K Krause, C E Grattan, C Bindslev-Jensen, M Gattorno, T Kallinich, H D de Koning, H J Lachmann, D Lipsker, A A Navarini, A Simon, C Traidl-Hoffmann, M Maurer
Urticarial skin reactions are one of the most frequent problems seen by allergists and clinical immunologists in daily practice. The most common reason for recurrent wheals is spontaneous urticaria. There are, however, several less common diseases that present with urticarial rash, such as urticarial vasculitis and autoinflammatory disorders. The latter include cryopyrin-associated periodic syndrome and Schnitzler's syndrome, both rare and disabling conditions mediated by increased interleukin-1 secretion. Apart from the urticarial rash, patients are suffering from a variety of systemic symptoms including recurrent fever attacks, arthralgia or arthritis and fatigue...
December 2012: Allergy