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Photobiomodulation

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21 papers 0 to 25 followers
https://www.readbyqxmd.com/read/29484823/pain-management-using-photobiomodulation-mechanisms-location-and-repeatability-quantified-by-pain-threshold-and-neural-biomarkers-in-mice
#1
Marcelo Victor Pires de Sousa, Masayoshi Kawakubo, Cleber Ferraresi, Beatriz Kaippert, Elisabeth Mateus Yoshimura, Michael R Hamblin
Photobiomodulation (PBM) is a simple, efficient and cost-effective treatment for both acute and chronic pain. We previously showed that PBM applied to the mouse head inhibited nociception in the foot. Nevertheless, the optimum parameters, location for irradiation, duration of the effect, and the mechanisms of action remain unclear. In the present study, the pain threshold in the right hind-paw of mice was studied, after PBM (810 nm CW laser, spot size 1 cm2 or 6 cm2 , 1.2-36 J/cm2 ) applied to various anatomical locations...
February 26, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29126668/comparison-of-the-in-vitro-effects-of-low-level-laser-therapy-and-low-intensity-pulsed-ultrasound-therapy-on-bony-cells-and-stem-cells
#2
REVIEW
Mohammad Bayat, Amarjit Virdi, Fatemehalsadat Rezaei, Sufan Chien
To compare the in vitro effectiveness of Low-Level Laser Therapy (LLLT) and Low Intensity Pulsed Ultrasound (LIPUS) on bony cells and related stem cells. In this study, we aim to systematically review the published scientific literature which explores the use of LLLT and LIPUS to biostimulate the activity or the proliferation of bony cells or stem cells in vitro. We searched the database PubMed for LLLT or LIPUS, with/without bone, osteoblast, osteocyte, stem cells, the human osteosarcoma cell line (MG63), bone-forming cells, and cell culture (or in vitro)...
March 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/29227728/use-of-low-level-laser-therapy-in-treatment-of-the-androgenic-alopecia-the-first-systematic-review
#3
Ibrahim Najem, Hongxiang Chen
Alopecia is a common disease affecting more than half of the world total number of people. Alopecia exists in different types, but one of the most common of these types is the Androgenic Alopecia which has affected approximately 51% of the total number of males ranging between the age bracket of 40 years and 75 years. This type of alopecia is more common in females who are above the age of 65 years and above. Despite this widespread effect, much has not been done regarding identifying the possible drugs for treating this disease...
December 11, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29247431/infrared-photobiomodulation-pbm-therapy-improves-glucose-metabolism-and-intracellular-insulin-pathway-in-adipose-tissue-of-high-fat-fed-mice
#4
Gabriela Silva, Cleber Ferraresi, Rodrigo Teixeira de Almeida, Mariana Lopes Motta, Thiago Paixão, Vinicius Oliveira Ottone, Ivana Alice Fonseca, Murilo Xavier Oliveira, Etel Rocha-Vieira, Marco Fabrício Dias-Peixoto, Elizabethe Adriana Esteves, Cândido Celso Coimbra, Fabiano Trigueiro Amorim, Flávio de Castro Magalhães
Obesity represents a continuously growing global epidemic and is associated with the development of type 2 diabetes mellitus. The etiology of type 2 diabetes is related to the resistance of insulin-sensitive tissues to its action leading to impaired blood glucose regulation. Photobiomodulation (PBM) therapy might be a non-pharmacological, non-invasive strategy to improve insulin resistance. It has been reported that PBM therapy in combination with physical exercise reduces insulin resistance. Therefore, the aim of this study was to investigate the effects of PBM therapy on insulin resistance in obese mice...
April 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/28980210/photobiomodulation-therapy-improves-acute-inflammatory-response-in-mice-the-role-of-cannabinoid-receptors-atp-sensitive-k-channel-p38-mapk-signalling-pathway
#5
Laís M S Neves, Elaine C D Gonçalves, Juliana Cavalli, Graziela Vieira, Larissa R Laurindo, Róli R Simões, Igor S Coelho, Adair R S Santos, Alexandre M Marcolino, Maíra Cola, Rafael C Dutra
Although photobiomodulation therapy (PBM) has been applied clinically for the treatment of pain and inflammation, wound healing, sports and soft tissue injuries, as well as to repair injured spinal cords and peripheral nerves, it remains unclear which molecular substrates (receptor) are implicated in the cellular mechanisms of PBM. Here, we reported that PBM (660 nm, 30 mW, 0.06 cm2, 50 J/cm2, plantar irradiation) significantly inhibited carrageenan-induced paw oedema, but not noxious thermal response, through positive modulation to both CB1 and CB2 cannabinoid receptors...
October 4, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/29091156/low-level-laser-irradiation-promotes-proliferation-of-cryopreserved-adipose-derived-stem-cells
#6
Fernanda Ginani, Diego Moura Soares, Hugo Alexandre de Oliveira Rocha, Carlos Augusto Galvão Barboza
OBJECTIVE: To evaluate the effect of low-level laser irradiation on proliferation and viability of murine adipose-derived stem cells previously submitted to cryopreservation. METHODS: Adipose-derived stem cells were isolated from inguinal fat pads of three mice, submitted to cryopreservation in fetal bovine serum with 10% dimethylsulfoxide for 30 days and then thawed and maintained in normal culture conditions. Culture cells were either irradiated or not (control) with an InGaAIP diode laser at zero and 48 hours, using two different energy densities (0...
July 2017: Einstein
https://www.readbyqxmd.com/read/29099680/pre-exercise-infrared-photobiomodulation-therapy-810%C3%A2-nm-in-skeletal-muscle-performance-and-postexercise-recovery-in-humans-what-is-the-optimal-power-output
#7
Adriano Rodrigues de Oliveira, Adriane Aver Vanin, Shaiane Silva Tomazoni, Eduardo Foschini Miranda, Gianna Móes Albuquerque-Pontes, Thiago De Marchi, Vanessa Dos Santos Grandinetti, Paulo Roberto Vicente de Paiva, Treice Beatriz Gonçalves Imperatori, Paulo de Tarso Camillo de Carvalho, Jan Magnus Bjordal, Ernesto Cesar Pinto Leal-Junior
BACKGROUND: Photobiomodulation therapy (PBMT) has recently been used to alleviate postexercise muscle fatigue and enhance recovery, demonstrating positive results. A previous study by our research group demonstrated the optimal dose for an infrared wavelength (810 nm), but the outcomes could be optimized further with the determination of the optimal output power. OBJECTIVE: The aim of the present study was to evaluate the effects of PBMT (through low-level laser therapy) on postexercise skeletal muscle recovery and identify the best output power...
November 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28593105/photobiomodulation-with-near-infrared-light-helmet-in-a-pilot-placebo-controlled-clinical-trial-in-dementia-patients-testing-memory-and-cognition
#8
Marvin H Berman, James P Halper, Trent W Nichols, H Jarrett, Alan Lundy, Jason H Huang
Alzheimer's disease (AD) is a common, chronic expensive debilitating neurodegenerative disease with no current treatments to prevent the physical deterioration of the brain and the consequent cognitive deficits. The current pathophysiology of Alzheimer's disease is the accumulation of neurofibrillary tangles (NFTs) of hyperphosphorylated tau protein and amyloid-beta (Aβ) plaques. Antibody therapy of Tau and Amyloid beta, vaccines and other methods to decrease Tau and or Amyloid have not been successful after considerable pharmaceutical and biotech efforts...
2017: Journal of neurology and neuroscience
https://www.readbyqxmd.com/read/28646819/invisalign-with-photobiomodulation-optimizing-tooth-movement-and-treatment-efficacy-with-a-novel-self-assessment-algorithm
#9
Todd E Dickerson
No abstract text is available yet for this article.
March 2017: Journal of Clinical Orthodontics: JCO
https://www.readbyqxmd.com/read/28702985/photobiomodulation-with-polarized-light-in-the-treatment-of-cutaneous-and-mucosal-ulcerative-lesions
#10
S E Aragona, F R Grassi, G Nardi, J Lotti, G Mereghetti, E Canavesi, E Equizi, A M Puccio, T Lotti
In recent decades, regenerative medicine has achieved an important evolution at both a conceptual level and scientific production, which explains the current and future possibilities of therapy and daily clinical practice. The main aim of regenerative medicine is the complex system of repair/regeneration. The current literature on the subject demonstrates the advantage of visible light therapy for skin injuries and diseases with the photobiomodulation in which light at low energy levels modulates intra- and extra-cellular photoreceptors by molecular and cellular processes that can stimulate both anti-inflammatory mechanisms and cell proliferative response...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28742438/effect-of-low-level-laser-therapy-on-bone-regeneration-during-osseointegration-and-bone-graft
#11
Randa Zein, Wayne Selting, Stefano Benedicenti
BACKGROUND: The effect of low-level laser therapy (LLLT) on bone regeneration during osseointegration and bone graft is very controversial. Despite many positive reports of in vitro and in vivo studies and more than 50 randomized clinical trials claiming a positive effect of photobiomodulation (PBM), many reports found no significant effect of lasers. OBJECTIVE: The aim of this study was to evaluate studies correlating PBM and bone regeneration and to assesses parameters that produce positive results based on dose and output power used...
December 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29022754/different-protocols-of-photobiomodulation-therapy-of-hyposalivation
#12
Božana Lončar Brzak, Livia Cigić, Marinka Baričević, Ivan Sabol, Marinka Mravak-Stipetić, Dubravko Risović
OBJECTIVE: Photobiomodulation (PBM) therapy has proved to be effective for a wide range of oral pathologies including oral dryness, but the literature still lacks reports of clinical trials and protocols. The purpose of our study was to evaluate the effects of different wavelengths of PBM on salivation in patients suffering from hyposalivation aiming at determination of optimal treatment protocol. MATERIALS AND METHODS: This study included 30 patients whose major salivary glands were treated with low-intensity diode laser BTL2000 (Medical Technologies, s...
February 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29056360/photobiomodulation-therapy-promotes-neurogenesis-by-improving-post-stroke-local-microenvironment-and-stimulating-neuroprogenitor-cells
#13
Luodan Yang, Donovan Tucker, Yan Dong, Chongyun Wu, Yujiao Lu, Yong Li, Juan Zhang, Timon Cheng-Yi Liu, Quanguang Zhang
Recent work has indicated that photobiomodulation (PBM) may beneficially alter the pathological status of several neurological disorders, although the mechanism currently remains unclear. The current study was designed to investigate the beneficial effect of PBM on behavioral deficits and neurogenesis in a photothrombotic (PT) model of ischemic stroke in rats. From day 1 to day 7 after the establishment of PT model, 2-minute daily PBM (CW, 808nm, 350mW/cm2 , total 294J at scalp level) was applied on the infarct injury area (1...
January 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29067616/a-clinical-review-of-phototherapy-for-psoriasis
#14
REVIEW
Ping Zhang, Mei X Wu
Psoriasis is an autoimmune inflammatory skin disease. In the past several decades, phototherapy has been widely used to treat stable psoriatic lesions, including trunk, scalp, arms and legs, and partial nail psoriasis. A variety of light/lasers with different mechanisms of action have been developed for psoriasis including ultraviolet B (UVB), psoralen ultraviolet A (PUVA), pulsed dye laser (PDL), photodynamic therapy (PDT), intense pulsed light (IPL), light-emitting diodes (LED), and so on. Because light/laser each has specific therapeutic and adverse effects, it is important to adequately choose the sources and parameters in management of psoriasis with different pathogenic sites, severities, and duration of the disorder...
January 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/28944964/wnt-%C3%AE-catenin-and-erk-pathway-activation-a-possible-mechanism-of-photobiomodulation-therapy-with-light-emitting-diodes-that-regulate-the-proliferation-of-human-outer-root-sheath-cells
#15
Jung E Kim, Young J Woo, Ki M Sohn, Kwan H Jeong, Hoon Kang
BACKGROUND: Outer root sheath cells (ORSCs) play important roles in maintaining hair follicle structure and provide support for the bulge area. The hair growth promoting effects of photobiomodulation therapy (PBMT) have been reported, but the mechanisms for this in human ORCs (hORSCs) have rarely been studied. OBJECTIVE: The aim of this study was to investigate the effect of various wavelengths of light-emitting diode (LED) irradiation on human ORSCs (hORSCs). METHODS: LED irradiation effects on hORSC proliferation and migration were examined with MTT assay, BrdU incorporation assay and migration assays...
December 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/26714976/treatment-outcomes-of-micropulse-transscleral-cyclophotocoagulation-in-advanced-glaucoma
#16
Sarah Kuchar, Marlene R Moster, Courtney B Reamer, Michael Waisbourd
Glaucoma is the leading cause of irreversible blindness worldwide. The goal of this study was to describe our experience with the novel micropulse transscleral cyclophotocoagulation (MP-TSCPC; IRIDEX IQ810 Laser Systems, CA) in patients with advanced glaucoma. Patients with advanced glaucoma who underwent MP-TSCPC were included in our study. Laser settings were 2000 mW of 810 nm infrared diode laser set on micropulse delivery mode. The laser was delivered over 360° for 100-240 s. The duty cycle was 31.3 %, which translated to 0...
February 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/26949625/photobiomodulation-for-the-treatment-of-retinal-diseases-a-review
#17
REVIEW
Ivayla I Geneva
Photobiomodulation (PBM), also known as low level laser therapy, has recently risen to the attention of the ophthalmology community as a promising new approach to treat a variety of retinal conditions including age-related macular degeneration, retinopathy of prematurity, diabetic retinopathy, Leber's hereditary optic neuropathy, amblyopia, methanol-induced retinal damage, and possibly others. This review evaluates the existing research pertaining to PBM applications in the retina, with a focus on the mechanisms of action and clinical outcomes...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/26673826/effects-of-photobiomodulation-therapy-on-patients-with-primary-open-angle-glaucoma-a-pilot-study
#18
Boris T Ivandic, Tomislav Ivandic
OBJECTIVE: The purpose of this work was to study the safety of photobiomodulation therapy in patients with primary open angle glaucoma (POAG). BACKGROUND DATA: Therapeutic options for POAG focus on lowering the intraocular pressure (IOP) but cannot stop disease progression to irreversible damages. METHODS: The study was designed as a controlled, single-blinded, interventional case series (38 patients; 63 eyes). Low-level laser therapy was performed once or twice per week using a continuous wave (CW) diode laser (780 nm; 10 mW; 292 Hz modulation; 3 mm(2) beam spot)...
December 16, 2015: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/26762247/intraoral-photobiomodulation-induced-orthodontic-tooth-alignment-a-preliminary-study
#19
Timothy Shaughnessy, Alpdogan Kantarci, Chung How Kau, Darya Skrenes, Sanjar Skrenes, Dennis Ma
BACKGROUND: Numerous strategies have been proposed to decrease orthodontic treatment time. Photobiomodulation (PBM) has previously been demonstrated to assist in this objective. The aim of this study was to test if intraoral PBM increases the rate of tooth alignment and reduces the time required to resolve anterior dental crowding. METHODS: Nineteen orthodontic subjects with Class I or Class II malocclusion and Little's Irregularity Index (LII) ≥ 3 mm were selected from a pool of applicants, providing 28 total arches...
January 13, 2016: BMC Oral Health
https://www.readbyqxmd.com/read/26140461/photobiomodulation-with-low-level-diode-laser-promotes-osteoblast-migration-in-an-in-vitro-micro-wound-model
#20
Matilde Tschon, Serena Incerti-Parenti, Simona Cepollaro, Luigi Checchi, Milena Fini
Laser photobiomodulation can improve bone healing, but well-defined treatment parameters are lacking. Saos-2 human osteoblast-like cells were subjected to an in vitro scratch-wound healing assay and irradiated by a 915-nm gallium-aluminum-arsenide diode laser for 0, 48, 96, and 144 s using doses of, respectively, 0, 5, 10, and 15 J/cm(2) . Wound area was measured after 4, 24, 48, and 72 h. Cell viability, DNA content, gene expression, and release of bone-related proteins were evaluated after 24, 48, and 72 h...
July 2015: Journal of Biomedical Optics
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