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Christophe Baudouin, Elisabeth M Messmer, Pasquale Aragona, Gerd Geerling, Yonca A Akova, José Benítez-del-Castillo, Kostas G Boboridis, Jesús Merayo-Lloves, Maurizio Rolando, Marc Labetoulle
Meibomian gland dysfunction (MGD) is the most frequent cause of dry eye disease (DED). Eyelid inflammation, microbial growth, associated skin disorders as well as potentially severe corneal complications culminate to make MGD a complex multifactorial disorder. It is probable that MGD is a heterogeneous condition arising from any combination of the following five separate pathophysiological mechanisms: eyelid inflammation, conjunctival inflammation, corneal damage, microbiological changes and DED resulting from tear film instability...
March 2016: British Journal of Ophthalmology
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