collection
https://read.qxmd.com/read/27053638/early-administration-of-epinephrine-adrenaline-in-patients-with-cardiac-arrest-with-initial-shockable-rhythm-in-hospital-propensity-score-matched-analysis
#21
MULTICENTER STUDY
Lars W Andersen, Tobias Kurth, Maureen Chase, Katherine M Berg, Michael N Cocchi, Clifton Callaway, Michael W Donnino
OBJECTIVES: To evaluate whether patients who experience cardiac arrest in hospital receive epinephrine (adrenaline) within the two minutes after the first defibrillation (contrary to American Heart Association guidelines) and to evaluate the association between early administration of epinephrine and outcomes in this population. DESIGN: Prospective observational cohort study. SETTING: Analysis of data from the Get With The Guidelines-Resuscitation registry, which includes data from more than 300 hospitals in the United States...
April 6, 2016: BMJ: British Medical Journal
https://read.qxmd.com/read/27117874/a-randomized-controlled-noninferiority-trial-of-single-dose-of%C3%A2-oral-dexamethasone-versus-5-days-of-oral-prednisone-in-acute%C3%A2-adult-asthma
#22
RANDOMIZED CONTROLLED TRIAL
Matthew W Rehrer, Bella Liu, Marcela Rodriguez, Joseph Lam, Harrison J Alter
STUDY OBJECTIVE: Oral dexamethasone demonstrates bioavailability similar to that of oral prednisone but has a longer half-life. We evaluate whether a single dose of oral dexamethasone plus 4 days of placebo is not inferior to 5 days of oral prednisone in treatment of adults with mild to moderate asthma exacerbations to prevent relapse defined as an unscheduled return visit for additional treatment for persistent or worsening asthma within 14 days. METHODS: Adult emergency department patients (aged 18 to 55 years) were randomized to receive either a single dose of 12 mg of oral dexamethasone with 4 days of placebo or a 5-day course of oral prednisone 60 mg a day...
November 2016: Annals of Emergency Medicine
https://read.qxmd.com/read/26934549/evidence-based-medicine-has-been-hijacked-a-report-to-david-sackett
#23
JOURNAL ARTICLE
John P A Ioannidis
This is a confession building on a conversation with David Sackett in 2004 when I shared with him some personal adventures in evidence-based medicine (EBM), the movement that he had spearheaded. The narrative is expanded with what ensued in the subsequent 12 years. EBM has become far more recognized and adopted in many places, but not everywhere, for example, it never acquired much influence in the USA. As EBM became more influential, it was also hijacked to serve agendas different from what it originally aimed for...
May 2016: Journal of Clinical Epidemiology
https://read.qxmd.com/read/27021128/succinylcholine-in-an-ed-patient-with-unanticipated-hyperkalemia
#24
JOURNAL ARTICLE
Gabrielle Jacknin, Michael C Overbeck
No abstract text is available yet for this article.
October 2016: American Journal of Emergency Medicine
https://read.qxmd.com/read/27019140/challenging-the-culture-of-culturing-the-case-for-less-testing-and-more-clinical-assessment
#25
JOURNAL ARTICLE
Heidi L Wald
No abstract text is available yet for this article.
May 1, 2016: JAMA Internal Medicine
https://read.qxmd.com/read/26964827/the-effect-of-nebulized-magnesium-sulfate-in-the-treatment-of-moderate-to-severe-asthma-attacks-a-randomized-clinical-trial
#26
RANDOMIZED CONTROLLED TRIAL
Shaker Hossein, Akhavan Pegah, Farsi Davood, Abbasi Said, Mahshidfar Babak, Mofidi Mani, Rezai Mahdi, Hafezimoghadam Peyman
OBJECTIVE: Thirty percent of people with asthma do not respond to standard treatment, and complementary therapies are needed. The objective of this study was to investigate the impact of inhaled magnesium sulfate on the treatment response in emergency department (ED) patients with moderate to severe attacks of asthma. METHODS: This study is a randomized controlled trial, enrolling patients with moderate to severe asthma in the ED. Subjects allocated to the study group were treated with the standard, plus 3 ml of 260 mmol/L solution of magnesium sulfate every 20 to 60 minutes...
May 2016: American Journal of Emergency Medicine
https://read.qxmd.com/read/26893401/strategies-for-implementing-implementation-science-a-methodological-overview
#27
REVIEW
Margaret A Handley, Anuradha Gorukanti, Adithya Cattamanchi
A key reason for the consistent gaps between evidence and practice across all areas of medicine is that there has been little attempt to identify or target factors critical for successful implementation of an evidence-based intervention. There is either no explicit implementation strategy or the strategy is based on a best guess rather than on a systematic assessment of crucial barriers and enablers. A different approach is needed to close the evidence-practice gap and thereby achieve the triple aim of improved health, improved patient experience and reduced healthcare costs...
September 2016: Emergency Medicine Journal: EMJ
https://read.qxmd.com/read/26879765/transient-ischemic-attack-management-in-the-emergency-department-and-impact-of-an-outpatient-neurovascular-clinic
#28
COMPARATIVE STUDY
Gregory W Hosier, Stephen J Phillips, Steve P Doucette, Kirk D Magee, Gordon J Gubitz
OBJECTIVES: 1) To evaluate whether transient ischemic attack (TIA) management in emergency departments (EDs) of the Nova Scotia Capital District Health Authority followed Canadian Best Practice Recommendations, and 2) to assess the impact of being followed up in a dedicated outpatient neurovascular clinic. METHODS: Retrospective chart review of all patients discharged from EDs in our district from January 1, 2011 to December 31, 2012 with a diagnosis of TIA. Cox proportional hazards models, Kaplan-Meier survival curve, and propensity matched analyses were used to evaluate 90-day mortality and readmission...
September 2016: CJEM
https://read.qxmd.com/read/26855339/jinx-or-not-there-is-nothing-like-a-black-cloud-syndrome
#29
JOURNAL ARTICLE
Alexandre Fabre, Julien Mancini
OBJECTIVE: The aim of this study was to ascertain the validity of the widespread belief in the existence of jinxed physicians during night duty in emergency department (ED). METHODS: We conducted a retrospective study involving 13 pediatricians with more than 12 spells of night duty (8 PM to 8.30 AM) in the ED at the "La Timone" Medical School Hospital in Marseilles, France, during the inclusion period (from November 1, 2010, to October 31, 2011) and 8 night nurses in the same ED...
October 2017: Pediatric Emergency Care
https://read.qxmd.com/read/26836712/first-pass-success-without-hypoxemia-is-increased-with-the-use-of-apneic-oxygenation-during-rapid-sequence-intubation-in-the-emergency-department
#30
JOURNAL ARTICLE
John C Sakles, Jarrod M Mosier, Asad E Patanwala, Brittany Arcaris, John M Dicken
OBJECTIVES: The objective was to determine the effect of apneic oxygenation (AP OX) on first pass success without hypoxemia (FPS-H) in adult patients undergoing rapid sequence intubation (RSI) in the emergency department (ED). METHODS: Continuous quality improvement data were prospectively collected on all patients intubated in an academic ED from July 1, 2013, to June 30, 2015. During this period the use of AP OX was introduced and encouraged for all patients undergoing RSI in the ED...
June 2016: Academic Emergency Medicine
https://read.qxmd.com/read/26850577/does-reducing-inpatient-length-of-stay-have-upstream-effects-on-the-emergency-room-exploring-the-impact-of-the-general-internal-medicine-care-transformation-initiative
#31
JOURNAL ARTICLE
Finlay A McAlister, Jeffrey A Bakal, Rhonda J Rosychuk, Brian H Rowe
OBJECTIVE: The General Internal Medicine (GIM) Care Transformation Initiative implemented at one of four teaching hospitals in the same city resulted in improved efficiency of in-hospital care. Whether it had beneficial effects upstream in the emergency department (ED) is unclear. METHODS: Controlled before-after study of ED length of stay (LOS) and crowding metrics for the intervention site (n = 108,951 visits) compared to the three other teaching hospitals (controls, n = 300,930 visits)...
June 2016: Academic Emergency Medicine
https://read.qxmd.com/read/26843102/rivaroxaban-can-we-trust-the-evidence
#32
JOURNAL ARTICLE
Deborah Cohen
No abstract text is available yet for this article.
February 3, 2016: BMJ: British Medical Journal
https://read.qxmd.com/read/26803702/the-price-of-waiting-what-can-a-province-buy-for-109-million
#33
EDITORIAL
Jeremiah D Schuur, Arjun K Venkatesh
No abstract text is available yet for this article.
April 2016: Annals of Emergency Medicine
https://read.qxmd.com/read/26813674/6-pack-programme-to-decrease-fall-injuries-in-acute-hospitals-cluster-randomised-controlled-trial
#34
RANDOMIZED CONTROLLED TRIAL
Anna L Barker, Renata T Morello, Rory Wolfe, Caroline A Brand, Terry P Haines, Keith D Hill, Sandra G Brauer, Mari Botti, Robert G Cumming, Patricia M Livingston, Catherine Sherrington, Silva Zavarsek, Richard I Lindley, Jeannette Kamar
OBJECTIVE: To evaluate the effect of the 6-PACK programme on falls and fall injuries in acute wards. DESIGN: Cluster randomised controlled trial. SETTING: Six Australian hospitals. PARTICIPANTS: All patients admitted to 24 acute wards during the trial period. INTERVENTIONS: Participating wards were randomly assigned to receive either the nurse led 6-PACK programme or usual care over 12 months. The 6-PACK programme included a fall risk tool and individualised use of one or more of six interventions: "falls alert" sign, supervision of patients in the bathroom, ensuring patients' walking aids are within reach, a toileting regimen, use of a low-low bed, and use of a bed/chair alarm...
January 26, 2016: BMJ: British Medical Journal
https://read.qxmd.com/read/26806175/thrombotic-complications-following-the-administration-of-high-dose-prothrombin-complex-concentrate-for-acute-warfarin-reversal
#35
JOURNAL ARTICLE
Wesley R Zemrak, Erin Kelley, Nicole L Kovacic, Deirdre M Mooney, Jane G Morris, Casey Z MacVane, Jeffrey A Rosenblatt
No abstract text is available yet for this article.
August 2016: American Journal of Emergency Medicine
https://read.qxmd.com/read/26766429/generalizability-and-effectiveness-of-butterfly-phlebotomy-in-reducing-hemolysis
#36
JOURNAL ARTICLE
Douglas P Barnaby, Andrew Wollowitz, Deborah White, Scott Pearlman, Michelle Davitt, Laura Holihan, Polly Bijur, E John Gallagher
OBJECTIVES: The objective was to test the hypothesis that exclusive use of butterfly needles for phlebotomy, compared with sample collection via intravenous (IV) catheter, will reduce rates of sample hemolysis. METHODS: This was an observational study of hemolysis rates before and after implementation of a "butterfly-only" phlebotomy protocol. Weekly hemolysis rates, generated by the central laboratory, were collected and the proportion of hemolyzed specimens before and after protocol implementation were compared...
February 2016: Academic Emergency Medicine
https://read.qxmd.com/read/26720855/effect-of-randomized-clinical-trial-findings-on-emergency-management
#37
JOURNAL ARTICLE
Joel D Hudgins, Andrew M Fine, Florence T Bourgeois
OBJECTIVES: Research findings are not consistently adopted in the clinical setting and there is a gap between best evidence and clinical practice across a range of conditions and settings. A number of factors may contribute to this discrepancy, including the direction of the research findings (i.e., whether positive or negative for an intervention). The objectives of this study were to measure the translation of results from randomized controlled trials (RCTs) into clinical care and to determine whether the direction of the trial findings influence the uptake of research reports into clinical practice...
January 2016: Academic Emergency Medicine
https://read.qxmd.com/read/26658830/a-tincture-of-time-latent-crystal-formation-and-clinical-decision-making-in-acute-gout-a-teachable-moment
#38
JOURNAL ARTICLE
Juan N Lessing, Patrick C Mathias, Read G Pierce
No abstract text is available yet for this article.
February 2016: JAMA Internal Medicine
https://read.qxmd.com/read/26585046/can-you-multitask-evidence-and-limitations-of-task-switching-and-multitasking-in-emergency-medicine
#39
REVIEW
L Melissa Skaugset, Susan Farrell, Michele Carney, Margaret Wolff, Sally A Santen, Marcia Perry, Stephen John Cico
Emergency physicians work in a fast-paced environment that is characterized by frequent interruptions and the expectation that they will perform multiple tasks efficiently and without error while maintaining oversight of the entire emergency department. However, there is a lack of definition and understanding of the behaviors that constitute effective task switching and multitasking, as well as how to improve these skills. This article reviews the literature on task switching and multitasking in a variety of disciplines-including cognitive science, human factors engineering, business, and medicine-to define and describe the successful performance of task switching and multitasking in emergency medicine...
August 2016: Annals of Emergency Medicine
https://read.qxmd.com/read/26584627/comparison-of-tamsulosin-nifedipine-and-placebo-for-ureteric-colic
#40
COMPARATIVE STUDY
Michael Gottlieb, Damali Nakitende
Clinical question Do calcium channel blockers or alpha blockers improve renal stone passage when compared with placebo? Article chosen Pickard R, Starr K, MacLennan G, et al. Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial. Lancet 2015;386(9991):25-31, doi: 10.1016/S0140-6736(15)60933-3.
March 2017: CJEM
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