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General pediatrics

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26 papers 100 to 500 followers
Daniel Demesh, Jordan M Virbalas, John P Bent
IMPORTANCE: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) in children describes neuropsychiatric symptom exacerbations that relate temporally to streptococcal infections. Recent case reports suggest tonsillectomy may effectively reduce these symptoms; however, no consensus treatment guidelines exist. This study examines whether tonsillectomy improves neuropsychiatric symptoms in children with PANDAS who have incomplete response to antibiotic therapy...
March 2015: JAMA Otolaryngology—Head & Neck Surgery
J R Ingram, P N Woo, S L Chua, A D Ormerod, N Desai, A C Kai, K Hood, T Burton, F Kerdel, S E Garner, V Piguet
More than 50 interventions have been used to treat hidradenitis suppurativa (HS), and so therapy decisions can be challenging. Our objective was to summarize and appraise randomized controlled trial (RCT) evidence for HS interventions in adults. Searches were conducted in Medline, Embase, CENTRAL, LILACS, five trials registers and abstracts from eight dermatology conferences until 13 August 2015. Two review authors independently assessed study eligibility, extracted data and assessed methodological quality...
May 2016: British Journal of Dermatology
Pradip P Chaudhari, Michael C Monuteaux, Richard G Bachur
BACKGROUND: Varying urine white blood cell (WBC) thresholds have been recommended for the presumptive diagnosis of urinary tract infection (UTI) among young infants. These thresholds have not been studied with newer automated urinalysis systems that analyze uncentrifuged urine that might be influenced by urine concentration. Our objective was to determine the optimal urine WBC threshold for UTI in young infants by using an automated urinalysis system, stratified by urine concentration...
November 2016: Pediatrics
Alexandra Hudson, Carrie-Lee Trider, Kim Blake
No abstract text is available yet for this article.
January 2017: Pediatrics in Review
Rachel T Clarke, Ann Van den Bruel, Clare Bankhead, Christopher D Mitchell, Bob Phillips, Matthew J Thompson
OBJECTIVE: Leukaemia is the most common cancer of childhood, accounting for a third of cases. In order to assist clinicians in its early detection, we systematically reviewed all existing data on its clinical presentation and estimated the frequency of signs and symptoms presenting at or prior to diagnosis. DESIGN: We searched MEDLINE and EMBASE for all studies describing presenting features of leukaemia in children (0-18 years) without date or language restriction, and, when appropriate, meta-analysed data from the included studies...
October 2016: Archives of Disease in Childhood
Mélanie Labrosse, Arielle Levy, Julie Autmizguine, Jocelyn Gravel
BACKGROUND AND OBJECTIVES: A new noninvasive bladder stimulation technique has been described to obtain clean-catch urine (CCU) in infants aged <30 days. Objectives were (1) to determine proportion and predictive factors for successful CCU collections using a stimulation maneuver technique among infants <6 months and (2) to determine the proportion of bacterial contamination with this method. METHODS: A prospective cohort study was conducted in a tertiary pediatric emergency department among infants <6 months needing a urine sample...
September 2016: Pediatrics
K Krause, C E Grattan, C Bindslev-Jensen, M Gattorno, T Kallinich, H D de Koning, H J Lachmann, D Lipsker, A A Navarini, A Simon, C Traidl-Hoffmann, M Maurer
Urticarial skin reactions are one of the most frequent problems seen by allergists and clinical immunologists in daily practice. The most common reason for recurrent wheals is spontaneous urticaria. There are, however, several less common diseases that present with urticarial rash, such as urticarial vasculitis and autoinflammatory disorders. The latter include cryopyrin-associated periodic syndrome and Schnitzler's syndrome, both rare and disabling conditions mediated by increased interleukin-1 secretion. Apart from the urticarial rash, patients are suffering from a variety of systemic symptoms including recurrent fever attacks, arthralgia or arthritis and fatigue...
December 2012: Allergy
Deborah Fein
No abstract text is available yet for this article.
September 2016: Journal of Developmental and Behavioral Pediatrics: JDBP
Goutham Rao
National guidelines for the diagnosis and management of hypertension in children have been available for nearly 40 years. Unfortunately, knowledge and recognition of the problem by clinicians remain poor. Prevalence estimates are highly variable because of differing standards, populations, and blood pressure (BP) measurement techniques. Estimates in the United States range from 0.3% to 4.5%. Risk factors for primary hypertension include overweight and obesity, male sex, older age, high sodium intake, and African American or Latino ancestry...
August 2016: Pediatrics
Kevin D Pereira, Cindy K Jon, Peter Szmuk, Rande H Lazar, Ron B Mitchell
The management of sleep disordered breathing (SDB) in children differs between institutions, and there is a need for an updated review of current practice. Literature was reviewed using the PubMed database from 1995 to 2015 by four tertiary care providers experienced in the management of children with SDB. Articles were selected for clinical applicability, strength of evidence, and practicality for practicing clinicians. Fifty-five articles were identified by tertiary care providers in pediatric anesthesiology, pediatric pulmonology, sleep medicine, and pediatric otolaryngology...
July 2016: Ear, Nose, & Throat Journal
Doug King, Matt Brughelli, Patria Hume, Conor Gissane
BACKGROUND: Sport-related concussions are a subset of mild traumatic brain injuries and are a concern for many sporting activities worldwide. OBJECTIVE: To review and update the literature in regard to the history, pathophysiology, recognition, assessment, management and knowledge of concussion. METHODS: Searches of electronic literature databases were performed to identify studies published up until April 2013. RESULTS: 292 publications focussing on concussion met the inclusion criteria, and so they were quality rated and reviewed...
April 2014: Sports Medicine
Kevin M Guskiewicz, Johna Register-Mihalik, Paul McCrory, Michael McCrea, Karen Johnston, Michael Makdissi, Jirí Dvorák, Gavin Davis, Willem Meeuwisse
The Sport Concussion Assessment Tool 2 (SCAT2), which evolved from the 2008 Concussion in Sport Group (CISG) Consensus meeting, has been widely used internationally for the past 4 years. Although the instrument is considered very practical and moderately effective for use by clinicians who manage concussion, the utility and sensitivity of a 100-point scoring system for the SCAT2 has been questioned. The 2012 CISG Consensus Meeting provided an opportunity for several of the world's leading concussion researchers and clinicians to present data and to share experiences using the SCAT2...
April 2013: British Journal of Sports Medicine
Megan A Moreno
No abstract text is available yet for this article.
June 1, 2016: JAMA Pediatrics
Jane M Lavelle, Mercedes M Blackstone, Mary Kate Funari, Christine Roper, Patricia Lopez, Aileen Schast, April M Taylor, Catherine B Voorhis, Mira Henien, Kathy N Shaw
BACKGROUND AND OBJECTIVES: Urinary tract infection (UTI) screening in febrile young children can be painful and time consuming. We implemented a screening protocol for UTI in a high-volume pediatric emergency department (ED) to reduce urethral catheterization, limiting catheterization to children with positive screens from urine bag specimens. METHODS: This quality-improvement initiative was implemented using 3 Plan-Do-Study-Act cycles, beginning with a small test of the proposed change in 1 ED area...
July 2016: Pediatrics
Sharon Levy, Fatma Dedeoglu, Jonathan M Gaffin, Katharine C Garvey, Elizabeth Harstad, Andrew MacGinnitie, Paul A Rufo, Qian Huang, Rosemary E Ziemnik, Lauren E Wisk, Elissa R Weitzman
BACKGROUND: In an effort to reduce barriers to screening for alcohol use in pediatric primary care, the National Institute on Alcoholism and Alcohol Abuse (NIAAA) developed a two-question Youth Alcohol Screening Tool derived from population-based survey data. It is unknown whether this screening tool, designed for use with general populations, accurately identifies risk among youth with chronic medical conditions (YCMC). This growing population, which comprises nearly one in four youth in the US, faces a unique constellation of drinking-related risks...
2016: PloS One
Paul L Aronson, Cary Thurm, Derek J Williams, Lise E Nigrovic, Elizabeth R Alpern, Joel S Tieder, Samir S Shah, Russell J McCulloh, Fran Balamuth, Amanda C Schondelmeyer, Evaline A Alessandrini, Whitney L Browning, Angela L Myers, Mark I Neuman
BACKGROUND: Differences among febrile infant institutional clinical practice guidelines (CPGs) may contribute to practice variation and increased healthcare costs. OBJECTIVE: Determine the association between pediatric emergency department (ED) CPGs and laboratory testing, hospitalization, ceftriaxone use, and costs in febrile infants. DESIGN: Retrospective cross-sectional study in 2013. SETTING: Thirty-three hospitals in the Pediatric Health Information System...
June 2015: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Borja Gomez, Santiago Mintegi, Javier Benito
BACKGROUND: Little is known about the value of leukopenia for assessing the risk of having a bacterial infection in young febrile infants. METHODS: Infants younger than 90 days with fever without source were prospectively recruited between October 2011 and September 2013 in 19 Spanish Pediatric Emergency Departments. We analyzed the prevalence of invasive bacterial infection (IBI, positive blood or cerebrospinal fluid culture) and non-IBI (urinary tract infections and any other microbiologically confirmed bacterial infection excluding IBIs) by leukocyte count and general appearance...
January 2016: Pediatric Infectious Disease Journal
Kao-Ping Chua, Mark I Neuman, J Michael McWilliams, Paul L Aronson
OBJECTIVE: To describe the association between clinical outcomes and clinical practice guidelines (CPGs) recommending universal cerebrospinal fluid (CSF) testing in the emergency department for febrile infants aged 29-56 days. STUDY DESIGN: Using 2007-2013 administrative data from 32 US children's hospitals, we performed a difference-in-differences analysis comparing 7 hospitals with CPGs recommending universal CSF testing for older febrile infants aged 29-56 days (CPG group) with 25 hospitals without such CPGs (control group)...
December 2015: Journal of Pediatrics
Natalie M Colaneri, Sarah A Keim, Andrew Adesman
OBJECTIVE: The recent rise in ADHD has prompted concerns about adolescents with ADHD diverting and/or misusing stimulants. This is the first study to assess physician perceptions of the pervasiveness of these issues. METHOD: Questionnaires were mailed to a national sample of pediatric subspecialists. Responses were analyzed (n = 826; 18% response rate) using descriptive statistics and regression analyses. RESULTS: In the past year, 59% of physicians suspected ≥1 patient(s) with ADHD diverted stimulants...
May 19, 2016: Journal of Attention Disorders
Jaume Campistol, María Díez-Juan, Laura Callejón, Aroa Fernandez-De Miguel, Mercedes Casado, Angels Garcia Cazorla, Reymundo Lozano, Rafael Artuch
AIM: To perform metabolic testing on 406 patients (age range 3-22y [mean 6.71, SD 4.15], 343 males and 63 females) with nonsyndromic autism spectrum disorders (ASD) to assess the diagnostic yield. In addition, we reviewed our hospital's clinical database of 8500 patients who had undergone metabolic testing to be identified for inborn errors of metabolism (IEM), and described the characteristics of those with IEM and nonsyndromic ASD. METHOD: Neuropsychological evaluation included the Social Communication Questionnaire and Child Behavior Checklist...
August 2016: Developmental Medicine and Child Neurology
2016-05-21 17:52:28
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