Olca Basturk, Seung-Mo Hong, Laura D Wood, N Volkan Adsay, Jorge Albores-Saavedra, Andrew V Biankin, Lodewijk A A Brosens, Noriyoshi Fukushima, Michael Goggins, Ralph H Hruban, Yo Kato, David S Klimstra, Günter Klöppel, Alyssa Krasinskas, Daniel S Longnecker, Hanno Matthaei, G Johan A Offerhaus, Michio Shimizu, Kyoichi Takaori, Benoit Terris, Shinichi Yachida, Irene Esposito, Toru Furukawa
International experts met to discuss recent advances and to revise the 2004 recommendations for assessing and reporting precursor lesions to invasive carcinomas of the pancreas, including pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), mucinous cystic neoplasm, and other lesions. Consensus recommendations include the following: (1) To improve concordance and to align with practical consequences, a 2-tiered system (low vs. high grade) is proposed for all precursor lesions, with the provision that the current PanIN-2 and neoplasms with intermediate-grade dysplasia now be categorized as low grade...
December 2015: American Journal of Surgical Pathology