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Idiopathic Intracranial Hypertension literature

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14 papers 25 to 100 followers
https://www.readbyqxmd.com/read/26888960/evolving-evidence-in-adult-idiopathic-intracranial-hypertension-pathophysiology-and-management
#1
REVIEW
Susan P Mollan, Fizzah Ali, Ghaniah Hassan-Smith, Hannah Botfield, Deborah I Friedman, Alexandra J Sinclair
Idiopathic intracranial hypertension (IIH) is a rare but important disease associated with significant morbidity. There is an expected rise in prevalence in line with the escalating global burden of obesity. Modern revisions in the terminology and diagnostic criteria for IIH help guide clinicians in investigations and researchers in standardising recruitment criteria for clinical trials. The pathophysiology of IIH is incompletely characterised; suggested underpinning mechanisms include the role of cerebrospinal fluid regulation as well as metabolic and endocrinological perspectives...
September 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/26713173/over-drainage-and-persistent-shunt-dependency-in-patients-with-idiopathic-intracranial-hypertension-treated-with-shunts-and-bariatric-surgery
#2
Jonathan Roth, Shlomi Constantini, Anat Kesler
BACKGROUND: Idiopathic intracranial hypertension (IIH) may lead to visual impairment. Shunt surgery is indicated for refractory IIH-related symptoms that persist despite medical treatment, or those presenting with significant visual decline. Obesity is a risk factor for IIH; a reduction in weight has been shown to improve papilledema. Bariatric surgery (BS) has been suggested for treating IIH associated with morbid obesity. In this study, we describe a high rate of over-drainage (OD) seen in patients following shunts and BS...
2015: Surgical Neurology International
https://www.readbyqxmd.com/read/26747875/prevalence-of-dural-venous-sinus-stenosis-and-hypoplasia-in-a-generalized-population
#3
Christopher R Durst, David A Ornan, Michael A Reardon, Prachi Mehndiratta, Sugoto Mukherjee, Robert M Starke, Max Wintermark, Avery Evans, Mary E Jensen, R Webster Crowley, John Gaughen, Kenneth C Liu
BACKGROUND AND PURPOSE: While recent literature has described the prevalence of transverse sinus stenosis in patients with idiopathic intracranial hypertension, tinnitus, and refractory headaches, it is unclear what the prevalence is in the general population. This study evaluates the prevalence of venous sinus stenosis and hypoplasia in the general patient population. MATERIALS AND METHODS: 355 of 600 consecutive patients who underwent CT angiography of the head met the inclusion criteria...
November 2016: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/26302017/are-shunt-series-and-shunt-patency-studies-useful-in-patients-with-shunted-idiopathic-intracranial-hypertension-in-the-emergency-department
#4
Ann Liu, Benjamin D Elder, Eric W Sankey, C Rory Goodwin, Ignacio Jusué-Torres, Daniele Rigamonti
OBJECTIVES: Shunt series and shunt patency studies can be performed in the emergency department (ED) to evaluate for shunt malfunction in patients with idiopathic intracranial hypertension (IIH). Here, we examine the utility of these studies in this specific patient population. METHODS: We retrospectively reviewed the ED visits of all shunted patients diagnosed with IIH from 2003 to 2014. ED visits for symptoms not related to the patient's IIH were excluded from the study...
November 2015: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/26439045/evaluation-of-aqueductal-csf-flow-dynamics-with-phase-contrast-cine-mr-imaging-in-idiopathic-intracranial-hypertension-patients-preliminary-results
#5
R Akay, O Kamisli, A Kahraman, S Oner, M Tecellioglu
OBJECTIVE: We aimed to evaluate dynamic cerebrospinal fluid (CSF) flow in idiopathic intracranial hypertension (IIH) patients with new MRI technology phase contrast cine (PCC) MRI. PATIENTS AND METHODS: Nineteen patients diagnosed with idiopathic intracranial hypertension and 11 healthy volunteers were included in this study. Nine of the IIH cases had been previously diagnosed and had been on drug treatment and 10 cases were diagnosed with IIH recently and had not been put on drug treatment yet...
September 2015: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/26446855/surgically-managed-idiopathic-intracranial-hypertension-in-adults-a-single-centre-experience
#6
Samir A Matloob, Ahmed K Toma, Lewis Thorne, Laurence D Watkins
INTRODUCTION: Idiopathic intracranial hypertension (IIH) is a rare condition that is often managed conservatively. In patients with aggressive progression of the disease surgical options are considered. There are few data on the outcomes of these patients when surgically managed. We describe our experience of surgically managed IIH and the outcomes of these patients, in particular the surgical revision rate and interventions required for resolution of symptoms. METHODS: A retrospective review of all patient files coded with benign intracranial hypertension, idiopathic intracranial hypertension or pseudotumour cerebri was undertaken...
December 2015: Acta Neurochirurgica
https://www.readbyqxmd.com/read/26457687/brain-imaging-in-idiopathic-intracranial-hypertension
#7
REVIEW
Samuel Bidot, Amit M Saindane, Jason H Peragallo, Beau B Bruce, Nancy J Newman, Valérie Biousse
BACKGROUND: The primary role of brain imaging in idiopathic intracranial hypertension (IIH) is to exclude other pathologies causing intracranial hypertension. However, subtle radiologic findings suggestive of IIH have emerged with modern neuroimaging. This review provides a detailed description of the imaging findings reported in IIH and discusses their possible roles in the pathophysiology and the diagnosis of IIH. EVIDENCE ACQUISITION: References were identified by searches of PubMed from 1955 to January 2015, with the terms "idiopathic intracranial hypertension," "pseudotumor cerebri," "intracranial hypertension," "benign intracranial hypertension," "magnetic resonance imaging," "magnetic resonance venography," "computed tomography (CT)," "CT venography," "imaging," and "cerebrospinal fluid (CSF) leak...
December 2015: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/26516306/current-status-of-the-application-of-intracranial-venous-sinus-stenting
#8
REVIEW
Kan Xu, Tiecheng Yu, Yongjie Yuan, Jinlu Yu
The intracranial venous sinus is an important component of vascular disease. Many diseases involve the venous sinus and are accompanied by venous sinus stenosis (VSS), which leads to increased venous pressure and high intracranial pressure. Recent research has focused on stenting as a treatment for VSS related to these diseases. However, a systematic understanding of venous sinus stenting (VS-Stenting) is lacking. Herein, the literature on idiopathic intracranial hypertension (IIH), venous pulsatile tinnitus, sinus thrombosis, high draining venous pressure in dural arteriovenous fistula (AVF) and arteriovenous malformation (AVM), and tumor-caused VSS was reviewed and analyzed to summarize experiences with VS-Stenting as a treatment...
2015: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/26566039/cerebral-venous-thrombosis-current-and-newer-anticoagulant-treatment-options
#9
REVIEW
Salma I Patel, Hiba Obeid, Lana Matti, Harish Ramakrishna, Fadi E Shamoun
BACKGROUND: Cerebral venous thrombosis (CVT) is rare and involves thrombosis of the veins and sinuses of the brain, most commonly the superior sagittal sinus. Approximately 5 CVT cases occur per 1 million persons in western countries. CVT causes 0.5% of strokes. Early diagnosis is crucial to prevent such outcomes as hydrocephalus, intracranial hypertension, and further seizures. Standard medical treatment of CVT consists of low-molecular-weight heparin and endovascular thrombolysis. Small case reports have found that the newer oral anticoagulants can be used for CVT treatment; however, they are associated with increased risk of bleeding and other adverse effects...
November 2015: Neurologist
https://www.readbyqxmd.com/read/26587297/elevated-intracranial-pressure-diagnosis-with-emergency-department-bedside-ocular-ultrasound
#10
D Amin, T McCormick, T Mailhot
Bedside sonographic measurement of optic nerve sheath diameter can aid in the diagnosis of elevated intracranial pressure in the emergency department. This case report describes a 21-year-old female presenting with 4 months of mild headache and 2 weeks of recurrent, transient binocular vision loss. Though limited by patient discomfort, fundoscopic examination suggested the presence of blurred optic disc margins. Bedside ocular ultrasound (BOUS) revealed wide optic nerve sheath diameters and bulging optic discs bilaterally...
2015: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/26587993/safety-and-tolerability-of-acetazolamide-in-the-idiopathic-intracranial-hypertension-treatment-trial
#11
RANDOMIZED CONTROLLED TRIAL
Martin W ten Hove, Deborah I Friedman, Anil D Patel, Isabella Irrcher, Michael Wall, Michael P McDermott
OBJECTIVE: To examine the tolerability and adverse events reported in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT). METHODS: Randomized, double-masked, placebo-controlled clinical trial. Trial participants (n = 165) with mild visual loss concurrently receiving low-sodium weight-reduction diet plus the maximally tolerated dosage of acetazolamide (up to 4 g/d) or placebo for 6 months. MAIN OUTCOMES MEASURES: adverse events (AEs), assessment of clinical and laboratory findings at study visits...
March 2016: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/26618282/factors-affecting-visual-field-outcomes-in-the-idiopathic-intracranial-hypertension-treatment-trial
#12
RANDOMIZED CONTROLLED TRIAL
Kimberly E Cello, John L Keltner, Chris A Johnson, Michael Wall
BACKGROUND: To determine the prevalence of visual field (VF) performance failures (PF) and treatment failures (TFs), and identify factors associated with PFs in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT). METHODS: A total of 165 participants from 38 sites with idiopathic intracranial hypertension (IIH) and mild visual loss were randomized to either acetazolamide-plus diet or placebo-plus diet. The IIHTT Visual Field Reading Center evaluated 2950 Swedish Interactive Threshold Algorithm Standard 24-2 VFs from the enrolled participants...
March 2016: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/26641809/current-concepts-in-pseudotumor-cerebri
#13
REVIEW
Clotilde Hainline, Janet C Rucker, Laura J Balcer
PURPOSE OF REVIEW: Idiopathic intracranial hypertension (IIH) is a potentially blinding disorder of unknown cause, characterized by elevated intracranial pressure in the absence of a mass lesion, venous sinus thrombosis, or meningitis. This review summarizes recent developments and insights from leading treatment trials, emerging treatment options, and evolving ways to evaluate IIH. RECENT FINDINGS: The Idiopathic Intracranial Hypertension Treatment Trial is the first large-scale, randomized, prospective study to evaluate medical treatment of patients with mild vision loss...
February 2016: Current Opinion in Neurology
https://www.readbyqxmd.com/read/26700907/understanding-idiopathic-intracranial-hypertension-mechanisms-management-and-future-directions
#14
REVIEW
Keira A Markey, Susan P Mollan, Rigmor H Jensen, Alexandra J Sinclair
Idiopathic intracranial hypertension is a disorder characterised by raised intracranial pressure that predominantly affects young, obese women. Pathogenesis has not been fully elucidated, but several causal factors have been proposed. Symptoms can include headaches, visual loss, pulsatile tinnitus, and back and neck pain, but the clinical presentation is highly variable. Although few studies have been done to support evidence-based management, several recent advances have the potential to enhance understanding of the causes of the disease and to guide treatment decisions...
January 2016: Lancet Neurology
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