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General Medicine

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Jason R Miller, Karl W Dunn, Domenick Braccia, Louis J Ciliberti, Dina K Becker, Joshua K Hollinger, Shelley M Brand
Lyme disease is the result of Borrelia burgdorferi bacterial infection after exposure from a tick bite. A pathognomonic finding in early-stage Lyme disease is an expanding, red macular ring known as erythema migrans. Lyme arthritis is a late-stage manifestation of this disease, affecting the large, weightbearing joints with intermittent pain and swelling. The existing data on Lyme disease and subsequent arthritis have reported manifestations in the lower extremity, primarily in the knee and ankle and less commonly the small joints of the foot...
July 16, 2015: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
Andreas Greinacher
New England Journal of Medicine, Volume 373, Issue 3, Page 252-261, July 2015.
July 16, 2015: New England Journal of Medicine
F G R Fowkes, G D Murray, I Butcher, C L Heald, R J Lee, L E Chambless, A R Folsom, A T Hirsch, M Dramaix, G deBacker, J-C Wautrecht, M Kornitzer, A B Newman, M Cushman, K Sutton-Tyrrell, F G R Fowkes, A J Lee, J F Price, R B d'Agostino, J M Murabito, P E Norman, K Jamrozik, J D Curb, K H Masaki, B L Rodríguez, J M Dekker, L M Bouter, R J Heine, G Nijpels, C D A Stehouwer, L Ferrucci, M M McDermott, H E Stoffers, J D Hooi, J A Knottnerus, M Ogren, B Hedblad, J C Witteman, M M B Breteler, M G M Hunink, A Hofman, M H Criqui, R D Langer, A Fronek, W R Hiatt, R Hamman, H E Resnick, J Guralnik, M M McDermott
CONTEXT: Prediction models to identify healthy individuals at high risk of cardiovascular disease have limited accuracy. A low ankle brachial index (ABI) is an indicator of atherosclerosis and has the potential to improve prediction. OBJECTIVE: To determine if the ABI provides information on the risk of cardiovascular events and mortality independently of the Framingham risk score (FRS) and can improve risk prediction. DATA SOURCES: Relevant studies were identified...
July 9, 2008: JAMA: the Journal of the American Medical Association
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