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Daniela Poli, Emilia Antonucci, Francesco Dentali, Nicoletta Erba, Sophie Testa, Eros Tiraferri, Gualtiero Palareti
OBJECTIVE: To evaluate the risk of recurrent intracranial hemorrhage (ICH) in patients on vitamin K antagonists (VKAs) after a first episode of ICH. METHODS: The Cerebral Haemorrhage in patients Restarting Oral Anticoagulant Therapy (CHIRONE) Study collected data of patients eligible for the study from the database of 27 centers affiliated with the Italian Federation of Anticoagulation Clinics. RESULTS: We enrolled 267 patients (163 male, median age 73...
March 25, 2014: Neurology
Lori-Ann Linkins
Vitamin K antagonists are widely used for the prevention of stroke due to atrial fibrillation, treatment and secondary prevention of venous thromboembolism, prevention of valvular thromboembolism in patients with prosthetic heart valves, and secondary prevention of acute myocardial infarction. The most common adverse event experienced by patients receiving anticoagulant therapy is major bleeding. The incidence of major bleeding in patients receiving long-term anticoagulation with a vitamin K antagonist in contemporary studies is 1-3% per year...
May 2013: Blood Reviews
John G Kelton, Donald M Arnold, Shannon M Bates
No abstract text is available yet for this article.
February 21, 2013: New England Journal of Medicine
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