolerance, and necrotizing enterocolitis (NEC). Bovine colostrum (BC) may be an alternative nutrient fortifier, considering its high content of protein and milk bioactive factors. Objective: We investigated whether BC was superior to an FF product based on processed bovine milk and vegetable oil to fortify donor human milk (DHM) for preterm pigs, used as a model for infants...
March 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29529139/protein-use-and-weight-gain-quality-in-very-low-birth-weight-preterm-infants-fed-human-milk-or-formula
#16
Laura Morlacchi, Paola Roggero, Maria Lorella Giannì, Beatrice Bracco, Debora Porri, Enrico Battiato, Camilla Menis, Nadia Liotto, Domenica Mallardi, Fabio Mosca
Background: Nutritional management of preterm infants aims to approximate the tissue growth and body composition of a fetus of the same postmenstrual age. The adequacy of the quality of protein supply can influence the rate and the relative quality of weight gain. Objective: We investigated the protein balance according to feeding regimen and the association between human milk feeding and fat-free mass content at the term-corrected age in very-low-birth-weight preterm infants...
February 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29276423/hypoglycemia-when-to-treat
#17
REVIEW
Venkat Reddy Kallem, Aakash Pandita, Girish Gupta
Hypoglycemia is the most common metabolic disorder encountered in neonates. The definition of hypoglycemia as well as its clinical significance and management remain controversial. Most cases of neonatal hypoglycemia are transient, respond readily to treatment, and are associated with an excellent prognosis. Persistent hypoglycemia is more likely to be associated with abnormal endocrine conditions, such as hyperinsulinemia, as well as possible neurologic sequelae. Manifestations of hypoglycemia include seizures which can result in noteworthy neuromorbidity in the long haul...
2017: Clinical Medicine Insights. Pediatrics
https://www.readbyqxmd.com/read/29579758/glucose-gel-in-infants-at-risk-for-transitional-neonatal-hypoglycemia
#18
Kartikeya Makker, Rana Alissa, Christopher Dudek, Laura Travers, Carmen Smotherman, Mark L Hudak
OBJECTIVE:  To evaluate whether glucose gel as a supplement to feedings in infants admitted to the newborn nursery at risk for neonatal hypoglycemia (NH) reduces the frequency of transfer to a higher level of care for intravenous dextrose treatment. STUDY DESIGN:  We revised our newborn nursery protocol for management of infants at risk for NH to include use of 40% glucose gel (200 mg/kg). Study population included late preterm, small and large for gestational age infants, and infants of diabetic mothers...
March 26, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29275816/probiotics-and-necrotizing-enterocolitis
#19
Ravi Mangal Patel, Mark A Underwood
In this review, we summarize existing knowledge regarding the effects of probiotics on necrotizing enterocolitis (NEC). We review the role of the microbiome in NEC and pre-clinical data on mechanisms of probiotic action. Next, we summarize existing randomized controlled trials and observational studies of probiotics to prevent NEC. We also summarize findings from several recent meta-analyses and report a new cumulative meta-analysis of probiotic trials. Finally, we review data from cohorts routinely using commercially available probiotics...
February 2018: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/29246130/enteral-vitamin-a-for-reducing-severity-of-bronchopulmonary-dysplasia-in-extremely-preterm-infants-a-randomised-controlled-trial
#20
Abhijeet Rakshasbhuvankar, Sanjay Patole, Karen Simmer, J Jane Pillow
BACKGROUND: Intramuscular vitamin A supplementation decreases the risk of bronchopulmonary dysplasia (BPD) in very-low-birth-weight preterm infants without significant adverse effects. However, intramuscular vitamin A supplementation is not widely accepted because of the discomfort and risk of trauma associated with repeated injections. Enteral vitamin A supplementation has not been studied adequately in the clinical trials. Enterally administered water-soluble vitamin A is absorbed better than the fat-soluble form...
December 16, 2017: BMC Pediatrics
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