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igg4

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5 papers 0 to 25 followers
https://www.readbyqxmd.com/read/27886799/igg4-related-disease-advances-in-the-diagnosis-and-treatment
#1
REVIEW
Pilar Brito-Zerón, Xavier Bosch, Manuel Ramos-Casals, John H Stone
IgG4-related disease is a rare immune-mediated systemic disease with the capability of involving essentially any organ. Although the presenting clinical features vary substantially according to the speciality to which patients present first, perhaps the most common clinical presentation is that of single or multiple organ enlargement, arousing suspicion of cancer. The disease is frequently diagnosed unexpectedly in pathological specimens or on imaging studies. The diagnostic approach is complex and includes not only IgG4-related tests (serum levels, circulating plasmablasts, and specific immunohistochemical studies), but also clinical, laboratory, and imaging tests as well as the typical histopathological features (lymphocytic infiltration, storiform fibrosis, eosinophilic infiltration, and obliterative phlebitis)...
April 2016: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/27790959/igg4-related-syndrome-another-multiorgan-disease-in-the-interest-field-of-internal-medicine
#2
Antonino Tuttolomondo, Irene Simonetta, Domenico Di Raimondo, Tiziana Di Chiara, Roberta Conigliaro, Francesca Corpora, Valerio Vassallo, Antonio Pinto
BACKGROUND: IgG4-related disease is a rare, clinical and pathologic disease entity of unknown etiology. Its main features are increased serum concentrations of IgG4 > 1,35 g/l, lymphocyte and IgG4+plasma-cell infiltration within tissues, fibrosis or sclerosis. The classical presentation of IgG4-RSD is pancreatitis which is combined with the involvement of biliary ducts in 74 percent of patients. Extrapancreatic manifestations include: abdominal or mediastinal lymphadenopathy; the involvement of salivary glands and lacrimal glands, kidneys, lung, retroperitoneum...
2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27325130/an-overview-of-the-diagnosis-and-management-of-immunoglobulin-g4-related-disease
#3
REVIEW
Debashis Haldar, Paul Cockwell, Alex G Richter, Keith J Roberts, Gideon M Hirschfield
No abstract text is available yet for this article.
September 20, 2016: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/26990055/igg4-related-disease-retrospective-analysis-of-one-hundred-sixty-six-patients
#4
Hiroshi Sekiguchi, Ryohei Horie, Mio Kanai, Reina Suzuki, Eunhee S Yi, Jay H Ryu
OBJECTIVE: To investigate clinical and pathologic aspects of IgG4-related disease (IgG4-RD) in non-Asian populations. METHODS: We conducted a retrospective review of the medical records of patients with IgG4-RD who presented to an academic medical center from January 1994 to September 2012. RESULTS: Among 166 patients identified, the median age at diagnosis was 61 years (interquartile range [IQR] 49-70 years), 75% were male, and 80% were white...
September 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/26112170/the-changing-faces-of-igg4-related-disease-clinical-manifestations-and-pathogenesis
#5
REVIEW
Arshia Duza Islam, Carlo Selmi, Ananya Datta-Mitra, Rebecca Sonu, Mingyi Chen, M Eric Gershwin, Siba P Raychaudhuri
Since the earliest reports in 2001, immunoglobulin G4 (IgG4)-related disease has been defined as an autoimmune systemic disease characterized by the lymphoplasmacytic infiltration of affected tissues leading to fibrosis and obliterative phlebitis along with elevated serum IgG4 levels. Prior to this unifying hypothesis, a plethora of clinical manifestations were considered as separate entities despite the similar laboratory profile. The pathology can be observed in virtually all organs and may thus be a challenging diagnosis, especially when the adequate clinical suspicion is not present or when obtaining a tissue biopsy is not feasible...
October 2015: Autoimmunity Reviews
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