Lauren M Postlewait, Malcolm H Squires, David A Kooby, George A Poultsides, Sharon M Weber, Mark Bloomston, Ryan C Fields, Timothy M Pawlik, Konstantinos I Votanopoulos, Carl R Schmidt, Aslam Ejaz, Alexandra W Acher, David J Worhunsky, Neil Saunders, Douglas Swords, Linda X Jin, Clifford S Cho, Emily R Winslow, Kenneth Cardona, Charles A Staley, Shishir K Maithel
BACKGROUND: Conflicting data exist on the prognostic implication of signet-ring cell (SRC) histology in gastric adenocarcinoma (GAC). METHODS: All patients who underwent curative-intent resection of GAC from the seven institutions of the U.S. Gastric Cancer Collaborative between 2000 and 2012 were included. Primary end points were recurrence-free survival (RFS) and overall survival (OS). Stage-specific analyses were performed. RESULTS: A total of 768 patients met the inclusion criteria...
December 2015: Annals of Surgical Oncology