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Back pain

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4 papers 0 to 25 followers
Kang Li, Yan Li, Zhenjiang Ma, Jie Zhao
As intervertebral disc (IVD) degeneration has been proven to contribute to low back pain (LBP), drug treatment aiming at attenuating IVD degeneration may prove to be benefiical. Crocin, a bioactive component of saffron, has been found to exert anti-inflammatory effects on cartilage. In the present study, the anti-inflammatory and anti-catabolic effects of crocin on rat IVDs were analyzed in vitro and ex vivo. Nucleus pulposus (NP) cells were isolated from the lumbar IVDs of Sprague-Dawley rats. The NP cells were first treated with various concentrations of crocin, and then stimulated with lipopolysaccharide (LPS) to induce inflammation...
November 2015: International Journal of Molecular Medicine
Fernanda Queiroz Ribeiro Cerci Mostagi, Josilainne Marcelino Dias, Ligia Maxwell Pereira, Karen Obara, Bruno Fles Mazuquin, Mariana Felipe Silva, Monica Angelica Cardoso Silva, Renata Rosa de Campos, Maria Simone Tavares Barreto, Jéssyca Fernandes Nogueira, Tarcísio Brandão Lima, Rodrigo Luiz Carregaro, Jefferson Rosa Cardoso
Low back pain (LBP) is one of the most common causes of disability, and the Pilates method has been associated with improvements in symptoms. The purpose of this study was to assess the effectiveness of the Pilates method, when compared to general exercises, on pain and functionality after eight weeks (16 sessions, 2×/week) and a follow-up of three months, in subjects with non-specific chronic low back pain (NSCLBP). A randomised controlled trial composed of 22 subjects was proposed. Subjects were allocated into two groups: the Pilates group (PG) (n = 11) and the general exercise group (GEG) (n = 11)...
October 2015: Journal of Bodywork and Movement Therapies
Seyed Masoud Hashemi, Mohamad Reza Aryani, Sirus Momenzadeh, Seyed Sajad Razavi, Gholamreza Mohseni, Seyed Amir Mohajerani, Ali Akbar Esmilijah
BACKGROUND: Epidural steroid injection (ESI), including transforaminal (TF) epidural injections and interlaminar (IL) epidural steroid injections are commonly performed procedures for the management of lumbosacral radicular pain. Parasagittal interlaminar (PIL) approach could enable higher ventral epidural spread, with fewer complications than TF. OBJECTIVES: This study aims to compare the effectiveness of PIL and TF ESI in relieving the pain and disability of patients with lumbosacral pain...
October 2015: Anesthesiology and Pain Medicine
Jo Nijs, Adri Apeldoorn, Hank Hallegraeff, Jacqui Clark, Rob Smeets, Annaleen Malfliet, Enrique L Girbes, Margot De Kooning, Kelly Ickmans
BACKGROUND: Low back pain (LBP) is a heterogeneous disorder including patients with dominant nociceptive (e.g., myofascial low back pain), neuropathic (e.g., lumbar radiculopathy), and central sensitization pain. In order to select an effective and preferably also efficient treatment in daily clinical practice, LBP patients should be classified clinically as either predominantly nociceptive, neuropathic, or central sensitization pain. OBJECTIVE: To explain how clinicians can differentiate between nociceptive, neuropathic, and central sensitization pain in patients with LBP...
May 2015: Pain Physician
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