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Emily C O'Brien, DaJuanicia N Simon, Laine E Thomas, Elaine M Hylek, Bernard J Gersh, Jack E Ansell, Peter R Kowey, Kenneth W Mahaffey, Paul Chang, Gregg C Fonarow, Michael J Pencina, Jonathan P Piccini, Eric D Peterson
BACKGROUND: Therapeutic decisions in atrial fibrillation (AF) are often influenced by assessment of bleeding risk. However, existing bleeding risk scores have limitations. OBJECTIVES: We sought to develop and validate a novel bleeding risk score using routinely available clinical information to predict major bleeding in a large, community-based AF population. METHODS: We analysed data from Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF), a prospective registry that enrolled incident and prevalent AF patients at 176 US sites...
December 7, 2015: European Heart Journal
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