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MMCBreast Collection

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279 papers 100 to 500 followers
https://www.readbyqxmd.com/read/28822332/eso-esmo-3rd-international-consensus-guidelines-for-breast-cancer-in-young-women-bcy3
#1
Shani Paluch-Shimon, Olivia Pagani, Ann H Partridge, Omalkhair Abulkhair, Maria-João Cardoso, Rebecca Alexandra Dent, Karen Gelmon, Oreste Gentilini, Nadia Harbeck, Anita Margulies, Dror Meirow, Giancarlo Pruneri, Elzbieta Senkus, Tanja Spanic, Medha Sutliff, Luzia Travado, Fedro Peccatori, Fatima Cardoso
The 3rd International Consensus Conference for Breast Cancer in Young Women (BCY3) took place in November 2016, in Lugano, Switzerland organized by the European School of Oncology (ESO) and the European Society of Medical Oncologists (ESMO). Consensus recommendations for the management of breast cancer in young women were updated from BCY2 with incorporation of new evidence to inform the guidelines, and areas of research priorities were identified. This manuscript summarizes the ESO-ESMO international consensus recommendations, which are also endorsed by the European Society of Breast Specialists (EUSOMA)...
August 16, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28576177/updates-in-the-treatment-of-breast-cancer-with-radiotherapy
#2
REVIEW
Serguei A Castaneda, Jon Strasser
Breast-conserving therapy is one of the most remarkable achievements of modern cancer care. The authors review the evidence supporting the role of adjuvant radiotherapy as the standard of care for breast cancer after breast-conserving surgery, consensus guidelines for margins in invasive cancer disease and ductal carcinoma in situ, the role of partial-breast irradiation and hypofractionated whole-breast irradiation, and the evolving indications for postmastectomy radiation therapy and extent of nodal coverage...
July 2017: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/28797766/pregnancy-outcomes-after-a-breast-cancer-diagnosis-a-systematic-review-and-meta-analysis
#3
REVIEW
Brigitte Gerstl, Elizabeth Sullivan, Angela Ives, Christobel Saunders, Handan Wand, Antoinette Anazodo
Improvements in local and systemic treatment, along with earlier diagnoses through breast awareness and screening, have led to increases in survival and a decline in breast cancer (BC) recurrence. To the best of our knowledge, no meta-analysis has yet focused on pregnancy outcomes after BC treatment. Hence, our research group explored the reproductive outcomes (pregnancy, miscarriage, termination of pregnancy, live births) after BC treatment. The Embase, MEDLINE, PubMed, and Scopus databases were searched. Studies were included that reported on pregnancy and reproductive outcomes after treatment of BC...
July 10, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28797338/is-axillary-lymph-node-dissection-necessary-after-a-positive-sentinel-lymph-node-biopsy
#4
REVIEW
Lerna C Ozcan, Armando E Giuliano
No abstract text is available yet for this article.
September 2017: Advances in Surgery
https://www.readbyqxmd.com/read/28797032/comprehensive-geriatric-assessment-in-326-older-women-with-early-breast-cancer
#5
D O Okonji, R Sinha, I Phillips, D Fatz, A Ring
BACKGROUND: One-third of new early breast cancer diagnoses occur in women over 70 years old. However, older women are less likely to receive radical curative treatments. This study prospectively evaluated a cohort of older women using a Comprehensive Geriatric Assessment (CGA) to determine whether fitness explained the apparent under-treatment in this patient group. METHODS: In this multi-centre prospective study, patients aged ⩾70 years with Stages I-III breast cancer underwent a pretreatment baseline CGA consisting of eight assessment tools...
August 10, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28785186/ago-recommendations-for-the-diagnosis-and-treatment-of-patients-with-early-breast-cancer-update-2017
#6
Cornelia Liedtke, Marc Thill, Christian Jackisch, Christoph Thomssen, Volkmar Müller, Wolfgang Janni, Wolfgang Janni
No abstract text is available yet for this article.
July 2017: Breast Care
https://www.readbyqxmd.com/read/28766218/considerations-for-clinicians-in-the-diagnosis-prevention-and-treatment-of-breast-cancer-related-lymphedema-recommendations-from-an-expert-panel-part-2-preventive-and-therapeutic-options
#7
Sarah A McLaughlin, Sarah M DeSnyder, Suzanne Klimberg, Michael Alatriste, Francesco Boccardo, Mark L Smith, Alicia C Staley, Paul T R Thiruchelvam, Nancy A Hutchison, Jane Mendez, Fiona MacNeill, Frank Vicini, Stanley G Rockson, Sheldon M Feldman
No abstract text is available yet for this article.
August 1, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28766232/considerations-for-clinicians-in-the-diagnosis-prevention-and-treatment-of-breast-cancer-related-lymphedema-recommendations-from-a-multidisciplinary-expert-asbrs-panel-part-1-definitions-assessments-education-and-future-directions
#8
Sarah A McLaughlin, Alicia C Staley, Frank Vicini, Paul Thiruchelvam, Nancy A Hutchison, Jane Mendez, Fiona MacNeill, Stanley G Rockson, Sarah M DeSnyder, Suzanne Klimberg, Michael Alatriste, Francesco Boccardo, Mark L Smith, Sheldon M Feldman
No abstract text is available yet for this article.
August 1, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28762113/implications-of-breast-implant-associated-anaplastic-large-cell-lymphoma-bia-alcl-for-breast-cancer-reconstruction-an-update-for-surgical-oncologists
#9
Anne C O'Neill, Toni Zhong, Stefan O P Hofer
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare disease that has been diagnosed in an extremely small proportion of women with breast implants. The pathogenesis of this disease is currently poorly understood, but it appears to be related to textured implants. Recent high-profile media coverage of this rare clinical entity is likely to cause considerable anxiety for breast cancer patients who have undergone alloplastic breast reconstruction. The purpose of this review is to provide surgical oncologists with an evidence-based overview of the incidence, diagnosis, and management of BIA-ALCL with a particular emphasis on breast reconstruction cases...
July 31, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28728962/oncologic-safety-of-nipple-sparing-mastectomy-in-women-with-breast-cancer
#10
Barbara L Smith, Rong Tang, Upahvan Rai, Jennifer K Plichta, Amy S Colwell, Michele A Gadd, Michelle C Specht, William G Austen, Suzanne B Coopey
BACKGROUND: Nipple-sparing mastectomy (NSM) has gained popularity for breast cancer treatment and prevention. There are limited data about long-term oncologic safety of this procedure. STUDY DESIGN: We reviewed oncologic outcomes of consecutive therapeutic NSM at a single institution. Nipple-sparing mastectomy was offered to patients with no radiologic or clinical evidence of nipple involvement. RESULTS: There were 2,182 NSM performed from 2007 to 2016...
July 17, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28743035/current-trials-to-reduce-surgical-intervention-in-ductal-carcinoma-in-situ-of-the-breast-critical-review
#11
REVIEW
M Toss, I Miligy, A M Thompson, H Khout, A R Green, I O Ellis, E A Rakha
The high proportion of ductal carcinoma in situ (DCIS) presented in mammographic screening and the relatively low risk of progression to invasive disease have raised questions related to overtreatment. Following a review of current DCIS management protocols a more conservative approach has been suggested. Clinical trials have been introduced to evaluate the option of avoiding surgical intervention in a proportion of patients with DCIS defined as "low-risk" using certain clinicopathological criteria. These trials can potentially provide evidence-based models of active surveillance (with or without endocrine therapy) as a future management approach...
July 22, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28748445/surgeon-and-radiation-oncologist-views-on-omission-of-adjuvant-radiotherapy-for-older-women-with-early-stage-breast-cancer
#12
Dean A Shumway, Kent A Griffith, Michael S Sabel, Rochelle D Jones, Julie M Forstner, Terri L Bott-Kothari, Sarah T Hawley, Jacqueline Jeruss, Reshma Jagsi
PURPOSE: Although clinical trials have shown no survival advantage and only a modest improvement in local control from adjuvant radiotherapy after lumpectomy in older women with stage I, estrogen receptor-positive (ER+) breast cancer, radiotherapy is commonly administered, raising concerns about overtreatment. Therefore, we sought to evaluate physician views on omission of radiotherapy in older women with favorable prognosis breast cancer. METHODS: We surveyed a national sample of 713 radiation oncologists and 879 surgeons...
July 26, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28736057/regional-variation-in-breast-cancer-surgery-results-from-the-national-cancer-database-ncdb
#13
Alexander S Chiu, Princess Thomas, Brigid K Killelea, Nina Horowitz, Anees B Chagpar, Donald R Lannin
BACKGROUND: Early studies have shown significant regional differences in the utilization of breast-conserving therapy (BCT) and mastectomy with reconstruction. It is expected that with the passage of time and the adoption of national treatment guidelines, these disparities would disappear. METHODS: Patients with non-metastatic breast cancer who underwent surgery between 2004 and 2013 were analyzed using the National Cancer Database (NCDB). Trends in BCT and reconstruction were evaluated and multivariate logistic regression performed...
July 18, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28724125/comparison-of-wound-complications-after-immediate-delayed-and-secondary-breast-reconstruction-procedures
#14
Margaret A Olsen, Katelin B Nickel, Ida K Fox, Julie A Margenthaler, Anna E Wallace, Victoria J Fraser
Importance: Few data are available concerning surgical site infection (SSI) and noninfectious wound complications (NIWCs) after delayed (DR) and secondary reconstruction (SR) compared with immediate reconstruction (IR) procedures in the breast. Objective: To compare the incidence of SSI and NIWCs after implant and autologous IR, DR, and SR breast procedures after mastectomy. Design, Setting, and Participants: This retrospective cohort study included women aged 18 to 64 years undergoing mastectomy from January 1, 2004, through December 31, 2011...
July 19, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28719836/long-term-management-of-patients-with-hormone-receptor-positive-metastatic-breast-cancer-concepts-for-sequential-and-combination-endocrine-based-therapies
#15
REVIEW
Adam M Brufsky
Treatment options for hormone receptor-positive (HR-positive) metastatic breast cancer (MBC) continue to increase in parallel with expanding knowledge about the complex biology of breast cancer subtypes and resistance mechanisms to endocrine therapy. For patients with HR-positive MBC, there are now an unprecedented number of endocrine-based treatment options that can improve long-term outcomes, while preserving or optimizing quality of life, and that can be used before selecting more cytotoxic chemotherapeutic regimens...
July 6, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28732325/epidemiology-and-pathophysiology-of-pregnancy-associated-breast-cancer-a-review
#16
REVIEW
Rossana Ruiz, Carmen Herrero, Kathrin Strasser-Weippl, Diego Touya, Jessica St Louis, Alexandra Bukowski, Paul E Goss
The interactions between pregnancy and breast cancer (BC) are complex. Overall, parity is associated with long-term protective effects against BC, however in a small group of susceptible patients, pregnancy can lead to the development of a form of BC with a particularly poor prognosis. Pregnancy-associated breast cancer (PABC) remains an under-studied but important and growing clinical problem worldwide. Several aspects of PABC, including risk factors and mechanisms involved in its occurrence and aggressiveness, are incompletely understood...
July 18, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28726077/bioscore-a-staging-system-for-breast-cancer-patients-that-reflects-the-prognostic-significance-of-underlying-tumor-biology
#17
Elizabeth A Mittendorf, Mariana Chavez-MacGregor, Jose Vila, Min Yi, Daphne Y Lichtensztajn, Christina A Clarke, Sharon H Giordano, Kelly K Hunt
BACKGROUND: Biologic factors guide treatment decisions and have a significant impact on prognosis for breast cancer patients. This study was undertaken to develop a staging system incorporating biologic factors in addition to standard anatomic factors in the American Joint Committee on Cancer (AJCC) pathologic stage (PS) to assess disease-specific survival (DSS). METHODS: Overall, 3327 patients treated with surgery as an initial intervention at MD Anderson Cancer Center from 2007 to 2013 were identified...
July 19, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28712671/analysis-of-stereotactic-biopsies-performed-on-suspicious-calcifications-identified-within-24-months-after-completion-of-breast-conserving-surgery-and-radiation-therapy-for-early-breast-cancer-can-biopsy-be-obviated
#18
Rosalind P Candelaria, Palita Hansakul, Alastair M Thompson, Huong Le-Petross, Vicente Valero, Roland Bassett, Monica L Huang, Lumarie Santiago, Beatriz E Adrada
BACKGROUND: To determine the cancer yield of stereotactic biopsy of suspicious calcifications identified within 24 months after breast conservation therapy (BCT). METHODS: Retrospective review of stereotactic biopsies performed during 2009-2013 for suspicious calcifications in the ipsilateral breast of patients who completed BCT. RESULTS: 94/2773 (3.4%) had stereotactic biopsies for suspicious calcifications in the ipsilateral breast; 7/94 (7...
July 1, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28702894/21-gene-recurrence-score-and-locoregional-recurrence-in-lymph-node-negative-estrogen-receptor-positive-breast-cancer
#19
Gulisa Turashvili, Joanne F Chou, Edi Brogi, Monica Morrow, Maura Dickler, Larry Norton, Clifford Hudis, Hannah Y Wen
BACKGROUND/PURPOSE: The 21-gene recurrence score (RS) assay evaluates the likelihood of distant recurrence and benefit of chemotherapy in lymph node-negative, estrogen receptor (ER)-positive, HER2-negative breast cancer patients. The RS categories are associated with the risk of locoregional recurrence (LRR) in some, but not all studies. METHODS: We reviewed the institutional database to identify consecutive female patients with node-negative, ER+/HER2- breast carcinoma tested for the 21-gene RS assay and treated at our center from 2008 to 2013...
July 12, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28704697/the-use-of-ultrasound-in-the-clinical-re-staging-of-the-axilla-after-neoadjuvant-chemotherapy-nact
#20
Anastasia Peppe, Robin Wilson, Romney Pope, Kate Downey, Jennifer Rusby
INTRODUCTION: Ultrasound (US) is the imaging modality of choice for staging the axilla prior to surgery in patients with breast cancer (BC). High pathological complete response rates in the axilla after NACT mean a more conservative approach to surgery can be considered. Radiological re-staging is important in this decision making. After the presentation of results from ACOSOG Z1071 in December 2012, formal ultrasound re-assessment of the axilla after primary therapy was specifically requested in our institution...
July 10, 2017: Breast: Official Journal of the European Society of Mastology
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