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Diabetes Technology

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3 papers 0 to 25 followers
By Ehud Ur Professor and Head, Endocrinology, UBC, Vancouver
https://www.readbyqxmd.com/read/26850709/day-and-night-glycaemic-control-with-a-bionic-pancreas-versus-conventional-insulin-pump-therapy-in-preadolescent-children-with-type-1-diabetes-a-randomised-crossover-trial
#1
Steven J Russell, Mallory A Hillard, Courtney Balliro, Kendra L Magyar, Rajendranath Selagamsetty, Manasi Sinha, Kerry Grennan, Debbie Mondesir, Laya Ehklaspour, Hui Zheng, Edward R Damiano, Firas H El-Khatib
BACKGROUND: The safety and efficacy of continuous, multiday, automated glycaemic management has not been tested in outpatient studies of preadolescent children with type 1 diabetes. We aimed to compare the safety and efficacy of a bihormonal bionic pancreas versus conventional insulin pump therapy in this population of patients in an outpatient setting. METHODS: In this randomised, open-label, crossover study, we enrolled preadolescent children (aged 6-11 years) with type 1 diabetes (diagnosed for ≥1 year) who were on insulin pump therapy, from two diabetes camps in the USA...
March 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/24931572/outpatient-glycemic-control-with-a-bionic-pancreas-in-type-1-diabetes
#2
RANDOMIZED CONTROLLED TRIAL
Steven J Russell, Firas H El-Khatib, Manasi Sinha, Kendra L Magyar, Katherine McKeon, Laura G Goergen, Courtney Balliro, Mallory A Hillard, David M Nathan, Edward R Damiano
BACKGROUND: The safety and effectiveness of automated glycemic management have not been tested in multiday studies under unrestricted outpatient conditions. METHODS: In two random-order, crossover studies with similar but distinct designs, we compared glycemic control with a wearable, bihormonal, automated, "bionic" pancreas (bionic-pancreas period) with glycemic control with an insulin pump (control period) for 5 days in 20 adults and 32 adolescents with type 1 diabetes mellitus...
July 24, 2014: New England Journal of Medicine
https://www.readbyqxmd.com/read/26742082/an-overview-of-insulin-pumps-and-glucose-sensors-for-the-generalist
#3
REVIEW
Brooke H McAdams, Ali A Rizvi
Continuous subcutaneous insulin, or the insulin pump, has gained popularity and sophistication as a near-physiologic programmable method of insulin delivery that is flexible and lifestyle-friendly. The introduction of continuous monitoring with glucose sensors provides unprecedented access to, and prediction of, a patient's blood glucose levels. Efforts are underway to integrate the two technologies, from "sensor-augmented" and "sensor-driven" pumps to a fully-automated and independent sensing-and-delivery system...
2016: Journal of Clinical Medicine
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